Results 1 to 10 of about 614,030 (339)

Virus‐induced gene silencing database for phenomics and functional genomics in Nicotiana benthamiana [PDF]

Plant Direct, 2018
Virus‐induced gene silencing (VIGS) is an important forward and reverse genetics method for the study of gene function in many plant species, especially Nicotiana benthamiana.
Muthappa Senthil‐Kumar, Mingyi Wang, Junil Chang, Venkategowda Ramegowda, Olga del Pozo, Yule Liu, Vanthana Doraiswamy, Hee‐Kyung Lee, Choong‐Min Ryu, Keri Wang, Ping Xu, Joyce Van Eck, Suma Chakravarthy, Savithramma P. Dinesh‐Kumar, Gregory B. Martin, Kirankumar S. Mysore   +15 more
doaj   +3 more sources

Prior Biological Knowledge Improves Genomic Prediction of Growth-Related Traits in Arabidopsis thaliana

Frontiers in Genetics, 2021
Prediction of growth-related complex traits is highly important for crop breeding. Photosynthesis efficiency and biomass are direct indicators of overall plant performance and therefore even minor improvements in these traits can result in significant ...
Muhammad Farooq, Muhammad Farooq, Aalt D. J. van Dijk, Aalt D. J. van Dijk, Harm Nijveen, Mark G. M. Aarts, Willem Kruijer, Thu-Phuong Nguyen, Shahid Mansoor, Dick de Ridder   +9 more
doaj   +1 more source

Silence of the genes [PDF]

Proceedings of the National Academy of Sciences, 2004
The genomes of many species, including man, have been laid bare with hundreds of known and thousands of unknown genes. A major challenge in present day biology is to decipher the molecular function of the unknown genes. Gene knockout by homologous recombination has proven to be very useful but is laborious and expensive.
Inder M. Verma, Amiel Yanai, Oded Singer
openaire   +3 more sources

Comprehensive Mechanism of Gene Silencing and Its Role in Plant Growth and Development

Frontiers in Plant Science, 2021
Gene silencing is a negative feedback mechanism that regulates gene expression to define cell fate and also regulates metabolism and gene expression throughout the life of an organism.
Ahmed H. El-Sappah, Ahmed H. El-Sappah, Ahmed H. El-Sappah, Kuan Yan, Kuan Yan, Qiulan Huang, Qiulan Huang, Qiulan Huang, Md. Monirul Islam, Quanzi Li, Quanzi Li, Yu Wang, Yu Wang, Muhammad Sarwar Khan, Xianming Zhao, Xianming Zhao, Reyazul Rouf Mir, Jia Li, Jia Li, Khaled A. El-Tarabily, Khaled A. El-Tarabily, Manzar Abbas, Manzar Abbas   +22 more
doaj   +1 more source

Global Analysis of RNA-Dependent RNA Polymerase-Dependent Small RNAs Reveals New Substrates and Functions for These Proteins and SGS3 in Arabidopsis

Non-Coding RNA, 2021
RNA silencing pathways control eukaryotic gene expression transcriptionally or posttranscriptionally in a sequence-specific manner. In RNA silencing, the production of double-stranded RNA (dsRNA) gives rise to various classes of 20–24 nucleotide (nt ...
Xia Hua, Nathan D. Berkowitz, Matthew R. Willmann, Xiang Yu, Eric Lyons, Brian D. Gregory   +5 more
doaj   +1 more source

Gene Activation and Gene Silencing [PDF]

Plant Physiology, 2001
Twenty-five years ago the field of eukaryotic gene regulation was in its infancy. Paradigms driving experiments came primarily from work with prokaryotes and the phage that infected them (12). These paradigms, pioneered by Jacob and Monod, were that genes contained promoter sequences to which ...
Hervé Vaucheret, Vicki L. Chandler
openaire   +3 more sources

Dynamic spreading of chromatin-mediated gene silencing and reactivation between neighboring genes in single cells

eLife, 2022
In mammalian cells genes that are in close proximity can be transcriptionally coupled: silencing or activating one gene can affect its neighbors. Understanding these dynamics is important for natural processes, such as heterochromatin spreading during ...
Sarah Lensch, Michael H Herschl, Connor H Ludwig, Joydeb Sinha, Michaela M Hinks, Adi Mukund, Taihei Fujimori, Lacramioara Bintu   +7 more
doaj   +1 more source

Pygmy MicroRNA: Surveillance Cops in Therapy Kingdom

Molecular Medicine, 2016
MicroRNAs (miRNAs) are well preserved in every animal. These pygmy-sized (21–23 nt) noncoding RNAs scattered in the genome are responsible for micromanaging versatile gene regulation.
Utpal Bhadra, Pradipta Patra, Jagamohan Chhatai, Manika Pal-Bhadra   +3 more
doaj   +1 more source

Genomic prediction in plants: opportunities for ensemble machine learning based approaches [version 2; peer review: 1 approved, 2 approved with reservations]

F1000Research, 2023
Background: Many studies have demonstrated the utility of machine learning (ML) methods for genomic prediction (GP) of various plant traits, but a clear rationale for choosing ML over conventionally used, often simpler parametric methods, is still ...
Aalt D.J. van Dijk, Shahid Mansoor, Muhammad Farooq, Dick de Ridder, Harm Nijveen   +4 more
doaj   +1 more source

Enhancement of Recombinant Protein Production in Transgenic Nicotiana benthamiana Plant Cell Suspension Cultures with Co-Cultivation of Agrobacterium Containing Silencing Suppressors. [PDF]

, 2018
We have previously demonstrated that the inducible plant viral vector (CMViva) in transgenic plant cell cultures can significantly improve the productivity of extracellular functional recombinant human alpha-1-antiryspin (rAAT) compared with either a ...
Dandekar, Abhaya M, Falk, Bryce W, Huang, Ting-Kuo, McDonald, Karen A   +3 more
core   +3 more sources