Results 21 to 30 of about 37,648 (242)
Molecular Therapy: Methods & Clinical Development, 2020 Glial cell line-derived neurotrophic factor (GDNF) supports function and survival of dopamine neurons that degenerate in Parkinson’s disease (PD). Ectopic delivery of GDNF in clinical trials to treat PD is safe but lacks significant therapeutic effect ...
Giorgio Turconi +6 more
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تأثیر چهار هفته تمرین هوازی بر بیان ژن فاکتور تغذیه‌ای مشتق‌شده از سلول‌های گلیال، TNF-α و عوامل شناختی در هیپوکمپ رت‌های مبتلا به بیماری آلزایمر القاشده با آمیلویید بتا [PDF]
فیزیولوژی ورزشی, 2021 زمینه و هدف : بیماری آلزایمر شایعترین شکل زوال عقل است و آمیلوئیدبتا نقشی در بیماری زایی آن ایفا میکنند. در سالهای اخیر ورزش منظم به عنوان یکی از سازوکارهای غیردارویی مهم برای مقابل با بیماری آلزایمر مطرح شده است.
پیمان قاسمی +3 more
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Neurobiology of Disease, 2006 The effect of selective injury to dopaminergic neurons on the expression of glial cell line-derived neurotrophic factor (GDNF) was examined in substantia nigra cell cultures.
Ana Saavedra +4 more
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Brain Sciences, 2023 Sleep disturbances are the most prevalent non-motor symptoms in the preclinical stage of Parkinson’s disease (PD). Adenosine, glial-derived neurotrophic factor (GDNF), and associated neurotransmitters are crucial in the control of sleep arousal.
Li Wang +4 more
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SorLA Controls Neurotrophic Activity by Sorting of GDNF and Its Receptors GFRα1 and RET
Cell Reports, 2013 Glial cell-line-derived neurotrophic factor (GDNF) is a potent neurotrophic factor that has reached clinical trials for Parkinson’s disease. GDNF binds to its coreceptor GFRα1 and signals through the transmembrane receptor tyrosine kinase RET, or RET ...
Simon Glerup +13 more
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Медицинская иммунология, 2021 Traumatic brain injury is the most common cause of death and disability in young people including sport athletes and soldiers, people under 45 years of age in the industrialized countries, representing a growing health problem in developing countries, as
E. A. Korneva +4 more
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Six month delivery of GDNF from PLGA/vitamin E biodegradable microspheres after intravitreal injection in rabbits [PDF]
, 2017 Local long-term delivery of glial cell line derived neurotrophic factor (GDNF) from vitamin E/poly-lactic-co-glycolic acid microspheres (MSs) protects retinal ganglion cells in an animal model of glaucoma for up to 11 weeks. However, the pharmacokinetics
Prieto Calvo, Esther +26 more
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Expression and function of GDNF family ligands and their receptors by human immune cells [PDF]
, 2004 GDNF (glial cell line-derived neurotrophic factor) und NTN (Neurturin), die zwei zuerst beschriebenen Liganden der GDNF-Familie, fungieren als Überlebens- und Entwicklungsfaktoren für definierte Populationen von zentralen und peripheren Neuronen.
Vargas, Vivian
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Klinik Psikiyatri Dergisi, 2023 INTRODUCTION: The neurodevelopmental hypothesis of schizophrenia suggests that alterations of glial fibrillary acidic protein (GFAP) and glial cell line-derived neurotrophic factor (GDNF) functions may play a role in the pathogenesis of schizophrenia ...
İhsan Çetin +4 more
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Drug Design, Development and Therapy, 2020 Yahan Zhang,1 Qiushi Gao,1 Ziyi Wu,1 Hang Xue,1 Bo Liu,2 Ping Zhao1 1Department of Anesthesiology, Shengjing Hospital, China Medical University, Shenyang, People’s Republic of China; 2Department of Animal Laboratory of Experimental Research Center,
Zhang Y +5 more
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