Results 1 to 10 of about 27,801 (198)

Copper-Contaminated Substrate Biosorption by Penicillium sp. Isolated from Kefir Grains

open access: yesMicroorganisms, 2023
In this bioremediation study, the fungus Penicillium sp. isolated from kefir grains was evaluated for its resistance to copper in the culture medium. Penicillium sp. was cultivated in liquid medium prepared using 2% malt-agar at pH 7.0.
Antonio Ferreira de Oliveira   +10 more
doaj   +1 more source

The Protective Effects of Carvacrol on Diphenhydramine-Induced Genotoxicity in Human Peripheral Blood Lymphocytes [PDF]

open access: yesResearch Journal of Pharmacognosy, 2021
Background and Objectives: Carvacrol is a natural antioxidant possessing various biological properties. Diphenhydramine is a first-generation antihistamine prescribed for allergies and the common cold.
Mehdi Evazalipour   +4 more
doaj   +1 more source

Direct and Indirect Genotoxicity of Graphene Family Nanomaterials on DNA—A Review

open access: yesNanomaterials, 2021
Graphene family nanomaterials (GFNs), including graphene, graphene oxide (GO), reduced graphene oxide (rGO), and graphene quantum dots (GQDs), have manifold potential applications, leading to the possibility of their release into environments and the ...
Kangying Wu, Qixing Zhou, Shaohu Ouyang
doaj   +1 more source

Allelochemical Activity of Eugenol-Derived Coumarins on Lactuca sativa L.

open access: yesPlants, 2020
Coumarins are widely distributed substances in plant species that promote phytotoxic effects, allowing them to be exploited as herbicides less harmful to the environment, since many invasive species have demonstrated resistance to commercially available ...
Kamilla Pacheco Govêa   +11 more
doaj   +1 more source

Comparative study on genotoxicity methods between OECD Test guidelines and GB15193

open access: yesZhongguo shipin weisheng zazhi, 2022
ObjectiveThe purpose of this study is to compare genotoxicity methods between OECD test guidelines and China food safety standards(GB15193).MethodsMain parameters of related genotoxicity methods in OECD Testing Guidelines and GB 15193 standards were ...
ZHANG Xiaopeng   +3 more
doaj   +1 more source

Considerations for the genotoxicity assessment of middle size peptide drugs containing non-canonical amino acid residues

open access: yesGenes and Environment, 2023
Background Middle size peptides (MSPs) have emerged as a promising new pharmaceutical modality. We are seeking the best way to assess the non-clinical safety of MSPs. Consideration The requirements for assessing the genotoxicity of pharmaceuticals differ
Masayuki Mishima, Kei-ichi Sugiyama
doaj   +1 more source

Primary and Secondary Genotoxicity of Nanoparticles: Establishing a Co-Culture Protocol for Assessing Micronucleus Using Flow Cytometry

open access: yesFrontiers in Toxicology, 2022
Genotoxicity is an important endpoint to assess for understanding the risks associated with nanoparticles (NPs). Most genotoxicity studies performed on NPs have focused on primary genotoxicity analyzed by comet- or micronuclei (MN) assay using ...
N. V. Srikanth Vallabani   +1 more
doaj   +1 more source

Scientific Opinion on Flavouring Group Evaluation 215 (FGE.215): Seven α,β-Unsaturated Cinnamyl Ketones from subgroup 3.2 of FGE.19 [PDF]

open access: yesEFSA Journal, 2014
The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids of the European Food Safety Authority was requested to evaluate the genotoxic potential of flavouring substances from subgroup 3.2 of FGE.19 in the Flavouring Group Evaluation ...
EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF)
doaj   +1 more source

Scientific Opinion on Flavouring Group Evaluation 213, Revision 1 (FGE.213Rev1): Consideration of genotoxic potential for α,β-Unsaturated Alicyclic ketones and precursors from chemical subgroup 2.7 of FGE.19 [PDF]

open access: yesEFSA Journal, 2014
The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids of the European Food Safety Authority was requested to evaluate the genotoxic potential of 26 flavouring substances from subgroup 2.7 of FGE.19 in the Flavouring Group ...
EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF)
doaj   +1 more source

Thymoquinone ameliorates lead-induced suppression of the antioxidant system in rat kidneys

open access: yesLibyan Journal of Medicine, 2016
Objective: Alteration of the antioxidant status in the kidneys may be related to lead (Pb) intoxication. The present study aimed to investigate the possible beneficial effect of thymoquinone (TQ), the major active ingredient of the volatile oil of ...
Aymen Mabrouk, Hassen Ben Cheikh
doaj   +1 more source

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