Results 81 to 90 of about 26,095 (198)

Deletion, insertion and stop codon mutations in vif genes of HIV-1 infecting slow progressor patients

Journal of Infection in Developing Countries, 2009
Background: Variable progression towards AIDS has been described and has been related to viral and host factors. Around 10% of the HIV-1 infected patients are slow progressors (SP), not presenting with AIDS disease signs even after more than 10 years of ...
Héctor Rafael Rangel, Domingo Garzaro, Anny Karely Rodríguez, Alvaro Hernán Ramírez, Gladys Ameli, Cristina del Rosario Gutiérrez, Flor Helene Pujol   +6 more
doaj   +1 more source

Selection, transmission, and reversion of an antigen-processing cytotoxic T-lymphocyte escape mutation in Human Immunodeficiency Virus Type 1 infection [PDF]

, 2004
Numerous studies now support that human immunodeficiency virus type 1 (HIV-1) evolution is influenced by immune selection pressure, with population studies showing an association between specific HLA alleles and mutations within defined cytotoxic T ...
Allen, T.M., Altfeld, M., Brander, C., Cohen, D.E., Freedberg, K.A., Goulder, P.J.R., John, M., Johnston, M.N., Kalife, E.T., Le Gall, S., Lee, P.K., Lichterfeld, M., Mallal, S.A., Mothe, B.R., O'Sullivan, K.M., Rosenberg, E.S., Sette, A., Strick, D.A., Walker, B.D., Yu, X.G.   +19 more
core   +2 more sources

Matching Multiple Backgrounds: Egg Camouflage Across Different Habitats in a Shorebird

Ecology and Evolution, Volume 16, Issue 1, January 2026.
We studied egg camouflage in Kentish plovers nesting in two visually distinct habitats, sandy beaches and salt marshes, in southern Spain. Despite initial expectations of local adaptation or compromise camouflage, the birds instead chose nest sites within each habitat that shared overlapping colour and visual texture characteristics, allowing effective
Alexandra Grandón‐Ojeda, Tamás Székely, Robert N. Kelsh, Alejandro Pérez‐Hurtado, Innes C. Cuthill   +4 more
wiley   +1 more source

Inhibition of Protein Synthesis by the Human Immunodeficiency Virus Type 1 nef Gene Product

Journal of General Virology, 1994
During productive infection of human T lymphocytes in cell culture, the expression of human immunodeficiency virus type 1 is temporally regulated by virus-encoded regulatory proteins. Among these Nef, whose function has not been clearly elucidated, is thought to alter CD4+ T cells.
L, Poulin, M, Fauchon, A, Darveau, J A, Levy   +3 more
openaire   +2 more sources

Primate lentiviruses use at least three alternative strategies to suppress NF-κB-mediated immune activation.

PLoS Pathogens, 2017
Primate lentiviruses have evolved sophisticated strategies to suppress the immune response of their host species. For example, HIV-2 and most simian immunodeficiency viruses (SIVs) use their accessory protein Nef to prevent T cell activation and ...
Dominik Hotter, Teresa Krabbe, Elisabeth Reith, Ali Gawanbacht, Nadia Rahm, Ahidjo Ayouba, Benoît Van Driessche, Carine Van Lint, Martine Peeters, Frank Kirchhoff, Daniel Sauter   +10 more
doaj   +1 more source

Role of androgen and gonadotrophins in the development and function of the Sertoli cells and Leydig cells: data from mutant and genetically modified mice [PDF]

, 2009
Development and maintenance of the male phenotype and establishment of fertility are all dependent upon the activity of the Sertoli cells and Leydig cells of the testis.
Abel, M.H., Baker, P.J., Huhtaniemi, I., Morris, I.D., O'Shaughnessy, P.J.   +4 more
core   +1 more source

Acute Heat Priming Dampens Gene Expression Response to Thermal Stress in a Widespread Acropora Coral

Ecology and Evolution, Volume 16, Issue 1, January 2026.
(a) Experimental design. Corals from 10 genotypes were distributed across two experimental blocks, each containing nine flow‐through tanks. Fragments from five genotypes were placed in each tank. (b) Temperature profiles and sampling time points in the heat stress assay, demonstrating ramp up from control conditions (27ºC, MMM) to the preconditioning ...
Declan J. A. Stick, W. Jason Kennington, Carolina Castro‐Sanguino, Shannon L. Duffy, James P. Gilmour, Luke Thomas   +5 more
wiley   +1 more source

HLA-Associated viral mutations are common in human immunodeficiency virus type 1 elite controllers [PDF]

, 2009
Elite controllers (EC) of human immunodeficiency virus type 1 (HTV-1) maintain viremia below the limit of detection without antiretroviral treatment. Virus-specific cytotoxic CD8+ T lymphocytes are believed to play a crucial role in viral containment ...
Block, B. L., Brockman, M. A., Brumme, C. J., Brumme, Z. L., Harrigan, P. R., John, M., Mallal, S., Miura, T., Pereyra, F., Trocha, A., Walker, B. D.   +10 more
core   +2 more sources

Trained Immunity and Cardiovascular Risk: An Immunological Perspective

Immunological Reviews, Volume 337, Issue 1, January 2026.
ABSTRACT Systemic inflammation is a key driver of atherogenesis and its complications. While anti‐inflammatory therapies targeting pathways such as IL‐1β and IL‐6 have shown promise in established atherosclerotic cardiovascular disease (ASCVD), potential systemic effects raise concerns about immune suppression and infection, underscoring the need for ...
Katherine A. Boden, Jason Chai, Tafadzwa T. J. Kufazvinei, Robin P. Choudhury   +3 more
wiley   +1 more source

Phylogenetic Analysis of the EarliestnefGene from Hemophiliacs and Local Controls in Korea

BioResearch Open Access, 2012
Twenty hemophiliacs (HPs) were found to have human immunodeficiency virus type-1 (HIV-1) 1-2 years after exposure to Factor IX manufactured in Korea in late 1989. Plasma samples collected from donors O and P during their pre-seroconversion acute infection stage were used to manufacture clotting factors, including Factor IX, to treat these patients.
Cho, Young-Keol, Kim, Jung-Eun, Foley, Brian T.   +2 more
openaire   +2 more sources