Results 101 to 110 of about 26,095 (198)
Viral factors in non-progression
Frontiers in Immunology, 2013 Research has undergone considerable development in understanding a small subset of human immunodeficiency virus type 1 (HIV-1)-infected, therapy-naive individuals who maintain a favourable course of infection surviving for longer periods of time ...Bin eWangdoaj +1 more sourceThe Concise Guide to PHARMACOLOGY 2025/26: G protein‐coupled receptors
British Journal of Pharmacology, Volume 182, Issue S1, Page S24-S151, December 2025.The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,Stephen P. H. Alexander, Anthony P. Davenport, Eamonn Kelly, Alasdair J. Gibb, Alistair A. Mathie, Chloe J. Peach, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Christopher Southan, Jamie A. Davies, Maria Pia Abbracchio, George R. Abraham, Alexander Agoulnik, Wayne Alexander, Khaled Al‐hosaini, Magnus Bäck, Jillian G. Baker, Nicholas M. Barnes, Ross Bathgate, Jean‐Martin Beaulieu, Annette G. Beck‐Sickinger, Maik Behrens, Kirstie A. Bennett, Kenneth E. Bernstein, Bernhard Bettler, Nigel J. M. Birdsall, Victoria A. Blaho, Pascal Bonaventure, Francois Boulay, Corinne Bousquet, Hans Bräuner‐Osborne, Andrew J. Brown, Geoffrey Burnstock, Marta Busnelli, Girolamo Caló, Vanni Caruso, Justo P. Castaño, Kevin J. Catt, Stefania Ceruti, Paul Chazot, Nan Chiang, Bice Chini, Arthur Christopoulos, Jerold Chun, Antonia Cianciulli, Olivier Civelli, Lucie H. Clapp, Réjean Couture, Helen M. Cox, Zsolt Csaba, Claes Dahlgren, Frank M. Dautzenberg, Gordon Dent, Steven D. Douglas, Pascal Dournaud, Margarita L. Dubocovich, Satoru Eguchi, Emanuel Escher, Edward J. Filardo, Tung Fong, Huamei Fu Forsman, Marta Fumagalli, Raul R. Gainetdinov, Michael L. Garelja, Marc de Gasparo, Florence Gbahou, Craig Gerard, Marvin Gershengorn, Michelle Glass, David E. Gloriam, Fernand Gobeil, Theodore L. Goodfriend, Cyril Goudet, Lukas Grätz, Karen J. Gregory, Christian Gruber, Andrew L. Gundlach, Jörg Hamann, Julien Hanson, Deborah S. Hartman, Richard L. Hauger, Debbie L. Hay, Akos Heinemann, Laura Heitman, Deron R. Herr, Morley D. Hollenberg, Nicholas D. Holliday, Birgitte Holst, Mastgugu Horiuchi, Daniel Hoyer, László Hunyady, Ahsan Husain, Adriaan P. IJzerman, Tadashi Inagami, Paul A. Insel, Kenneth A. Jacobson, Laura H. Jacobson, Robert T. Jensen, Ralf Jockers, Deepa Jonnalagadda, Sadashiva Karnik, Klemens Kaupmann, Jacqueline Kemp, Charles Kennedy, Yasuyuki Kihara, Julia Kinsolving, Takio Kitazawa, Pawel Kozielewicz, Hans‐Jürgen Kreienkamp, Jyrki P. Kukkonen, Luxmichan Laishram, Tobias Langenhan, Christopher J. Langmead, Dan Larhammar, Katie Leach, Davide Lecca, John D. Lee, Susan E. Leeman, Jérôme Leprince, Rob Leurs, Xaria X. Li, Ines Liebscher, Stephen J. Lolait, Amelie Lupp, Robyn Macrae, Janet J. Maguire, Davide Malfacini, Maurice Manning, Davide Marangon, Kirill Martemyanov, Jean Mazella, Craig A. McArdle, Shlomo Melmed, Martin C. Michel, Laurence J. Miller, Vincenzo Mitolo, Bernard Mouillac, Christa E. Müller, Philip M. Murphy, Jean‐Louis Nahon, Richard R. Neubig, Tony Ngo, Xavier Norel, Duuamene Nyimanu, Anne‐Marie O’Carroll, Stefan Offermanns, Maria Antonietta Panaro, Marc Parmentier, Nicole Perry‐Hauser, Roger G. Pertwee, Jean‐Philippe Pin, Eric R. Prossnitz, Helena Chengxue Qin, Mark Quinn, Stefano Raffaele, Rithwik Ramachandran, Manisha Ray, Rainer K. Reinscheid, Alejandro Romeral Buzón, Philippe Rondard, Mette M. Rosenkilde, G. Enrico Rovati, Chiara Ruzza, Gareth J. Sanger, Nicole Scholz, Torsten Schöneberg, Gunnar Schulte, Stefan Schulz, Deborah L. Segaloff, Charles N. Serhan, Arun K. Shukla, Khuraijam Dhanachandra Singh, Craig M. Smith, Nicola J. Smith, Claudia Stäubert, Leigh A. Stoddart, Yukihiko Sugimoto, Roger Summers, Valerie P. Tan, David M. Thal, Walter ( Wally) Thomas, Pieter B. M. W. M. Timmermans, Kalyan Tirupula, Lawrence Toll, Giovanni Tulipano, Hamiyet Unal, Thomas Unger, Celine Valant, Patrick Vanderheyden, David Vaudry, Hubert Vaudry, Joseph G. Verbalis, Jean‐Pierre Vilardaga, Christopher S. Walker, Ji Ming Wang, Donald T. Ward, Hans‐Jürgen Wester, Gary B. Willars, Tom Lloyd Williams, Trent M. Woodruff, Huixian Wu, Cheng Yang, Chengcan Yao, Richard D. Ye, Nathan Zaidman +206 morewiley +1 more sourceVariation in Quantitative Resistance Components to the Fungus Pseudocercospora fijiensis Causing Black Leaf Streak Disease Among Banana Genotypes
