Results 131 to 140 of about 12,393 (180)

Nef Genes of SIV

Journal of Medical Primatology, 1990
Molecular clones of SIVmac were constructed that differed only in sequences within the nef gene. DEAE‐transfection of viral DNA containing an open form of /ic/yiclded virus that replicated with similar kinetics and to a similar extent in macaque peripheral blood lymphocyte (PBL) cultures as virus with a deletion or stop codon within nef. Rhesus monkeys
H W, Kestler   +6 more
openaire   +2 more sources

Specificity of anti-Nef antibodies produced in mice immunized with DNA encoding the HIV-1 nef gene product

Vaccine, 1999
Mice immunized with plasmid DNA encoding Nef regulatory protein of human immunodeficiency virus type 1 developed high levels of anti-Nef antibodies. After 4 intramuscular injections of 100 microg plasmid DNA, anti-Nef antibodies reached titers up to 2 x 10(4). A significant specific antibody response was maintained for at least 16 months.
C, Moureau   +4 more
openaire   +2 more sources

Serological detection of attenuated HIV-1 variants with nef gene deletions

AIDS, 1998
To investigate whether members of a transfusion-linked cohort (the Sydney Bloodbank Cohort) infected with a nef-deleted strain of HIV-1 could be differentiated from individuals infected with wild-type strains of HIV-1 by characterizing the Nef antibody response of cohort members.Retrospective and prospective analysis of the nef gene sequence and the ...
A L, Greenway   +4 more
openaire   +2 more sources

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