Results 21 to 30 of about 2,134,276 (240)

The retinoblastoma protein modulates Tbx2 functional specificity [PDF]

, 2010
Tbx2 is a member of a large family of transcription factors defined by homology to the T-box DNA-binding domain. Tbx2 plays a key role in embryonic development, and in cancer through its capacity to suppress senescence and promote invasiveness.
Colin R. Goding, Heather M. Shaw, Sascha Ott, Keith W. Vance, Mercedes Rodriguez, Rodriguez, Mercedes, Goding, Colin R., Ott, Sascha, Shaw, Heather M., Vance, Keith W.   +9 more
core   +1 more source

Metachronous retinoblastoma and neuroblastoma

Journal of Pediatric Surgery Case Reports, 2020
Retino- and neuroblastoma are primitive neuroectodermal tumors which share common histology, and embryological origin. However, no apparent correlation was found that can link them both such as common genes.
Ameer Kakaje, MD, Osama Hosam Aldeen, MD, Yousef Mahmoud, MD, Othman Hamdan, MD, PhD   +3 more
doaj   +1 more source

MDM2 as a Modifier Gene in Retinoblastoma [PDF]

JNCI: Journal of the National Cancer Institute, 2010
Variability in the age of onset and number of tumors is occasionally described among retinoblastoma patients, and possible genetic modifiers might lie in the pRB or p53 pathways, both of which are involved in the development of retinoblastoma. MDM2, which increases p53 and pRB catabolism, is therefore a prominent candidate.
Laurent, Castéra, Audrey, Sabbagh, Catherine, Dehainault, Dorothée, Michaux, Audrey, Mansuet-Lupo, Blandine, Patillon, Estelle, Lamar, Isabelle, Aerts, Livia, Lumbroso-Le Rouic, Jérôme, Couturier, Dominique, Stoppa-Lyonnet, Marion, Gauthier-Villars, Claude, Houdayer   +12 more
openaire   +2 more sources

Guidelines for imaging retinoblastoma: imaging principles and MRI standardization [PDF]

, 2011
Retinoblastoma is the most common intraocular tumor in children. The diagnosis is usually established by the ophthalmologist on the basis of fundoscopy and US.
Sophia Göricke, Rodjan, F., Philippe Maeder, Jonas A. Castelijns, de Graaf, P., Maeder, P., Paolo Galluzzi, Pim de Graaf, Castelijns, J.A., Hervé J. Brisse, Galluzzi, P., null null, Firazia Rodjan, Brisse, H.J., Galluzzi, Paolo, Maeder, Philippe, Brisse, Hervé J., de Graaf, Pim, Göricke, Sophia, Castelijns, Jonas A., Rodjan, Firazia, Göricke, S.   +21 more
core   +1 more source

Identificación de tres nuevas mutaciones en el gen RB1 en pacientes con retinoblastoma esporádico en Colombia

Biomédica: revista del Instituto Nacional de Salud, 2013
Introducción. El retinoblastoma es un cáncer pediátrico de la retina originado por la expresión alterada o ausente de la proteína del retinoblastoma (pRb).
Martha Lucía Serrano, Juan José Yunis
doaj   +1 more source

Repression of germline RNAi pathways in somatic cells by retinoblastoma pathway chromatin complexes. [PDF]

PLoS Genetics, 2012
The retinoblastoma (Rb) tumor suppressor acts with a number of chromatin cofactors in a wide range of species to suppress cell proliferation. The Caenorhabditis elegans retinoblastoma gene and many of these cofactors, called synMuv B genes, were ...
Xiaoyun Wu, Zhen Shi, Mingxue Cui, Min Han, Gary Ruvkun   +4 more
doaj   +1 more source

Retinoblastoma [PDF]

, 1999
Review on Retinoblastoma, with data on clinics, and the genes ...
Lohmann, DR
core   +1 more source

Novel miRNA-31 and miRNA-200a-Mediated Regulation of Retinoblastoma Proliferation. [PDF]

PLoS ONE, 2015
Retinoblastoma is the most common intraocular tumor in children. Current management includes broad-based treatments such as chemotherapy, enucleation, laser therapy, or cryotherapy.
Vanessa Montoya, Hanli Fan, Paul J Bryar, Joanna L Weinstein, Marilyn B Mets, Gang Feng, Joshua Martin, Alissa Martin, Hongmei Jiang, Nikia A Laurie   +9 more
doaj   +1 more source

Genetics in ophthalmology: molecular blueprints of retinoblastoma

Human Genomics, 2023
This review presents current knowledge on the molecular biology of retinoblastoma (RB). Retinoblastoma is an intraocular tumor with hereditary and sporadic forms.
Leon Marković, Anja Bukovac, Ana Maria Varošanec, Nika Šlaus, Nives Pećina-Šlaus   +4 more
doaj   +1 more source

Networks of MicroRNAs and Genes in Retinoblastomas

Asian Pacific Journal of Cancer Prevention, 2013
Through years of effort, researchers have made notable progress in gene and microRNA fields about retinoblastoma morbidity. However, experimentally validated data for genes, microRNAs (miRNAs) and transcription factors (TFs) can only be found in a scattered form, which makes it difficult to conclude the relationship between genes and retinoblastoma ...
Jie, Li, Zhi-Wen, Xu, Kun-Hao, Wang, Ning, Wang, De-Qiang, Li, Shang, Wang   +5 more
openaire   +3 more sources