Results 71 to 80 of about 1,893,955 (220)

KDM2 Family Members are Regulated by HIF-1 in Hypoxia

open access: yesCells, 2017
Hypoxia is not only a developmental cue but also a stress and pathological stimulus in many human diseases. The response to hypoxia at the cellular level relies on the activity of the transcription factor family, hypoxia inducible factor (HIF).
Michael Batie   +3 more
doaj   +1 more source

Acute phase induction of the human C-reactive protein gene in transgenic mice

open access: yes, 1987
Regulation of human C-reactive protein ...
ARCONE, Rosaria
core  

Auxin-regulated gene expression

open access: yesPhilosophical Transactions of the Royal Society of London. B, Biological Sciences, 1986
Abstract During the 1960s a wide range of studies provided an information base that led to the suggestion that auxin-regulated cell processes - especially cell elongation - may be mediated by auxin-regulated gene expression. Indirect evidence from our work, based on the influence of inhibitors of RNA synthesis (e.g. actinomycin D) and
J L, Key   +7 more
openaire   +3 more sources

Identification of hepatocyte nuclear proteins wich interact with the human C-reactive promoter

open access: yes, 1989
Regulation of Human C-reactive protein gene ...
Ciliberto G   +5 more
core  

Insights into the regulation of intrinsically disordered proteins in the human proteome by analyzing sequence and gene expression data [PDF]

open access: yes, 2009
Background: Disordered proteins need to be expressed to carry out specified functions; however, their accumulation in the cell can potentially cause major problems through protein misfolding and aggregation.
Edwards, Y.J.K.   +11 more
core   +1 more source

Balancing noise and plasticity in gene expression

open access: yes, 2011
Coupling the control of expression stochasticity (noise) with the capacity to expression change (plasticity) can constrain gene function and limit adaptation. Which factors contribute then to modulate this coupling?
Juan F. Poyatos, Djordje Bajic
core  

GSTCD and INTS12 Regulation and Expression in the Human Lung [PDF]

open access: yes, 2013
Genome-Wide Association Study (GWAS) meta-analyses have identified a strong association signal for lung function, which maps to a region on 4q24 containing two oppositely transcribed genes: glutathione S-transferase, C-terminal domain containing (GSTCD ...
Swan, Caroline   +125 more
core   +1 more source

Enhancer remodeling promotes tumor-initiating activity in NRF2-activated non-small cell lung cancers

open access: yesNature Communications, 2020
Aberrant activation of NRF2 in cancer cells contributes to tumorigenicity and therapeutic resistance. Here, the authors show that NRF2 cooperates with CEBPB and remodels enhancers to confer tumor-initiating activity on NRF2- activated non-small cell lung
Keito Okazaki   +20 more
doaj   +1 more source

Real-time transcriptional profiling of cellular and viral gene expression during lytic cytomegalovirus infection. [PDF]

open access: yes, 2012
During viral infections cellular gene expression is subject to rapid alterations induced by both viral and antiviral mechanisms. In this study, we applied metabolic labeling of newly transcribed RNA with 4-thiouridine (4sU-tagging) to dissect the real ...
Lisa Marcinowski   +46 more
core   +1 more source

Efficient analysis of mammalian polysomes in cells and tissues using Ribo Mega-SEC

open access: yeseLife, 2018
We describe Ribo Mega-SEC, a powerful approach for the separation and biochemical analysis of mammalian polysomes and ribosomal subunits using Size Exclusion Chromatography and uHPLC.
Harunori Yoshikawa   +6 more
doaj   +1 more source

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