Human aldolase C: gene transcriptional regulation and protein functional role
, 2011 Aldolase C is the brain-specific aldolase isoenzyme. In the human brain, aldolase C messenger and protein are expressed in a stripe-like pattern in the Purkinje cells of the cerebellum, in the inferior olives and in the Goll and Burdach nuclei of the ...
Serio, Laura
core
Expression and regulation of the Escherichia coli O157:H7 effector proteins NleH1 and NleH2 [PDF]
, 2012 E. coli O157 carries two genes encoding the effector proteins NleH1 and NleH2 which are 87% identical. Despite the similarity between the proteins, the promoter regions upstream of the genes encoding the effectors are more divergent suggesting that the ...
Mitchell, T.J. +6 more
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Global regulation of gene expression [PDF]
Proceedings of the National Academy of Sciences, 2000 Microorganisms such as Escherichia coli live in environments subject to rapid changes in the availability of the carbon and nitrogen compounds necessary to provide energy and building blocks for the synthesis of cell material. Their survival depends on their ability to regulate the expression of genes coding for the enzymes and transport proteins ...
openaire +2 more sources
Transcriptional regulation of the human c-myc gene
, 1988 The involvement of c-myc in the genesis of animal neoplasia is now well documented for several systems. In order to define the precise role played by the myc gene in tumorigenesis, a better understanding of the normal regulation of myc expression is ...
Wilkie, N M +3 more
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Gene Structure, cDNA Sequence, and mRNA Distribution [PDF]
, 1994 The rat HNF-3 (hepatocyte nuclear factor 3) gene family encodes three transcription factors known to be important in the regulation of gene expression in liver and lung.
Schütz, Günther +3 more
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Tetracycline aptamer-controlled regulation of pre-mRNA splicing in yeast
, 2007 Splicing of pre-mRNA is a critical step in mRNA maturation and disturbances cause several genetic disorders. We apply the synthetic tetracycline (tc)-binding riboswitch to establish a gene expression system for conditional tc-dependent control of pre ...
Weigand, Julia E. +3 more
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Androgen-induced rhox homeobox genes modulate the expression of AR-regulated genes [PDF]
, 2010 Rhox5, the founding member of the reproductive homeobox on the X chromosome (Rhox) gene cluster, encodes a homeodomain-containing transcription factor that is selectively expressed in Sertoli cells, where it promotes the survival of male germ cells ...
Hu, Z.Y. +7 more
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LEM-3 is a midbody-tethered DNA nuclease that resolves chromatin bridges during late mitosis
Nature Communications, 2018 Chromosome segregation and genome maintenance require the removal of DNA bridges that link chromosomes just before cells divide. Here the authors show that the LEM-3/Ankle1 nuclease processes DNA bridges before cells divide and define a previously ...
Ye Hong +9 more
doaj +1 more source
Transcription regulation of the Escherichia coli pcnB gene coding for poly(A) polymerase I: roles of ppGpp, DksA and sigma factors [PDF]
, 2010 Poly(A) polymerase I (PAP I), encoded by the pcnB gene, is a major enzyme responsible for RNA polyadenylation in Escherichia coli, a process involved in the global control of gene expression in this bacterium through inXuencing the rate of transcript ...
Grzegorz Węgrzyn +11 more
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SPOP E3 Ubiquitin Ligase Adaptor Promotes Cellular Senescence by Degrading the SENP7 deSUMOylase
Cell Reports, 2015 The SPOP gene, which encodes an E3 ubiquitin ligase adaptor, is frequently mutated in a number of cancer types. However, the mechanisms by which SPOP functions as a tumor suppressor remain poorly understood.
Hengrui Zhu +9 more
doaj +1 more source