Plant Pathology, Volume 74, Issue 9, Page 2857-2879, December 2025.We assessed the quantitative resistance components of different banana genotypes to the fungus Pseudocercospora fijiensis causing black leaf streak disease in field and controlled conditions. ABSTRACT
Combining different components of quantitative resistance in new banana hybrids has potential for developing efficient and durable control of black leaf ...Cassandre Jolivet, Catherine Abadie, Marcel Bohrer, Sébastien Ravel, Joffrey Mejias, Marine Seidel, Jean‐Claude Efile, Véronique Roussel, Christine Pages, Nadia Lubin, Natalia Saveljeva, Line Baril, Jean Carlier, Frédéric Salmon +13 morewiley +1 more sourceCross-Species Transmission and Evolution of SIV Chimpanzee Progenitor Viruses Toward HIV-1 in Humanized Mice
Frontiers in Microbiology, 2020 The genetic evolution of HIV-1 from its progenitor virus SIV following cross-species transmission is not well understood. Here we simulated the SIVcpz initial transmission to humans using humanized mice and followed the viral evolution during serial ...Kimberly Schmitt, James Curlin, Leila Remling-Mulder, Ryan Moriarty, Kelly Goff, Shelby O’Connor, Mark Stenglein, Preston Marx, Preston Marx, Ramesh Akkina +9 moredoaj +1 more sourceImpact of Human Immunodeficiency Virus in the Pathogenesis and Outcome of Patients with Glioblastoma Multiforme. [PDF]
, 2016 BackgroundImprovement in antiviral therapies have been accompanied by an increased frequency of non-Acquired Immune Deficiency Syndrome (AIDS) defining malignancies, such as glioblastoma multiforme.Bui, Timothy T, Choy, Winward, Lagman, Carlito, Lee, Seung J, Safaee, Michael, Yang, Isaac +5 morecore +1 more sourceIdentification of potential HIV restriction factors by combining evolutionary genomic signatures with functional analyses. [PDF]
, 2015 BACKGROUND: Known antiretroviral restriction factors are encoded by genes that are under positive selection pressure, induced during HIV-1 infection, up-regulated by interferons, and/or interact with viral proteins.Ciuffi, A., Gawanbacht, A., Götz, N., Heilmann, J., Hotter, D., Kirchhoff, F., Kluge, S.F., Krapp, C., Mack, K., McLaren, P.J., Munoz, M., Perreaud, J., Pyndiah, N., Rausell, A., Sauter, D., Telenti, A., Thompson, D. +16 morecore +2 more sourcesMetabolic Reprogramming in Lung Cancer: Hallmarks, Mechanisms, and Targeted Strategies to Overcome Immune Resistance
Cancer Medicine, Volume 14, Issue 21, November 2025.ABSTRACT Background
Lung cancer remains the leading cause of cancer‐related mortality worldwide. Although immunotherapy has revolutionized lung cancer treatment, its efficacy is often hindered by primary and acquired immune resistance. Increasing evidence indicates that metabolic reprogramming plays a crucial role in tumor progression and the ...Yi Chen, Menglin Bai, Ming Liu, Zhenshan Zhang, Chenxue Jiang, Kejin Li, Yun Chen, Yaping Xu, Leilei Wu +8 morewiley +1 more sourceNatural variation of the nef gene in human immunodeficiency virus type 2 infections in Portugal
Journal of General Virology, 2003 Human immunodeficiency virus type 2 (HIV-2) infections cause severe immunodeficiency in humans, although HIV-2 is associated frequently with reduced virulence and pathogenicity compared to HIV-1. Genetic determinants that play a role in HIV pathogenesis are relatively poorly understood but nef has been implicated in inducing a more pathogenic phenotype Elizabeth, Padua, Adrian, Jenkins, Stuart, Brown, Janet, Bootman, Maria Teresa, Paixao, Neil, Almond, Neil, Berry +6 moreopenaire +2 more sourcesHIF‐1 Targeting Intervention Renders Protection From Alzheimer's‐Like Pathology in a Humanized Mice Model of HIV Infection
Journal of Extracellular Vesicles, Volume 14, Issue 11, November 2025.This study explored the use of astrocyte‐derived extracellular vesicles (ADEVs) to deliver siRNA targeting HIF‐1α in HIV‐infected humanized mice, aiming to combat HIV‐associated Alzheimer's‐like pathology and associated synaptodegeneration. Intranasal delivery of these vesicles effectively reached key brain areas, reduced HIF‐1α expression, protected ...Sudipta Ray, Mohit Kumar, Divya T. Chemparathy, Prasanta K. Dash, Susmita Sil +4 morewiley +1 more source
