Results 11 to 20 of about 27,801 (198)
Evaluation of extracts of wild Cannabis sativa L. for genotoxicity and phytochemical composition
Caryologia, 2021 Cannabis sativa L. is used as medicine and narcotic in Lesotho. Phytochemical composition and total phenolics content (TPC) for hexane, chloroform, ethyl acetate a methanol extracts of aerial parts of C. sativa were determined.
Asita Asita +3 more
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Nanomaterial genotoxicity evaluation using the high-throughput p53-binding protein 1 (53BP1) assay.
PLoS ONE, 2023 Toxicity evaluation of engineered nanomaterials is challenging due to the ever increasing number of materials and because nanomaterials (NMs) frequently interfere with commonly used assays.
Maelle Fontaine +13 more
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Is the Comet Assay a Sensitive Procedure for Detecting Genotoxicity?
Journal of Nucleic Acids, 2010 Although the Comet assay, a procedure for quantitating DNA damage in mammalian cells, is considered sensitive, it has never been ascertained that its sensitivity is higher than the sensitivity of other genotoxicity assays in mammalian cells. To determine
Satomi Kawaguchi +4 more
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Frontiers in Public Health, 2017 Genotoxicity and carcinogenicity testing of pharmaceuticals prior to commercialization is requested by regulatory agencies. The bacterial mutagenicity test was considered having the highest accuracy of carcinogenic prediction.
Qianying Liu +7 more
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The genotoxicity of caecal water from gilts following experimentally induced Fusarium mycotoxicosis
Veterinární Medicína, 2015 The examination of caecal contents allows one to investigate the exposure of colon mucosa to dietary toxins and the chemical contaminants present in animal feed.
A. Nowak +6 more
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Evaluation of genotoxicity induced by endodontic materials: A systematic review
Saudi Endodontic Journal, 2022 The ability of a substance to cause harm to the DNA molecule is known as genotoxicity. Because there is significant evidence of link between genetic damage and carcinogenesis, determining the real health hazards to patients and dental workers requires a ...
Sadaf Tamanna +3 more
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Aquaculture Reports, 2020 The use of non-plant and plant-derived anesthetics in aquaculture activities is a frequent and necessary practice to maintain fish welfare. Currently anesthetics authorized for use in aquaculture activities are limited, and the use of unauthorized ...
Hélina dos Santos Nascimento +7 more
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BIO Web of Conferences, 2021 The genotoxicity of white phosphorus was previously evaluated using the Ames test, which demonstrated the absence of toxicity. However, with all the advantages of this method, the use of the Ames test has some shortfallsin assessing genotoxicity.
Mindubaev Anton +4 more
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Toxic and genotoxic potential evaluation of soil samples by bioassays
Acta Agriculturae Slovenica, 2005 Soil samples were obtained from Slovenian industrial region Šaleška dolina and aqueous leachates were prepared. The toxicity and genotoxicity potential of these aqueous fractions have been evaluated by in vitro toxicity and genotoxicity bioassays ...
Barbara LAH +3 more
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Common Considerations for Genotoxicity Assessment of Nanomaterials
Frontiers in Toxicology, 2022 Genotoxicity testing is performed to determine potential hazard of a chemical or agent for direct or indirect DNA interaction. Testing may be a surrogate for assessment of heritable genetic risk or carcinogenic risk.
Rosalie K. Elespuru +7 more
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