Results 251 to 260 of about 520,866 (339)

Sequence Analysis of MHC Class II Genes in Cetaceans

, 2012
Yang, Wei-Cheng, Chou, Lien-Siang, Hu, Jer-Ming   +2 more
openaire   +3 more sources

Exploring the Role of T‐Cell Metabolism in Modulating Immunotherapy Efficacy for Non‐Small Cell Lung Cancer Based on Clustering

Journal of Clinical Laboratory Analysis, EarlyView.
We conducted a comprehensive investigation of the metabolic profiles of infiltrating T cells in NSCLC tumors and found metabolic heterogeneity in three T‐cell subtypes, which are associated with the prognosis of ICB therapy. We defined these metabolic clusters as response‐dependent (R) clusters and non‐response‐dependent (NR) clusters, and elucidated ...
Hongzhe Guo, Liangyu Zhang, Hu Tang, Peiwen Liu, Bin Hu, Yue Gong, Rui Hou, Ziheng Wu   +7 more
wiley   +1 more source

Unraveling the architecture of major histocompatibility complex class II haplotypes in rhesus macaques. [PDF]

Genome Res
de Groot N, van der Wiel M, Le NG, de Groot NG, Bruijnesteijn J, Bontrop RE.   +5 more
europepmc   +1 more source

MHC Class II‐Deficient Combined Immunodeficiency: A Disease of Gene Regulation

Immunological Reviews, 1994
Mach, Bernard, Steimle, Viktor, Reith, Walter   +2 more
openaire   +4 more sources

Applying the National Genomic DNA Reference Materials to Evaluate the Performance of Nanopore Sequencing in Identifying Thalassemia Variants

Journal of Clinical Laboratory Analysis, EarlyView.
This study mainly to evaluate the performance of nanopore technology in thalassemia detection by utilizing the national genomic reference materials in China. We proved that the reference materials can be used to evaluate the performance of nanopore sequencing in identifying thalassemia mutations, and it's necessary to incorporate triplicates when ...
Xingyu Wei, Xu Yang, Wanqing Han, Li Zhang, Guojun Ouyang, Shoufang Qu, Fang Yang, Xuexi Yang   +7 more
wiley   +1 more source

An epigenetic pathway regulates MHC-II expression and function in B cell lymphoma models. [PDF]

J Clin Invest
Zhang T, Beytullahoglu O, Tulaiha R, Luvisotto A, Szczepanski A, Tsuboyama N, Zhao Z, Wang L.   +7 more
europepmc   +1 more source

Macrophage and Preeclampsia: Macrophage Polarization Imbalance at the Maternal‐Fetal Interface

Journal of Clinical Laboratory Analysis, EarlyView.
The development and progression of preeclampsia (PE) are associated with immune‐inflammatory responses induced by placental dysfunction. The polarization imbalance of decidual macrophages, particularly the increase in M1 polarization, exacerbates placental inflammation.
Yao Wei, Yang Su, Cheng Liu, Xiaolong Ma, Zihui Ling, Yilin Wang, Rui Qiao   +6 more
wiley   +1 more source

CXCL16 knockout inhibit asthma airway inflammation by suppressing H2-DM molecular mediated antigen presentation. [PDF]

Cell Death Discov
Liu TT, Zhang Z, Deng J, Shi CY, Zheng S, Jia LX, Du J, Piao C.   +7 more
europepmc   +1 more source

Carbon‐ion irradiation together with autophagy inhibition and immune checkpoint inhibitors protect against pancreatic cancer development in mouse model

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
Abstract Background Pancreatic cancer remains fatal because of resistance to chemo‐, radio‐, and immunotherapies. Carbon‐ion radiotherapy (CIRT) has been beneficial for patients with pancreatic cancer. The purpose of this study was to identify the mechanism by which CIRT exerts its anticancer activity, particularly in combination with immunotherapy ...
Makoto Sudo, Yaoyao Wang, Jingren Wang, Koubun Yasuda, Keiko Mitani, Shuhei Hayashi, Masaki Ohmuraya, Hiroko Tsutsui, Jiro Fujimoto   +8 more
wiley   +1 more source

Shared Genetics in Celiac Disease and Inflammatory Bowel Disease Specify a Greater Role for Intestinal Epithelial Cells. [PDF]

Int J Mol Sci
Ribeiro NV, Anwar S, Withoff S, Jonkers IH.   +3 more
europepmc   +1 more source