Results 21 to 30 of about 44,113 (259)
Editorial: Neuronal ceroid lipofuscinosis: molecular genetics and epigenetics [PDF]
Frontiers in GeneticsPaschalis Nicolaou
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Genetics, Epigenetics, and Leukemia [PDF]
New England Journal of Medicine, 2010 In this issue of the Journal, Ley and colleagues1 report that somatic mutations in a gene encoding a DNA methyltransferase, DNMT3A, are common in adults with acute myeloid leukemia (AML). They also report that these mutations are associated with discrete molecular and cytogenetic features that have prognostic significance.
Kevin, Shannon, Scott A, Armstrong
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Genetics and Epigenetics in Asthma [PDF]
International Journal of Molecular Sciences, 2021 Asthma is one of the most common respiratory disease that affects both children and adults worldwide, with diverse phenotypes and underlying pathogenetic mechanisms poorly understood. As technology in genome sequencing progressed, scientific efforts were made to explain and predict asthma’s complexity and heterogeneity, and genome-wide association ...
Polyxeni Ntontsi +4 more
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Genetics, Epigenetics, Cellular Immunology, and Gut Microbiota: Emerging Links With Graves’ Disease
Frontiers in Cell and Developmental Biology, 2022 Graves’ disease (GD) is a well-known organ-specific autoimmune disease characterized by hyperthyroidism, goiter, and exophthalmos. The incidence of GD is approximately 2.0–3.0% in China and 0.5–2.0% in Western countries.
Fangyu Zhou +9 more
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BMC Women's Health, 2022 Background Abnormal uterine bleeding (AUB) is irregular menstrual bleeding which has great impact on female health and life style. Various genetic factors are involved in etiology and pathology of AUB.
Zertashia Akram +8 more
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Editorial: The genetics and epigenetics of mental health [PDF]
Frontiers in GeneticsGabriela Canalli Kretzschmar +5 more
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Interplay between Epigenetics and Genetics in Cancer [PDF]
Genomics & Informatics, 2013 Genomic instability, which occurs through both genetic mechanisms (underlying inheritable phenotypic variations caused by DNA sequence-dependent alterations, such as mutation, deletion, insertion, inversion, translocation, and chromosomal aneuploidy) and
Jae Duk Choi, Jong-Soo Lee
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Will epigenetics ever be a biosocial science? A reply to Chiapperino and Paneni
Epigenetics Communications, 2023 The recent correspondence article by Chiapperino and Paneni in Clinical Epigenetics correctly points to the inability of epigenetics to incorporate fine-grained mapping data of the individual’s surrounding milieu.
Silvio Zaina
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Scientific Reports, 2021 Tumor development involves alterations in DNA methylation patterns, which include both gains (hypermethylation) and losses (hypomethylation) in different genomic regions.
Jean S. Fain +4 more
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Can genetics guide exercise prescriptions in osteoarthritis?
Frontiers in Rehabilitation Sciences, 2022 Osteoarthritis (OA) is the most common form of arthritis and has a multifactorial etiology. Current management for OA focuses on minimizing pain and functional loss, typically involving pharmacological, physical, psychosocial, and mind-body interventions.
Osvaldo Espin-Garcia +8 more
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