Results 51 to 60 of about 1,695,057 (181)

Unmasking the Influence of Viral Micro‐RNAs on Host Immunity

Immunology &Cell Biology, EarlyView.
Viral micro‐RNAs are increasingly recognized as key modulators of host–virus interactions. They influence multiple immune functions, including antigen presentation, T‐cell activation, and cytokine signaling, while also tuning viral gene expression to promote persistence.
Riley J. K. Easton, Bernadette M. Saunders   +1 more
wiley   +1 more source

Isabelle Nef, Harpischordist and the University Sinfonietta, December 28, 1963 [PDF]

, 1963
Concert program for Isabelle Nef, Harpischordist and the University Sinfonietta, December 28 ...

core  

Vaccine-induced immune responses against both Gag and Env improve control of simian immunodeficiency virus replication in rectally challenged rhesus macaques.

PLoS Pathogens, 2017
The ability to control lentivirus replication may be determined, in part, by the extent to which individual viral proteins are targeted by the immune system.
Mauricio A Martins, Young C Shin, Lucas Gonzalez-Nieto, Aline Domingues, Martin J Gutman, Helen S Maxwell, Iris Castro, Diogo M Magnani, Michael Ricciardi, Nuria Pedreño-Lopez, Varian Bailey, Dillon Betancourt, John D Altman, Matthias Pauthner, Dennis R Burton, Benjamin von Bredow, David T Evans, Maoli Yuan, Christopher L Parks, Keisuke Ejima, David B Allison, Eva Rakasz, Glen N Barber, Saverio Capuano, Jeffrey D Lifson, Ronald C Desrosiers, David I Watkins   +26 more
doaj   +1 more source

Molecular Chaperone Networks in Plants: Maintaining Proteostasis and Enhancing Stress Resilience for Crop Improvement

Plant, Cell &Environment, EarlyView.
ABSTRACT Molecular chaperones play a central role in the plant proteostasis machinery by aiding the folding of nascent proteins, preventing aggregation, and repairing or degrading damaged proteins. These functions are especially essential during abiotic and biotic stress, which can destabilise cellular proteins and disrupt metabolic homoeostasis.
Mingfang Yang, Anqin Gao, Tsz‐Yan Chan, Hafiz Mamoon Rehman, Sehar Nawaz, Sehrish Bashir, Noman Mahmood, Muhammad Wajid Ullah, Chunlin Long, Hon‐Ming Lam, Muhammad Arif   +10 more
wiley   +1 more source

The Chaetocerosphere: Chaetoceros Species and Associated Prokaryotes in a Coastal Area

Environmental Microbiology Reports, Volume 18, Issue 5, October 2026.
Chaetoceros species maintain recurrent distinct prokaryotic assemblages in their phycosphere. Alphaproteobacteria, Bacteroidetes and Archaea Thermoplasmata and Marine Group II are the most represented in the phycosphere. Bipartite networks highlight strong links between the diatom and specific prokaryotic taxa, especially the chain‐forming species ...
Anna Chiara Trano, Raffaella Casotti, Roberta Piredda   +2 more
wiley   +1 more source

Impacts of Humanized Mouse Models on the Investigation of HIV-1 Infection: Illuminating the Roles of Viral Accessory Proteins in Vivo

Viruses, 2015
Human immunodeficiency virus type 1 (HIV-1) encodes four accessory genes: vif, vpu, vpr, and nef. Recent investigations using in vitro cell culture systems have shed light on the roles of these HIV-1 accessory proteins, Vif, Vpr, Vpu, and Nef, in ...
Eri Yamada, Rokusuke Yoshikawa, Yusuke Nakano, Naoko Misawa, Yoshio Koyanagi, Kei Sato   +5 more
doaj   +1 more source

Engineering and Validation of a Vector for Concomitant Expression of Rare Transfer RNA (tRNA) and HIV-1 nef Genes in Escherichia coli. [PDF]

PLoS ONE, 2015
Relative ease in handling and manipulation of Escherichia coli strains make them primary candidate to express proteins heterologously. Overexpression of heterologous genes that contain codons infrequently used by E. coli is related with difficulties such
Siti Aisyah Mualif, Sin-Yeang Teow, Tasyriq Che Omar, Yik Wei Chew, Narazah Mohd Yusoff, Syed A Ali   +5 more
doaj   +1 more source

Nonpathogenic SIV Infection in Sooty Mangabeys Is Characterized by a Lack of Activation and Expansion of Monocytes

Journal of Medical Primatology, Volume 55, Issue 5, October 2026.
ABSTRACT Introduction Natural hosts of simian immunodeficiency virus (SIV), including sooty mangabeys (SMs), maintain high viremia without progressing to AIDS and AIDS‐associated histopathogenesis. The mechanisms underlying this protection and lack of pathogenesis remain incompletely understood, particularly in relation to monocyte/macrophage ...
Caroline Soulas, Hai Duc Nguyen, Summer Siddiqui, Natalie Stahr, Tricia H. Burdo, Francis J. Novembre, Woong‐Ki Kim, Kenneth C. Williams   +7 more
wiley   +1 more source

Analysis of human immunodeficiency virus type 1 nef gene sequences present in vivo. [PDF]

, 1993
The nef genes of the human immunodeficiency viruses type 1 and 2 (HIV-1 and HIV-2) and the related simian immunodeficiency viruses (SIVs) encode a protein (Nef) whose role in virus replication and cytopathicity remains uncertain.
Nantermet, Pascale V., Seillier-Moiseiwitsch, Francoise, Glueck, Deborah H., Shugars, Diana C., Smith, Marilyn S., Swanstrom, Ronald   +5 more
core   +1 more source

The role of Nef in the long-term persistence of the replication-competent HIV reservoir in South African women

Journal of Virology
HIV-1 Nef mediates immune evasion and viral pathogenesis in part through the downregulation of cell surface cluster of differentiation 4 (CD4) and major histocompatibility complex class I (MHC-I) on infected cells.
Sherazaan D. Ismail, Shorok Sebaa, Bianca Abrahams, Martha C. Nason, Mitchell J. Mumby, Jimmy D. Dikeakos, Sarah B. Joseph, Matthew Moeser, Ronald Swanstrom, Nigel Garrett, Carolyn Williamson, Thomas C. Quinn, Melissa-Rose Abrahams, Andrew D. Redd   +13 more
doaj   +1 more source