Results 21 to 30 of about 954 (183)

Grass carp catalase inhibits GCRV replication through ROS scavenging-mediated immune suppression and autophagy [PDF]

Virulence
Catalase (CAT) is a key antioxidant enzyme that eliminates reactive oxygen species (ROS), thereby protecting organisms from oxidative stress and maintaining cellular homeostasis.
Xuyang Wang, Xiaowen Zou, Linlin Liu, Xinyu Liang, Hanyue Wang, Cheng Yang, Yongming Li, Lanjie Liao, Zuoyan Zhu, Yaping Wang, Jingjing Zhao, Libo He   +11 more
doaj   +2 more sources

The destiny of the resistance/susceptibility against GCRV is controlled by epigenetic mechanisms in CIK cells [PDF]

Scientific Reports, 2017
Hemorrhagic disease caused by grass carp reovirus (GCRV) has severely threatened the grass carp (Ctenopharyngodon idella) cultivation industry. It is noteworthy that the resistance against GCRV infection was reported to be inheritable, and identified at ...
Xueying Shang, Youliang Rao, Chunrong Yang, Quanyuan Wan, Jianguo Su   +4 more
core   +4 more sources

Cloning of Grass Carp Chemokine XC Receptor 1 (XCR1) Gene and Evaluation of Its Expression in Various Organs after GCRV Infection

Fishes, 2022
Interaction between the chemokine receptor XCR1 and its ligand is closely related to the immune function in animals; however, there are only a few reports on role of XCR1 in the immune system of fish. We aimed to analyze the expression of XCR1 in various
Hailuo Yu, Yi Liu, Tiaoyi Xiao, Hongquan Wang, Baohong Xu   +4 more
doaj   +2 more sources

Coordination of oxysterol binding protein 1 and VAP-A/B modulates the generation of cholesterol and viral inclusion bodies to promote grass carp reovirus replication [PDF]

Frontiers in Immunology
Similar to other RNA viruses, grass carp reovirus, the causative agent of the hemorrhagic disease, replicates in cytoplasmic viral inclusion bodies (VIBs), orchestrated by host proteins and lipids.
Jia Qi Li, Jia Qi Li, Jie Zhang, Jie Zhang, Yang Chen, Yang Chen, Tao Le, Ming Xian Chang, Ming Xian Chang   +8 more
doaj   +2 more sources

Effect of Heat Shock Treatment on the Virulence of Grass Carp Reovirus in Rare Minnow Gobiocypris rarus [PDF]

Viruses
The mode and outcome of fish–virus interactions are influenced by many abiotic factors, among which water temperature is especially important in poikilothermic fish.
Qinwei Ni, Yanchang Fan, Simin Xiao, Liqun Lu   +3 more
doaj   +2 more sources

Preliminary study of BF/C2 on immune mechanism of grass carp against GCRV infection. [PDF]

BMC Genomics
BF/C2 is a crucial molecule in the coagulation complement cascade pathway and plays a significant role in the immune response of grass carp through the classical, alternative, and lectin pathways during GCRV infection.
Wei Y, Xiao Y, Liu Q, Du Z, Xiao T.
europepmc   +5 more sources

Additional file 1: Table S1. of Prediction of GCRV virus-host protein interactome based on structural motif-domain interactions [PDF]

BMC Bioinformatics, 2017
Information for predicted motifs information of proteins in GCRV GD108 based on 3did database.
Yaping Wang (289641), Aidi Zhang, Wang, Yaping, Yaping Wang, Zhang, Aidi, Aidi Zhang (1880896), Libo He (3760216), Libo He, He, Libo   +8 more
core   +4 more sources

Characterization of the NFAT Gene Family in Grass Carp (Ctenopharyngodon idellus) and Functional Analysis of NFAT1 During GCRV Infection

Fishes
Nuclear factors of activated T cells (NFATs) are pivotal regulatory factors of immune responses, primarily by modulating T cell activity and regulating inflammatory cytokine gene transcription.
Yao Shen, Yitong Zhang, Chen Chen, Shitao Hu, Jia Liu, Yiling Zhang, Tiaoyi Xiao, Baohong Xu, Qiaolin Liu   +8 more
doaj   +2 more sources

Comparative Transcriptomics Analysis Reveals Unique Immune Response to Grass Carp Reovirus Infection in Barbel Chub (Squaliobarbus curriculus) [PDF]

Biology
Grass carp (Ctenopharyngodon idella) and barbel chub (Squaliobarbus curriculus)—both Leuciscinae subfamily species—demonstrate differences in grass carp reovirus (GCRV) infection resistance.
Yuhong Huang, Xiaodong Wang, Zhao Lv, Xudong Hu, Baohong Xu, Hong Yang, Tiaoyi Xiao, Qiaolin Liu   +7 more
doaj   +2 more sources

Differences in responses of grass carp to different types of grass carp reovirus (GCRV) and the mechanism of hemorrhage revealed by transcriptome sequencing

BMC Genomics, 2017
Background Grass carp is an important farmed fish in China that is affected by serious disease, especially hemorrhagic disease caused by grass carp reovirus (GCRV).
Libo He, Aidi Zhang, Yongyan Pei, Pengfei Chu, Yongming Li, Rong Huang, Lanjie Liao, Zuoyan Zhu, Yaping Wang   +8 more
doaj   +2 more sources