Results 1 to 10 of about 1,068,897 (299)
Unveiling hypoxic regulatory networks by bioinformatics: mechanisms of hypoxia-related hub genes driving rituximab resistance and poor prognosis in DLBCL [PDF]
Frontiers in OncologyBackgroundDiffuse large B-cell lymphoma (DLBCL), an aggressive subtype of non-Hodgkin lymphoma, exhibits heterogeneous clinical outcomes. While rituximab, a CD20 inhibitor, combined with chemotherapy has improved survival in some patients, resistance ...
Jiayi Yao +5 more
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Strigolactone-Mediated Trehalose Enhances Salt Resistance in Tomato Seedlings
Horticulturae, 2023 Strigolactones (SLs) are newly discovered plant hormones that modulate a variety of physiological and biochemical processes and plant stress responses.
Xuefang Lu +6 more
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Master regulator genes and their impact on major diseases [PDF]
PeerJ, 2020 Master regulator genes (MRGs) have become a hot topic in recent decades. They not only affect the development of tissue and organ systems but also play a role in other signal pathways by regulating additional MRGs.
Wanwan Cai +7 more
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Novel Roles of SPATULA in the Control of Stomata and Trichome Number, and Anthocyanin Biosynthesis
Plants, 2023 The bHLH transcription factor SPATULA (SPT) has been identified as a regulator during different stages of Arabidopsis development, including the control of leaf size. However, the mechanism via which it performs this function has not been elucidated.
Judith Jazmin Bernal-Gallardo +3 more
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A two-component system (XydS/R) controls the expression of genes encoding CBM6-containing proteins in response to straw in Clostridium cellulolyticum. [PDF]
PLoS ONE, 2013 The composition of the cellulosomes (multi enzymatic complexes involved in the degradation of plant cell wall polysaccharides) produced by Clostridium cellulolyticum differs according to the growth substrate. In particular, the expression of a cluster of
Hamza Celik +8 more
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Nanoplasmonic gene regulation [PDF]
Current Opinion in Chemical Biology, 2010 This review focuses on the recent developments in nanoplasmonic gene regulations. Types of nanoplasmonic carriers and DNA/RNA cargo are described. Strategies to liberate cargo from their carriers using NIR and enable on-demand silencing of endogenous intracellular genes are reviewed.
Somin Eunice, Lee, Luke P, Lee
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Frontiers in Genetics, 2022 Over 170 RNA modifications have been identified after transcriptions, involving in regulation of RNA splicing, processing, translation and decay. Growing evidence has unmasked the crucial role of N6-methyladenosine (m6A) in cancer development and ...
Zhanzhan Li +5 more
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Gene Regulatory Network Inferences Using a Maximum-Relevance and Maximum-Significance Strategy. [PDF]
PLoS ONE, 2016 Recovering gene regulatory networks from expression data is a challenging problem in systems biology that provides valuable information on the regulatory mechanisms of cells.
Wei Liu, Wen Zhu, Bo Liao, Xiangtao Chen
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BMC Musculoskeletal Disorders, 2023 Background Ankylosing spondylitis (AS) is one of the most common immune-mediated arthritic diseases worldwide. Despite considerable efforts to elucidate its pathogenesis, the molecular mechanisms underlying AS are still not fully understood.
Han Wang +6 more
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iScience, 2022 Summary: Recent evidence demonstrates that colon cancer stem cells (CSCs) can generate neurons that synapse with tumor innervating fibers required for tumorigenesis and disease progression. Greater understanding of the mechanisms that regulate CSC driven
Joseph L. Regan +15 more
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