Results 131 to 140 of about 13,075 (222)

Critical role for Nef in HIV-1–induced podocyte dedifferentiation

, 2003
Critical role for Nef in HIV-1–induced podocyte dedifferentiation. The notable glomerular feature of human immunodeficiency virus (HIV)-associated nephropathy (HIVAN) is the collapse of the capillary tuft with marked glomerular epithelial cell ...
He, John Cijiang, SCHWARTZ, Elissa J, Husain, Mohammad, KLOTMAN, Paul E, Schwartz, Elissa J., Klotman, Paul E., Sunamoto, Masaaki   +6 more
core   +1 more source

Marked epitope- and allele-specific differences in rates of mutation in human immunodeficiency type 1 (HIV-1) Gag, Pol, and Nef cytotoxic T-lymphocyte epitopes in acute/early HIV-1 infection

, 2008
During acute human immunodeficiency virus type 1 (HIV-1) infection, early host cellular immune responses drive viral evolution. The rates and extent of these mutations, however, remain incompletely characterized.
Carrington, M., Brumme, Z. L., John, M., Altfeld, M., Streeck, H., Markowitz, M., Block, B. L., Kaldor, J., Heckerman, D., Kelleher, A. D., Carlson, J., Jessen, H., Kadie, C., Yuki, Y., Rosenberg, E., Walker, B. D., Eichbaum, Q., Baker, B., Allen, T. M., Brumme, C. J., Mallal, S.   +20 more
core  

[Primers for the nef gene in the diagnosis of HIV infection using the polymerase chain reaction].

Voprosy virusologii, 1994
A new system of primers and internal probe identifying the nef gene of HIV-1 was selected and tested for the laboratory diagnosis of HIV infection by means of PCR. The proposed primers and probe by their characteristics approached the optimal ones for PCR diagnosis.
S N, Radiuk, G R, Matsevich, V Z, Tarantul, O G, Andzhaparidze   +3 more
openaire   +1 more source

Replication-competent SIVcpz CRISPR screen identifies barriers to successful cross-species transmission. [PDF]

J Virol
Xie Q, Wang Q, Noettger S, Gosálbez G, Betzler AC, Volcic M, Kmiec D, Krebs S, Graf A, Gülensoy D, Weidinger G, Sparrer KMJ, Kirchhoff F.   +12 more
europepmc   +2 more sources

Stable expression of HIV-1 Nef induces changes in growth properties and activation state of human astrocytes

, 1999
OBJECTIVE: Nef was shown to be the predominant viral protein expressed in HIV-1-infected astrocytes in vivo and in vitro suggesting a distinct role of Nef in this cell type.
Kohleisen, B., Shumay, E., Nuesse, M., Foerster, R., Sutter, G., Erfle, V., Brack-Werner, R.   +6 more
core  

HIV Nef-mediated WAVE2-ARP2/3 inhibition underlies CD4⁺ T-cell lamellipodial abnormalities and immune dysfunction. [PDF]

mBio
Dunn DC, Crater JM, Del Río Estrada PM, Malgady JM, Haas G, Klain W, Torres-Ruiz MF, Luna-Villalobos YA, González-Navarro M, Kang C, Kovacs C, Ávila-Ríos S, Lee B, Jolicoeur P, Nixon DF, Furler O'Brien RL.   +15 more
europepmc   +1 more source

In-vivo use of SIVmac239 with a reversing stop codon in the SIV nef gene

AIDS, 2020
openaire   +3 more sources

Biomimetic bone scaffold functionalized with traditional Chinese medicine ingredients and collagen-binding IGF-1 for bone regeneration. [PDF]

J Mater Sci Mater Med
Gao X, Lei B, Zhao X, Zhang Y.
europepmc   +1 more source

Molecular Mechanisms Underlying the Anti-Tumor Activity of Lotus-Derived Alkaloids in Breast Cancer. [PDF]

Molecules
He Q, Luo L, Zhang D, Zhou W, Bai N, Du C, Li S.   +6 more
europepmc   +1 more source

HIV and Cancer: Insights into Viral-Mediated Oncogenesis and Immunosuppression. [PDF]

Pathogens
Lasagna A, Pozza G, Matone M, Fasola C, Ruggieri L, La Verde N, Pedrazzoli P, Dalu D.   +7 more
europepmc   +1 more source