Results 21 to 30 of about 4,238,723 (297)
Nature Communications, 2020 Chronic lung diseases are characterized by molecular and cellular composition changes. Here the authors use single-cell RNA sequencing to map cell type-specific changes in human tracheal epithelium related to smoking, and to provide evidence for a tuft ...
Katherine C. Goldfarbmuren +11 more
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Genes, genes everywhere... [PDF]
Nature Reviews Cancer, 2012 Recently published papers using massively parallel sequencing to look at mutations in breast cancer provide food for thought.
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Cells, 2023 Worldwide, around 40,000 people progressively lose their eyesight as a consequence of retinitis pigmentosa (RP) caused by pathogenic variants in the ADGRV1 gene, for which currently no treatment options exist.
Merel Stemerdink +5 more
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Scientific Reports, 2017 Genetic access to small, reproducible sets of neurons is key to an understanding of the functional wiring of the brain. Here we report the generation of a new Gal4- and Cre-driver resource for zebrafish neurobiology.
Dominique Förster +14 more
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Biomolecules, 2022 Pathogenic missense variants in COCH are associated with DFNA9, an autosomal dominantly inherited type of progressive sensorineural hearing loss with or without vestibular dysfunction.
Sybren M. M. Robijn +9 more
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Nature Communications, 2022 Lipid metabolism regulates stem cell states and differentiation. Here, the authors demonstrate a requirement in planarians for Apolipoprotein B-mediated neutral lipid transport from intestinal stores to stem cells and their progeny during differentiation
Lily L. Wong +5 more
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SLC38A6 expression in macrophages exacerbates pulmonary inflammation
Respiratory Research, 2023 Pulmonary inflammation involves complex changes of the immune cells, in which macrophages play important roles and their function might be influenced by metabolism. Slc38a6 acts as a carrier of nutrient for macrophages (Mφ) to exert the function. In this
Yizhao Peng +10 more
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Gene-Gene and Gene-Environment Interactions in Mild Hyperhomocysteinemia [PDF]
Pathophysiology of Haemostasis and Thrombosis, 2003 Mild/moderate hyperhomocysteinemia (HHcy), a highly prevalent condition, is independently associated with an increased risk of arterial and venous thromboembolic diseases. Early reports of the association of mild/moderate HHcy with juvenile venous thromboembolism have shown familiarity for HHcy in relatives of index cases with thrombosis.
D'Angelo, Armando +2 more
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The Epidermis: Genes On – Genes Off
Journal of Investigative Dermatology, 1997 The epidermal keratinocyte stem cell is distinguished by a relatively undifferentiated phenotype and an ability to proliferate. As part of a carefully orchestrated process, the offspring of these stem cells lose the ability to proliferate and begin a process of morphologic and biochemical transformation that results in their conversion into corneocytes.
Richard L. Eckert +3 more
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Iatreia, 2010 Los marcadores del cromosoma X se han utilizado en identificación humana y en pruebas de paternidad desde la década de los setenta, entre los más conocidos está el antígeno de los eritrocitos "Xgª", codificado por el gen del locus Xp22.32, y algunas ...
Beatriz Martínez +7 more
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