Results 161 to 170 of about 2,701,308 (189)
Some of the next articles are maybe not open access.
British Medical Bulletin, 1991
A fundamental tenet of biology is that the phenotype of an organism is ultimately determined by its complement of genes. In multicellular organisms, it is the regulated pattern of expression of genes which determines the proliferation and differentiation of individual cell lineages and hence establishes the adult phenotype.
openaire +2 more sources
A fundamental tenet of biology is that the phenotype of an organism is ultimately determined by its complement of genes. In multicellular organisms, it is the regulated pattern of expression of genes which determines the proliferation and differentiation of individual cell lineages and hence establishes the adult phenotype.
openaire +2 more sources
Regulation of KiSS1 gene expression
Peptides, 2009Kisspeptins are the protein products encoded by KiSS1 gene, an important tumor metastatic suppressor and pivotal master hormone of puberty. Although KiSS1 gene is expressed in both central and peripheral tissues, the molecular mechanisms that determine the temporal and spatial expression of KiSS1 gene are not well understood.
Dali, Li, Weishi, Yu, Mingyao, Liu
openaire +2 more sources
New England Journal of Medicine, 1994
Genetics is a language with rules of composition that give the tissues of the body their special traits. These rules govern the activation of particular subgroups of genes, which determine not only the unique characteristics of a cell type but also whether it remains quiescent, divides, or dies. The timing of gene activation is very important. If genes
openaire +2 more sources
Genetics is a language with rules of composition that give the tissues of the body their special traits. These rules govern the activation of particular subgroups of genes, which determine not only the unique characteristics of a cell type but also whether it remains quiescent, divides, or dies. The timing of gene activation is very important. If genes
openaire +2 more sources
Osmotic regulation of gene expression
The FASEB Journal, 1996Cells react to increased osmolality with numerous changes in gene expression. The specific genes affected differ between species, but the known osmoprotective effects of the gene products are remarkably similar, particularly with regard to cellular accumulation of compatible organic os‐ molytes. Here we concentrate on the molecular
M B, Burg, E D, Kwon, D, Kültz
openaire +2 more sources
Regulation of Cytokine Gene Expression
Annual Review of Immunology, 1988Following the isolation and characterization of many cytokine genes, we began to understand the mechanisms regulating cytokine gene expression. Needless to say, understanding the mechanisms by which induction of gene expression occurs in a transient, cell type-specific manner in response to extracellular inducers is a central issue in eukaryotic ...
openaire +2 more sources
Regulation Of Neuropeptide Gene Expression
Annual Review of Neuroscience, 1990Understanding of the mechanisms of neuropeptide gene regulation has increased dramatically in the past 5 years. In large part, this increased understanding has resulted from advances in the technology of introducing reporter genes into intact cells in culture.
openaire +2 more sources
Regulating gene expression in gene therapy
Trends in Biotechnology, 1993Ensuring that expression of introduced genes is both safe and effective necessitates directing expression to the appropriate tissue, at levels which produce a therapeutic effect. Extensive research is under way to elucidate the mechanisms and genetic elements involved in regulating expression. With the need to correlate expression levels and phenotypic
openaire +2 more sources
Regulation of opioid gene expression
Peptides, 1983Opioid peptides are synthesized in the form of large precursors, which contain the information for more than one biologically active peptide. Using recombinant DNA technology, three opioid precursors have been sequenced: pro-opiomelanocortin (POMC), proenkephalin and prodynorphin.
O, Civelli +6 more
openaire +2 more sources
Repetitive DNA regulates gene expression
Science, 2023Short tandem repeats affect gene expression by binding regulatory ...
openaire +2 more sources
Regulation of histone gene expression
Current Opinion in Cell Biology, 1992Histone genes are expressed during the S phase of the cell cycle. Control is at multiple levels and is mediated by the integration of regulatory signals in response to cell-cycle progression and the onset of differentiation. Much work has been carried out on the H4 gene promoter, which appears to be organized into a series of distinct regulatory ...
Stein, Gary S. +3 more
openaire +3 more sources