Results 1 to 10 of about 6,519,783 (149)

Prior Biological Knowledge Improves Genomic Prediction of Growth-Related Traits in Arabidopsis thaliana

Frontiers in Genetics, 2021
Prediction of growth-related complex traits is highly important for crop breeding. Photosynthesis efficiency and biomass are direct indicators of overall plant performance and therefore even minor improvements in these traits can result in significant ...
Muhammad Farooq, Muhammad Farooq, Aalt D. J. van Dijk, Aalt D. J. van Dijk, Harm Nijveen, Mark G. M. Aarts, Willem Kruijer, Thu-Phuong Nguyen, Shahid Mansoor, Dick de Ridder   +9 more
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Comprehensive Mechanism of Gene Silencing and Its Role in Plant Growth and Development

Frontiers in Plant Science, 2021
Gene silencing is a negative feedback mechanism that regulates gene expression to define cell fate and also regulates metabolism and gene expression throughout the life of an organism.
Ahmed H. El-Sappah, Ahmed H. El-Sappah, Ahmed H. El-Sappah, Kuan Yan, Kuan Yan, Qiulan Huang, Qiulan Huang, Qiulan Huang, Md. Monirul Islam, Quanzi Li, Quanzi Li, Yu Wang, Yu Wang, Muhammad Sarwar Khan, Xianming Zhao, Xianming Zhao, Reyazul Rouf Mir, Jia Li, Jia Li, Khaled A. El-Tarabily, Khaled A. El-Tarabily, Manzar Abbas, Manzar Abbas   +22 more
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Global Analysis of RNA-Dependent RNA Polymerase-Dependent Small RNAs Reveals New Substrates and Functions for These Proteins and SGS3 in Arabidopsis

Non-Coding RNA, 2021
RNA silencing pathways control eukaryotic gene expression transcriptionally or posttranscriptionally in a sequence-specific manner. In RNA silencing, the production of double-stranded RNA (dsRNA) gives rise to various classes of 20–24 nucleotide (nt ...
Xia Hua, Nathan D. Berkowitz, Matthew R. Willmann, Xiang Yu, Eric Lyons, Brian D. Gregory   +5 more
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Dynamic spreading of chromatin-mediated gene silencing and reactivation between neighboring genes in single cells

eLife, 2022
In mammalian cells genes that are in close proximity can be transcriptionally coupled: silencing or activating one gene can affect its neighbors. Understanding these dynamics is important for natural processes, such as heterochromatin spreading during ...
Sarah Lensch, Michael H Herschl, Connor H Ludwig, Joydeb Sinha, Michaela M Hinks, Adi Mukund, Taihei Fujimori, Lacramioara Bintu   +7 more
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Pygmy MicroRNA: Surveillance Cops in Therapy Kingdom

Molecular Medicine, 2016
MicroRNAs (miRNAs) are well preserved in every animal. These pygmy-sized (21–23 nt) noncoding RNAs scattered in the genome are responsible for micromanaging versatile gene regulation.
Utpal Bhadra, Pradipta Patra, Jagamohan Chhatai, Manika Pal-Bhadra   +3 more
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Functional Genomic Screening Reveals Splicing of the EWS-FLI1 Fusion Transcript as a Vulnerability in Ewing Sarcoma

Cell Reports, 2016
Ewing sarcoma cells depend on the EWS-FLI1 fusion transcription factor for cell survival. Using an assay of EWS-FLI1 activity and genome-wide RNAi screening, we have identified proteins required for the processing of the EWS-FLI1 pre-mRNA.
Patrick J. Grohar, Suntae Kim, Guillermo O. Rangel Rivera, Nirmalya Sen, Sara Haddock, Matt L. Harlow, Nichole K. Maloney, Jack Zhu, Maura O’Neill, Tamara L. Jones, Konrad Huppi, Magdalena Grandin, Kristen Gehlhaus, Carleen A. Klumpp-Thomas, Eugen Buehler, Lee J. Helman, Scott E. Martin, Natasha J. Caplen   +17 more
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Identification and Characterization of miRNA Transcriptome in Asiatic Cotton (Gossypium arboreum) Using High Throughput Sequencing

Frontiers in Plant Science, 2017
MicroRNAs (miRNAs) are small 20–24nt molecules that have been well studied over the past decade due to their important regulatory roles in different cellular processes.
Muhammad Farooq, Shahid Mansoor, Shahid Mansoor, Hui Guo, Imran Amin, Peng W. Chee, M. Kamran Azim, Andrew H. Paterson   +7 more
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Secondary siRNAs in Plants: Biosynthesis, Various Functions, and Applications in Virology

Frontiers in Plant Science, 2021
The major components of RNA silencing include both transitive and systemic small RNAs, which are technically called secondary sRNAs. Double-stranded RNAs trigger systemic silencing pathways to negatively regulate gene expression.
Neeti Sanan-Mishra, A. Abdul Kader Jailani, A. Abdul Kader Jailani, Bikash Mandal, Sunil K. Mukherjee   +4 more
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Potato spindle tuber viroid as Inducer of RNA Silencing in Infected Tomato

Molecular Plant-Microbe Interactions, 2001
Potato spindle tuber viroid (PSTVd), an RNA plant pathogen encoding no known proteins, induces systemic symptoms on tomato plants. We report detection of small RNAs of approximately 25 nucleotides with sequence specificity to PSTVd in infected plants: an
Asuka Itaya, Alexey Folimonov, Yoshie Matsuda, Richard S. Nelson, Biao Ding   +4 more
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A Complex Network of MicroRNAs Expressed in Brain and Genes Associated with Amyotrophic Lateral Sclerosis

International Journal of Genomics, 2013
Amyotrophic Lateral Sclerosis (ALS) is a rare neurological disease affecting mainly motor neurons and often leads to paralysis and death in extreme cases.
Santosh Shinde, Neelima Arora, Utpal Bhadra   +2 more
doaj   +1 more source