Results 121 to 130 of about 25,935 (265)

Generation and Characterization of a Human/Mouse Chimeric GD2-Mimicking Anti-Idiotype Antibody Ganglidiximab for Active Immunotherapy against Neuroblastoma.

PLoS ONE, 2016
Vaccination with proteins mimicking GD2 that is highly expressed on neuroblastoma (NB) cells is a promising strategy in treatment of NB, a pediatric malignancy with poor prognosis.
Christin Eger, Nikolai Siebert, Diana Seidel, Maxi Zumpe, Madlen Jüttner, Sven Brandt, Hans-Peter Müller, Holger N Lode   +7 more
doaj   +1 more source

Building the analytical response in frequency domain of AC biased bolometers Application to Planck/HFI

, 2016
Context: Bolometers are high sensitivity detector commonly used in Infrared astronomy. The HFI instrument of the Planck satellite makes extensive use of them, but after the satellite launch two electronic related problems revealed critical.
Montier, Ludovic, Sauvé, Alexandre
core   +3 more sources

GD2‐directed CAR‐T cells in combination with HGF‐targeted neutralizing antibody (AMG102) prevent primary tumor growth and metastasis in Ewing sarcoma [PDF]

, 2019
Manish Charan, Piyush Dravid, Maren Cam, Anthony Audino, Amy C. Gross, Michael Arnold, Ryan D. Roberts, Timothy P. Cripe, Alexander Pertsemlidis, Peter J. Houghton, Hakan Çam   +10 more
openalex   +1 more source

Supplementary Figure Legend from Activated Natural Killer Cells in Combination with Anti-GD2 Antibody Dinutuximab Improve Survival of Mice after Surgical Resection of Primary Neuroblastoma

, 2023
Wesley E. Barry, Jeremy R. Jackson, Grace E. Asuelime, Hongwei Wu, Jianping Sun, Zesheng Wan, Jemily Malvar, Michael A. Sheard, Larry Wang, Robert C. Seeger, Eugene S. Kim   +10 more
openalex   +1 more source

Prospects of anti-GD2 immunotherapy for retinoblastoma

Frontiers in Immunology
Retinoblastoma is the most common type of eye tumor in infants and children. Current treatments for retinoblastoma include intravenous chemotherapy, intra-arterial chemotherapy, intravitreal chemotherapy, cryotherapy, radiotherapy, and surgery.
Xinlong Zhang, Xinlong Zhang, Xinlong Zhang, Wulin You, Wulin You, Yuntao Wang, Yuntao Wang, Yuntao Wang, Rebeka Dejenie, Rebeka Dejenie, Chenhao Wang, Yan Huang, Yan Huang, Yan Huang, Jingjing Li, Jingjing Li, Jingjing Li, Jingjing Li   +17 more
openaire   +3 more sources

Latin American Consensus on the Use of Anti-GD2 Monoclonal Antibody Therapy in Patients With High-Risk Neuroblastoma

JCO Global Oncology
PURPOSETo develop a Latin American expert consensus to support, guide, and accelerate the approval and equitable access to anti-GD2 immunotherapy for patients with high-risk neuroblastoma (HR-NB) in the region. Survival rates for HR-NB have improved with
Gabriela I. Villanueva, Sandra Alarcón, Diana Bonilla, Alejandra Casanovas, Mauricio Chaparro, Marcelo D. Coirini, Guido Felizzia, Diego Figueredo, Soad Fuentes-Alabi, Sima Ferman, Simone Franco, Mercedes Garcia Lombardi, Félix Gaytan Morales, Lauro J. Gregianin, Óscar González Ramella, Nathalia Halley, Camila Hashimoto, Arissa Ikeda, Scott Howard, Luis E. Juárez Villegas, Fabiana Morosini, Alberto Olaya Vargas, Vicente Odone-Filho, Nevicolino Pereira de Carvalho Filho, Catalina Peters, Veronica Pérez, Martín Pérez García, Agustina Pollono, Roy Rosado, Lourdes Romero, Haydeé del Pilar Salazar Rosales, Beatriz Silva, Victoria Sobrero, Delia P. Streitenberger, Diana Valencia, Mariana Varela, Milena Villarroel   +36 more
doaj   +1 more source

Electronic structure of gadolinium complexes in ZnO in the GW approximation

, 2017
The role of intrinsic defects has been investigated to determine binding energies and the electronic structure of Gd complexes in ZnO. We use density-functional theory and the GW method to show that the presence of vacancies and interstitials affect the ...
Frauenheim, Th., Rosa, A. L.
core   +1 more source

NKT cells coexpressing a GD2-specific chimeric antigen receptor and IL15 show enhanced in vivo persistence and antitumor activity against neuroblastoma

, 2021
Y. Chen, W. Huang, Jianxiang Jin, B. Savoldo, Gabriel A Barragan, Detian Liu, L.S. Metelitsa, X. Xu, M. Wood, A.N. Courtney, L. Guo, B. Liu, Erika J. di Pierro, H. Ngai, G. Dotti, A. Heczey, J. Hicks   +16 more
openalex   +1 more source

A Backwards Approach to GD2 Immunofluorescence in Human Neuroblastoma Tissue Samples: From Staining to Slicing

Cells
Background: The disialoganglioside GD2, located at the plasma membrane, is selectively overexpressed in various solid tumors, where it contributes to tumor growth and the development of an aggressive tumor phenotype.
Sara Peggion, Clara Volz, Magdalena Trochimiuk, Isabelle Ariane Bley, Júlia Ramos, Konrad Reinshagen, Laia Pagerols Raluy   +6 more
doaj   +1 more source

Targeting both GD2 and B7-H3 using bispecific antibody improves tumor selectivity for GD2-positive tumors

AbstractObjectivesDisialoganglioside 2 (GD2), overexpressed by cancers such as melanoma and neuroblastoma, is a tumor antigen for targeted therapy. The delivery of conventional IgG antibody technologies targeting GD2 is limited clinically by its co-expression on nerves that contributes to toxicity presenting as severe neuropathic pain.
Zachary T. Rosenkrans, Amy K. Erbe, Nathan B. Clemons, Arika S. Feils, Yadira Medina-Guevara, Justin J. Jeffery, Todd E. Barnhart, Jonathan W. Engle, Paul M. Sondel, Reinier Hernandez   +9 more
openaire   +2 more sources