Results 111 to 120 of about 261,824 (309)
Correction to: wpLogicNet: logic gate and structure inference in gene regulatory networks [PDF]
, 2023 openalex +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Gene regulatory networks and delay differential equations
Electronic Journal of Differential Equations, 2005 This paper suggests a mathematical framework to study gene regulatory networks with time-delay effects, which is based on delay differential equations. An essential feature of the gene regulatory networks is their ``almost Boolean'' structure, where the ...
Arcady Ponosov
doaj
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Developmental transcriptomics of Chinese cordyceps reveals gene regulatory network and expression profiles of sexual development-related genes [PDF]
, 2019 Xiao Li +8 more
openalex +1 more source
Quasi-periodic Solutions for a Three-dimensional System in Gene Regulatory Network
, 2023 Olga Kozlovska, Inna Samuilik
openalex +1 more source
Evaluation of protein’s interaction and the regulatory network of some drought-responsive genes in Canola under drought and re-watering conditions [PDF]
, 2023 Maryam Pasandideh Arjmand +3 more
openalex +1 more source