Comparative Transcriptomics Analysis Reveals Unique Immune Response to Grass Carp Reovirus Infection in Barbel Chub (Squaliobarbus curriculus) [PDF]
BiologyGrass carp (Ctenopharyngodon idella) and barbel chub (Squaliobarbus curriculus)—both Leuciscinae subfamily species—demonstrate differences in grass carp reovirus (GCRV) infection resistance.
Yuhong Huang +7 more
doaj +2 more sources
Prediction of GCRV virus-host protein interactome based on structural motif-domain interactions [PDF]
BMC Bioinformatics, 2017 Grass carp hemorrhagic disease, caused by grass carp reovirus (GCRV), is the most fatal causative agent in grass carp aquaculture. Protein-protein interactions between virus and host are one avenue through which GCRV can trigger infection and induce disease.
Aidi Zhang, Libo He, Yaping Wang
openaire +4 more sources
Characterization of the NFAT Gene Family in Grass Carp (Ctenopharyngodon idellus) and Functional Analysis of NFAT1 During GCRV Infection [PDF]
FishesNuclear factors of activated T cells (NFATs) are pivotal regulatory factors of immune responses, primarily by modulating T cell activity and regulating inflammatory cytokine gene transcription.
Yao Shen +8 more
doaj +2 more sources
Differences in responses of grass carp to different types of grass carp reovirus (GCRV) and the mechanism of hemorrhage revealed by transcriptome sequencing [PDF]
BMC Genomics, 2017 Background Grass carp is an important farmed fish in China that is affected by serious disease, especially hemorrhagic disease caused by grass carp reovirus (GCRV).
Libo He +8 more
doaj +2 more sources
poly(I:C), chitosan oligosaccharide, and chitosan enhance inactivated GCRV vaccine potency in grass carp Ctenopharyngodon idella [PDF]
Comparative Immunology ReportsVaccination is the most promising strategy to combat infectious diseases. Vaccine adjuvants are considered as key components in modern vaccinology since they provide the necessary help in enhancing the immune responses.
Qingqing Tian, Yanqi Zhang, Jianguo Su
doaj +2 more sources
Temperature dependency of GCRV infection. [PDF]
, 2023 (A) Double-axis graph depicting the GCHD survey results from 46 fisheries in Hunan province in the last three years (2019–2021). The historical weather data for daily high (red line) and low (blue line) temperatures and the statistics of GCHD outbreaks ...
Rui Song (331963) +13 more
core +3 more sources
The Role of Gut Microbiota in Fish Viral Infection: Mechanisms and Microbiota-Targeted Interventions. [PDF]
Aquac NutrViral diseases represent one of the major threats to the global aquaculture industry. In recent years, the relationship between gut microbiota and viral infections in fish has garnered increasing attention. The gut microbiota contributes critically to fish health and is involved in antiviral defense through immune regulation, secretion of microbial ...
Zhao Q, Shao J, Chen Y, Zhang H.
europepmc +2 more sources
Viruses, 2021 Grass carp reovirus (GCRV) causes serious losses to the grass carp industry. At present, infectious tissues of GCRV have been studied, but target cells remain unclear. In this study, peripheral blood cells were isolated, cultured, and infected with GCRV.
Ling Yang, Jianguo Su
doaj +1 more source
Grass Carp Reovirus Induces Formation of Lipid Droplets as Sites for Its Replication and Assembly
mBio, 2022 Grass carp is an important commercial fish in China that is plagued by various diseases, especially the hemorrhagic disease induced by grass carp reovirus (GCRV).
Libo He +9 more
doaj +1 more source
IL6-STAT3-HSP90 axis regulates GCRV entry. [PDF]
, 2023 (A) GCO/CIK cells infected with GCRV (MOI = 5) at different temperatures for 1 h were prepared to quantify the relative genome entry by RT-PCR with the VP7 primer pair.
Rui Song (331963) +13 more
core +1 more source