Results 11 to 20 of about 1,339 (193)

Integrative transcriptome analysis reveals alternative polyadenylation potentially contributes to GCRV early infection [PDF]

Frontiers in Microbiology, 2023
IntroductionGrass carp reovirus (GCRV), a member of the Aquareovirus genus in the Reoviridae family, is considered to be the most pathogenic aquareovirus. Productive viral infection requires extensive interactions between viruses and host cells. However,
Sheng Tan, Jie Zhang, Jie Zhang, Yonglin Peng, Wenfei Du, Jingxuan Yan, Qin Fang   +6 more
doaj   +4 more sources

Preliminary study of BF/C2 on immune mechanism of grass carp against GCRV infection [PDF]

BMC Genomics
BF/C2 is a crucial molecule in the coagulation complement cascade pathway and plays a significant role in the immune response of grass carp through the classical, alternative, and lectin pathways during GCRV infection.
Yuling Wei, Yu Xiao, Qiaolin Liu, Zongjun Du, Tiaoyi Xiao   +4 more
doaj   +4 more sources

First Investigation of Grass Carp Reovirus (GCRV) Infection in Amphioxus: Insights into Pathological Effects, Transmission, and Transcriptomic Responses [PDF]

Viruses
Amphioxus belongs to the subphylum Cephalochordata and occupies a transitional position in evolution between invertebrates and vertebrates. Due to the lack of viruses suitable for immunostimulation in amphioxus, this study for the first time explored the
Jingyuan Lin, Meng Yang, Huijuan Yang, Guangdong Ji, Zhenhui Liu   +4 more
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Antibodies against outer-capsid proteins of grass carp reovirus expressed in E. coli are capable of neutralizing viral infectivity [PDF]

Virology Journal, 2011
Background Grass carp reovirus (GCRV), which causes severe infectious outbreaks of hemorrhagic disease in aquatic animals, is a highly pathogenic agent in the Aquareovirus genus of family Reoviridae.
Sun Xiaoyun, Shao Ling, Fang Qin
doaj   +4 more sources

Grass carp SERPINA1 inhibits GCRV infection through degrading CF2

Frontiers in Immunology, 2022
SERPINA1, a member of the serine protease inhibitor family, plays a role in viral infection and inflammation by regulating the activities of serine and cysteine proteases.
Yangyang Li, Yangyang Li, Liangming Chen, Liangming Chen, Rong Huang, Yangyu Li, Yangyu Li, Cheng Yang, Bin Gui, Bin Gui, Yongming Li, Lanjie Liao, Zuoyan Zhu, Yaping Wang, Yaping Wang   +14 more
doaj   +3 more sources

Characterization of grass carp reovirus minor core protein VP4 [PDF]

Virology Journal, 2012
Background Grass Carp Reovirus (GCRV), a tentative member in the genus Aquareovirus of family Reoviridae, contains eleven segmented (double-stranded RNA) dsRNA genome which encodes 12 proteins.
Yan Liming, Guo Hong, Sun Xiaoyun, Shao Ling, Fang Qin   +4 more
doaj   +4 more sources

Identification and characterization of a novel reovirus strain isolated fromgrass carp (Ctenopharyngodon idella) [PDF]

Virology Journal
Background Grass carp (Ctenopharyngodon idella) hemorrhagic disease (GCHD) is a devastating disease that leads to substantial economic losses in the freshwater aquaculture industry.
Weiguang Kong, Guangyi Ding, Qiushi Zhang, Xinjie Yuan, Yuchao Zhu, Liyuan Ma, Chang Cai, Yong Shi, Qianqian Zhang, Zhen Xu   +9 more
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Autophagy Inhibits Grass Carp Reovirus (GCRV) Replication and Protects Ctenopharyngodon idella Kidney (CIK) Cells from Excessive Inflammatory Responses after GCRV Infection [PDF]

Biomolecules, 2020
Autophagy is an essential and highly conserved process in mammals, which is critical to maintaining physiological homeostasis, including cell growth, development, repair, and survival.
Pengfei Chu, Libo He, Rong Huang, Lanjie Liao, Yongming Li, Zuoyan Zhu, Wei Hu, Yaping Wang   +7 more
doaj   +3 more sources

Grass carp reovirus VP4 manipulates TOLLIP to degrade STING for inhibition of IFN production [PDF]

Journal of Virology
Although fish possess an effective interferon (IFN) system to defend against viral infection, grass carp reovirus (GCRV) still causes epidemic hemorrhagic disease and tremendous economic loss in grass carp.
Yang-Yang Wang, Xue-Li Wang, Zhuo-Cong Li, Can Zhang, Xiao Xu, Bao-Jie Cui, Meng-Ze Tian, Chu-Jing Zhou, Na Xu, Yue Wu, Xiao-Li Yang, Dan-Dan Chen, Long-Feng Lu, Shun Li   +13 more
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A Novel Subunit Vaccine Based on Outer Capsid Proteins of Grass Carp Reovirus (GCRV) Provides Protective Immunity against GCRV Infection in Rare Minnow (Gobiocypris rarus) [PDF]

Pathogens, 2020
The grass carp hemorrhagic disease, caused by the grass carp reovirus (GCRV), has resulted in severe economic losses in the aquaculture industry in China. VP4 and VP35 are outer capsid proteins of GCRV and can induce an immune response in the host. Here,
Changyong Mu, Vikram N. Vakharia, Yong Zhou, Nan Jiang, Wenzhi Liu, Yan Meng, Yiqun Li, Mingyang Xue, Jieming Zhang, Lingbing Zeng, Qiwang Zhong, Yuding Fan   +11 more
doaj   +3 more sources