Results 21 to 30 of about 11,860,410 (381)

tRNAscan-SE: a program for improved detection of transfer RNA genes in genomic sequence.

Nucleic Acids Research, 1997
We describe a program, tRNAscan-SE, which identifies 99-100% of transfer RNA genes in DNA sequence while giving less than one false positive per 15 gigabases.
T. Lowe, S. Eddy
semanticscholar   +1 more source

Identification of acquired antimicrobial resistance genes

Journal of Antimicrobial Chemotherapy, 2012
Objectives Identification of antimicrobial resistance genes is important for understanding the underlying mechanisms and the epidemiology of antimicrobial resistance.
E. Zankari, H. Hasman, Salvatore Cosentino, M. Vestergaard, Simon Rasmussen, O. Lund, F. Aarestrup, M. Larsen   +7 more
semanticscholar   +1 more source

Genes, genes everywhere... [PDF]

Nature Reviews Cancer, 2012
Recently published papers using massively parallel sequencing to look at mutations in breast cancer provide food for thought.
openaire   +3 more sources

Genetic targeting and anatomical registration of neuronal populations in the zebrafish brain with a new set of BAC transgenic tools

Scientific Reports, 2017
Genetic access to small, reproducible sets of neurons is key to an understanding of the functional wiring of the brain. Here we report the generation of a new Gal4- and Cre-driver resource for zebrafish neurobiology.
Dominique Förster, Irene Arnold-Ammer, Eva Laurell, Alison J. Barker, António M. Fernandes, Karin Finger-Baier, Alessandro Filosa, Thomas O. Helmbrecht, Yvonne Kölsch, Enrico Kühn, Estuardo Robles, Krasimir Slanchev, Tod R. Thiele, Herwig Baier, Fumi Kubo   +14 more
doaj   +1 more source

Genotype-Phenotype Correlations of Pathogenic COCH Variants in DFNA9: A HuGE Systematic Review and Audiometric Meta-Analysis

Biomolecules, 2022
Pathogenic missense variants in COCH are associated with DFNA9, an autosomal dominantly inherited type of progressive sensorineural hearing loss with or without vestibular dysfunction.
Sybren M. M. Robijn, Jeroen J. Smits, Kadriye Sezer, Patrick L. M. Huygen, Andy J. Beynon, Erwin van Wijk, Hannie Kremer, Erik de Vrieze, Cornelis P. Lanting, Ronald J. E. Pennings   +9 more
doaj   +1 more source

Normalization of Real-Time Quantitative Reverse Transcription-PCR Data: A Model-Based Variance Estimation Approach to Identify Genes Suited for Normalization, Applied to Bladder and Colon Cancer Data Sets

Cancer Research, 2004
Accurate normalization is an absolute prerequisite for correct measurement of gene expression. For quantitative real-time reverse transcription-PCR (RT-PCR), the most commonly used normalization strategy involves standardization to a single ...
C. Andersen, J. L. Jensen, T. Ørntoft
semanticscholar   +1 more source

Intestine-enriched apolipoprotein b orthologs are required for stem cell progeny differentiation and regeneration in planarians

Nature Communications, 2022
Lipid metabolism regulates stem cell states and differentiation. Here, the authors demonstrate a requirement in planarians for Apolipoprotein B-mediated neutral lipid transport from intestinal stores to stem cells and their progeny during differentiation
Lily L. Wong, Christina G. Bruxvoort, Nicholas I. Cejda, Matthew R. Delaney, Jannette Rodriguez Otero, David J. Forsthoefel   +5 more
doaj   +1 more source

Enhanced optomechanical readout using optical coalescence [PDF]

, 2013
We present a scheme to strongly enhance the readout sensitivity of the squared displacement of a mobile scatterer placed in a Fabry-P\'erot cavity.
Dantan, Aurélien, Genes, Claudiu, Pupillo, Guido, Xuereb, André   +3 more
core   +2 more sources

SLC38A6 expression in macrophages exacerbates pulmonary inflammation

Respiratory Research, 2023
Pulmonary inflammation involves complex changes of the immune cells, in which macrophages play important roles and their function might be influenced by metabolism. Slc38a6 acts as a carrier of nutrient for macrophages (Mφ) to exert the function. In this
Yizhao Peng, Weichao Chen, Fumeng Huang, Manman Geng, Xiaowei Li, Fujun Zhang, Wenhua Zhu, Liesu Meng, Rikard Holmdahl, Jing Xu, Shemin Lu   +10 more
doaj   +1 more source

RNAmmer: consistent and rapid annotation of ribosomal RNA genes

Nucleic Acids Research, 2007
The publication of a complete genome sequence is usually accompanied by annotations of its genes. In contrast to protein coding genes, genes for ribosomal RNA (rRNA) are often poorly or inconsistently annotated.
K. Lagesen, P. Hallin, E. Rødland, H. Stærfeldt, Torbjørn Rognes, D. Ussery   +5 more
semanticscholar   +1 more source