Results 41 to 50 of about 1,339 (193)

Structural and functional analysis of the small GTPase ARF1 reveals a pivotal role of its GTP-binding domain in controlling of the generation of viral inclusion bodies and replication of grass carp reovirus

Frontiers in Immunology, 2022
Grass carp reovirus (GCRV) is the most pathogenic double-stranded (ds) RNA virus among the isolated aquareoviruses. The molecular mechanisms by which GCRV utilizes host factors to generate its infectious compartments beneficial for viral replication and ...
Jie Zhang, Pengwei Li, Pengwei Li, Riye Lu, Songying Ouyang, Ming Xian Chang, Ming Xian Chang, Ming Xian Chang   +7 more
doaj   +1 more source

Fish disease prevention via microbial dysbiosis‐associated biomarkers in aquaculture

Reviews in Aquaculture, Volume 15, Issue 2, Page 579-594, March 2023., 2023
Abstract Infectious diseases are a major burden in aquaculture, and represent a significant yield‐limiting factor in production that is costly to manage as well as a potential vector for zoonoses. Over the past decades, a range of new diseases have emerged, alongside increased levels of antibiotic resistance, thus heightening the need for improved ...
Julia Mougin, Alyssa Joyce
wiley   +1 more source

Characterization, Expression, and Ligand Binding of LGP2 and MDA5 in Largemouth Black Bass Micropterus salmoides (Lacepède, 1802)

Aquaculture Research, Volume 2023, Issue 1, 2023., 2023
Melanoma differentiation‐associated gene 5 (MDA5) and the laboratory of genetics and physiology 2 (LGP2) are family members of retinoic acid‐inducible gene I (RIG‐I)‐like receptors (RLRs), which play important roles in the immune response against pathogens invasion.
Xiangyu Pi, Yang Xu, Yiwen Cao, Qihuan Zhang, Zisheng Wang, Zhitao Qi, Mohamed Abdelsalam   +6 more
wiley   +1 more source

Bid-deficient fish delay grass carp reovirus (GCRV) replication and attenuate GCRV-triggered apoptosis

Oncotarget, 2017
Bid, BH3-interacting domain death agonist, is a pro-apoptotic BH3-only member of Bcl-2 family, playing an important role in apoptosis. In the study, Bid genes from grass carp (Ctenopharyngodon idellus) and rare minnow (Gobiocypris rarus), named CiBid and GrBid, were cloned and analyzed.
He, Libo, Wang, Hao, Luo, Lifei, Li, Yongming, Huang, Rong, Liao, Lanjie, Zhu, Zuoyan, Wang, Yaping   +7 more
openaire   +2 more sources

Bioinformatics of Recent Aqua- and Orthoreovirus Isolates from Fish: Evolutionary Gain or Loss of FAST and Fiber Proteins and Taxonomic Implications [PDF]

, 2013
Family Reoviridae, subfamily Spinareovirinae, includes nine current genera. Two of these genera, Aquareovirus and Orthoreovirus, comprise members that are closely related and consistently share nine homologous proteins.
Duncan, Roy, Nibert, Max L.
core   +3 more sources

Subnanometer-resolution structures of the grass carp reovirus core and virion. [PDF]

, 2008
Grass carp reovirus (GCRV) is a member of the Aquareovirus genus of the family Reoviridae, a large family of double-stranded RNA (dsRNA) viruses infecting plants, insects, fishes and mammals.
Atanasov, Ivo C, Cheng, Lingpeng, Fang, Qin, Shah, Sanket, Zhou, Z Hong   +4 more
core   +1 more source

Whole-genome characterization of human group C rotaviruses: identification of two lineages in the VP3 gene [PDF]

, 2011
Group C rotavirus (GCRV) is distributed worldwide as an enteric pathogen in humans and animals. However, to date, whole-genome sequences are available only for a human strain (Bristol) and a porcine strain (Cowden).
Chawla-Sarkar, Mamta, Ghosh, Souvik, Ishino, Masaho, Kobayashi, Nobumichi, Kuzuya, Mitsutaka, Paul, Shyamal Kumar, Wang, Yuan-Hong, Yamamoto, Dai, Zhou, Xuan   +8 more
core   +1 more source

Gig1, a novel antiviral effector involved in fish interferon response [PDF]

, 2014
Vertebrate interferon (IFN) response defenses against viral infection through the induction of hundreds of IFN-stimulated genes (ISGs). Most ISGs are conserved across vertebrates; however, little is known about the species-specific ISGs.
Chen, Chen, Gui, Jian-Fang, Jiang, Jun, Sun, Fan, Wang, Bing, Zhang, Jun, Zhang, YB (reprint author), Univ Chinese Acad Sci, Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Peoples R China., Zhang, Yi-Bing   +7 more
core   +1 more source

The destiny of the resistance/susceptibility against GCRV is controlled by epigenetic mechanisms in CIK cells [PDF]

Scientific Reports, 2017
AbstractHemorrhagic disease caused by grass carp reovirus (GCRV) has severely threatened the grass carp (Ctenopharyngodon idella) cultivation industry. It is noteworthy that the resistance against GCRV infection was reported to be inheritable, and identified at both individual and cellular levels.
Xueying Shang, Chunrong Yang, Quanyuan Wan, Youliang Rao, Jianguo Su   +4 more
openaire   +3 more sources

GCRV NS38 counteracts SVCV proliferation by intracellular antagonization during co-infection

Virologica Sinica, 2023
Viral co-infection has been found in animals; however, the mechanisms of co-infection are unclear. The abundance and diversity of viruses in water make fish highly susceptible to co-infection. Here, we reported a co-infection in fish, which resulted in reduced host lethality and illustrated the intracellular molecular mechanism of viral co-infection ...
Zhuo-Cong Li, Long-Feng Lu, Can Zhang, Xue-Li Wang, Jin-Feng Tong, Ke-Jia Han, Dan-Dan Chen, Xi-Yin Li, Li Zhou, Jian-Fang Gui, Shun Li   +10 more
openaire   +2 more sources