Results 41 to 50 of about 1,695,057 (181)
, 2023 1899 gründete Karl Nef die Ortsgruppe Basel der Internationalen Gesellschaft für Musik. Nach der einseitigen Auflösung der I.G.M. durch den deutschen Landesverein, wurde die Ortsgruppe Basel zum einem Rückzugsort für die Vernetzung von ...
Urchueguía, Cristina
core +1 more source
Journal of Neuroinflammation, 2018 Background HIV-associated neurocognitive disorder (HAND) is a neurodegenerative disease associated with persistent neuroinflammation and subsequent neuron damage.
Feng Zhou +16 more
doaj +1 more source
Pathogens, 2022 HIV-1 infection of myeloid cells is associated with the induction of an IFN response. How HIV-1 manipulates and subverts the IFN response is of key interest for the design of therapeutics to improve immune function and mitigate immune dysregulation in ...
Laura J. Martins +5 more
doaj +1 more source
The R203W substitution drives PACS‐1 syndrome by disrupting intramolecular regulation
The FEBS Journal, EarlyView.The middle region (MR) of PACS‐1 controls engagement with specific partner proteins. This manuscript presents the structure of the Furin binding region (FBR) and how interactions with partners are regulated through the interplay between a basic patch in the FBR and an acidic cluster in the MR.
Troy C. Krzysiak +7 more
wiley +1 more source
Safety and immunogenicity of DNA and MVA HIV-1 subtype C vaccine prime-boost regimens: a phase I randomised Trial in HIV-uninfected Indian volunteers. [PDF]
PLoS ONE, 2013 STUDY DESIGN: A randomized, double-blind, placebo controlled phase I trial. METHODS: The trial was conducted in 32 HIV-uninfected healthy volunteers to assess the safety and immunogenicity of prime-boost vaccination regimens with either 2 doses of ADVAX,
Sanjay Mehendale +20 more
doaj +1 more source
Contribution of endosomal proteins EHD1 and EHD4 to the HIV‐1 replication cycle
The FEBS Journal, EarlyView.EHD1 and EHD4, two key trafficking proteins, regulate multiple stages of HIV‐1 infection: In producer cells, they help produce fully infectious virus particles, regulate Envelope protein incorporation in a cell‐type‐dependent manner, and limit the accumulation of antiviral IFITM proteins in virions.
Grégory Pacini +4 more
wiley +1 more source
The Vpr protein from HIV-1: distinct roles along the viral life cycle
Retrovirology, 2005 The genomes of human and simian immunodeficiency viruses (HIV and SIV) encode the gag, pol and env genes and contain at least six supplementary open reading frames termed tat, rev, nef, vif, vpr, vpx and vpu. While the tat and rev genes encode regulatory
Benichou Serge, Le Rouzic Erwann
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Viruses, 2021 We aimed to investigate whether the sequence length of HIV-1 increases over time. We performed a longitudinal analysis of full-length coding region sequences (FLs) during an HIV-1 outbreak among patients with hemophilia and local controls infected with ...
Young-Keol Cho +2 more
doaj +1 more source
Insect Conservation and Diversity, EarlyView.Integrative DNA barcoding of ambrosia beetles and host plants revealed 27 beetle species across 16 genera and extensive, previously undocumented host plant diversity in Laos and Vietnam. Host specificity varied widely among ambrosia beetles, with Xylosandrus crassiusculus emerging as a dominant generalist associated with 19 host species from 12 plant ...
Bounsanong Chouangthavy +10 more
wiley +1 more source
Nef induced transcriptional alteration of the six genes measured by qPCR.
, 2015 Real Time RT-PCR was performed to analyse the expression of the six genes. Fold change in expression upon Nef transfection is presented in respect to control. Except VDAC1 all 5 genes were downregulated by Nef variants.
Sudipti Gupta (721839) +5 more
core +1 more source