Results 51 to 60 of about 2,972 (172)
The FEBS Journal, EarlyView.DNA damage in the tardigrade Hypsibius exemplaris elicits distinct cellular outcomes depending on replication status. While non‐replicating cells tolerate genotoxic stress, constitutively replicating cells undergo irreversible replication failure upon DNA damage, leading to loss of tissue homeostasis, fat depletion, sterility, and organismal death ...
Gonzalo Quiroga‐Artigas +4 more
wiley +1 more source
PLoS ONE, 2012 Mutations in the TP53 gene are the most common alterations in human tumours. TP53 mutational patterns have sometimes been linked to carcinogen exposure.
Vincent Paget +8 more
doaj +1 more source
International Journal of Cancer, Volume 159, Issue 6, Page 1360-1384, 15 September 2026.ABSTRACT Pediatric cancer is a significant cause of morbidity and mortality in children. The etiologies of pediatric cancer are largely unknown, but environmental pesticide exposures are likely to contribute. Chronic low‐dose exposure to pesticide mixtures through drinking water is a growing concern in agricultural communities.
Grace N. VanDeSteeg +4 more
wiley +1 more source
Genotoxin Effect of Composite Resin
Indonesian Journal of Legal and Forensic Sciences (IJLFS), 2019 At this moment composite resin is the most widely used material for dental restoration. The content of the resin is a mixture of monomer bisphenol A glycidyl methacrylate (Bis-GMA), trimethylene glycol dimethylmethacrylate (TEGDMA) and urethane dimethacrylate (UDMA) and special particle fillers made of radioopaque glass.
Elza Ibrahim Auerkari +1 more
openaire +2 more sources
Cell Biochemistry and Function, Volume 44, Issue 8, August 2026.ABSTRACT The role of microbes in cancer is gaining attention these days, especially in the context of tumor‐associated biofilms and dysbiotic microbiota. Biofilm‐producing microorganisms, such as Fusobacterium nucleatum and Helicobacter pylori, trigger oncogenic inflammation and immune evasion in tumor initiation and progression, and in the development
Saikat Mazumder +14 more
wiley +1 more source
Intratumoral Microbiota in Tumor: Current Understandings and Future Perspectives
MedComm, Volume 7, Issue 7, July 2026.Intratumoral bacteria are emerging as active regulators of cancer evolution rather than bystanders. This review outlines how tumor‐resident microbes drive tumor initiation and growth by inducing genomic instability, epigenetic reprogramming, oncogenic signaling, and chronic inflammation, while promoting metastatic spread via invasion, angiogenesis ...
Jiawei Chen +6 more
wiley +1 more source
Urologic Bacteriome: The Hero or the Villain in Prostate Cancer Onset, Progression, and Treatment?
Medicinal Research Reviews, Volume 46, Issue 4, Page 1111-1151, July 2026.ABSTRACT Prostate cancer (PCa) is the second most frequently diagnosed cancer in men worldwide and the fifth leading cause of cancer‐related mortality, presenting urgent unmet clinical needs in diagnosis and treatment. The recognition of the microbiome as a key factor in human health has prompted numerous studies, revealing an exciting new approach to ...
Lara R. S. Fonseca +6 more
wiley +1 more source
CA: A Cancer Journal for Clinicians, Volume 76, Issue 4, July/August 2026.Abstract This article provides updated global cancer statistics for the year 2024 based on the GLOBOCAN estimates of the International Agency for Research on Cancer. The authors describe national cancer incidence and mortality by world region and the Human Development Index and predict the burden in 2050 based on demographic trends.
Hyuna Sung +7 more
wiley +1 more source
Environmental and Molecular Mutagenesis, Volume 67, Issue 5-7, June‐August 2026.ABSTRACT There is growing interest in in vitro‐based new approach methodologies (NAMs) for assessing genotoxicity. These approaches are desirable for industries like cosmetics which are prohibited from animal testing due to regulatory restrictions, as well as “3R” considerations to avoid in vivo testing.
Ashley Allemang, Stefan Pfuhler
wiley +1 more source
Journal of Separation Science, Volume 49, Issue 6, June 2026.ABSTRACT Since the 2018 valsartan recall, the genotoxic impurity N‐nitrosodimethylamine (NDMA) has been frequently detected in various pharmaceuticals. Matrix variability often complicates routine testing, requiring customized analyses. We developed a universal LC–MS/MS method enabling consistent NDMA detection across diverse pharmaceuticals ...
Byungchan An +9 more
wiley +1 more source