Results 41 to 50 of about 954 (183)

Identification, Virulence, and Molecular Characterization of a Recombinant Isolate of Grass Carp Reovirus Genotype I

open access: yesViruses, 2021
The hemorrhagic disease of grass carp (HDGC) caused by grass carp reovirus (GCRV) still poses a great threat to the grass carp industry. Isolation and identification of the GCRV genotype I (GCRV-I) has been rarely reported in the past decade.
Weiwei Zeng   +7 more
doaj   +1 more source

Type II Grass Carp Reovirus Rapidly Invades Grass Carp (Ctenopharyngodon idella) via Nostril–Olfactory System–Brain Axis, Gill, and Skin on Head

open access: yesViruses, 2023
Type II grass carp reovirus (GCRV-II) with high pathogenicity and infectivity causes severe hemorrhagic disease, which leads to extensive death in the grass carp and black carp aquaculture. However, the early invasion portal remains unclear.
Wentao Zhu   +5 more
doaj   +1 more source

Isolation, Identification, and Genomic Analysis of a Novel Reovirus from Healthy Grass Carp and Its Dynamic Proliferation In Vitro and In Vivo

open access: yesViruses, 2021
A new grass carp reovirus (GCRV), healthy grass carp reovirus (HGCRV), was isolated from grass carp in 2019. Its complete genome sequence was determined and contained 11 dsRNAs with a total size of 23,688 bp and 57.2 mol% G+C content, encoding 12 ...
Ke Zhang   +7 more
doaj   +1 more source

Assessment of listing and categorisation of animal diseases within the framework of the Animal Health Law (Regulation (EU) 2016/429): Spring Viraemia of Carp (SVC)

open access: yesEFSA Journal, Volume 21, Issue 10, October 2023., 2023
Abstract Spring Viraemia of Carp (SVC) was assessed according to the criteria of the Animal Health Law (AHL), in particular the criteria of Article 7 on disease profile and impacts, Article 5 on its eligibility to be listed, Annex IV for its categorisation according to disease prevention and control rules as in Article 9 and Article 8 for listing ...
EFSA Panel on Animal Health and Welfare (AHAW)   +28 more
wiley   +1 more source

Advances in research of biological functions of Isthmin‐1

open access: yesJournal of Cell Communication and Signaling, Volume 17, Issue 3, Page 507-521, September 2023., 2023
Graphical abstract The main biological functions of ISM1. Current studies on the biological functions of ISM1 focus on growth and development, metabolism, and anticancer treatment. During embryonic development, ISM1 is dynamically expressed in the zebrafish, African clawed frog, chick, mouse, and human, is associated with craniofacial malformations ...
Li Menghuan   +6 more
wiley   +1 more source

Structural and functional analysis of the small GTPase ARF1 reveals a pivotal role of its GTP-binding domain in controlling of the generation of viral inclusion bodies and replication of grass carp reovirus

open access: yesFrontiers in Immunology, 2022
Grass carp reovirus (GCRV) is the most pathogenic double-stranded (ds) RNA virus among the isolated aquareoviruses. The molecular mechanisms by which GCRV utilizes host factors to generate its infectious compartments beneficial for viral replication and ...
Jie Zhang   +7 more
doaj   +1 more source

Single‐cell transcriptome profiling reveals diverse immune cell populations and their responses to viral infection in the spleen of zebrafish

open access: yesThe FASEB Journal, Volume 37, Issue 6, June 2023., 2023
A comprehensive atlas of immune cell types in zebrafish was generated on the basis of single‐cell transcriptome profiling. The splenic leukocytes were collected from adult zebrafish that were administered with mock phosphate‐buffered saline, infected with spring viremia of carp virus (SVCV), and vaccinated with inactivated SVCV plus infected with ...
Chong‐Bin Hu   +7 more
wiley   +1 more source

Fish disease prevention via microbial dysbiosis‐associated biomarkers in aquaculture

open access: yesReviews in Aquaculture, Volume 15, Issue 2, Page 579-594, March 2023., 2023
Abstract Infectious diseases are a major burden in aquaculture, and represent a significant yield‐limiting factor in production that is costly to manage as well as a potential vector for zoonoses. Over the past decades, a range of new diseases have emerged, alongside increased levels of antibiotic resistance, thus heightening the need for improved ...
Julia Mougin, Alyssa Joyce
wiley   +1 more source

Characterization, Expression, and Ligand Binding of LGP2 and MDA5 in Largemouth Black Bass Micropterus salmoides (Lacepède, 1802)

open access: yesAquaculture Research, Volume 2023, Issue 1, 2023., 2023
Melanoma differentiation‐associated gene 5 (MDA5) and the laboratory of genetics and physiology 2 (LGP2) are family members of retinoic acid‐inducible gene I (RIG‐I)‐like receptors (RLRs), which play important roles in the immune response against pathogens invasion.
Xiangyu Pi   +6 more
wiley   +1 more source

Bid-deficient fish delay grass carp reovirus (GCRV) replication and attenuate GCRV-triggered apoptosis

open access: yesOncotarget, 2017
Bid, BH3-interacting domain death agonist, is a pro-apoptotic BH3-only member of Bcl-2 family, playing an important role in apoptosis. In the study, Bid genes from grass carp (Ctenopharyngodon idellus) and rare minnow (Gobiocypris rarus), named CiBid and GrBid, were cloned and analyzed.
He, Libo   +7 more
openaire   +2 more sources

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