Results 61 to 70 of about 2,972 (172)

Use of random amplified polymorphic DNA (RAPD) to detect DNA damage induced by Prangos ferulacea (Umbelliferae) essential oil against the Mediterranean flour moth Ephestia kuehniella Zeller (Lepidoptera: Pyralidae) [PDF]

Archives of Biological Sciences, 2015
DNA damage detection in Ephestia kuehniella by RAPD-PCR Abstract - The random amplified polymorphic DNA (RAPD) assay is a useful method for detecting genotoxin-induced DNA damage.
Ercan Fahriye Sumer
doaj   +1 more source

Fecal Microbiome Alterations in Colorectal Cancer: A Systematic Review of Compositional Changes and Microbial Biomarkers

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
Gut microbiome plays a crucial role in colorectal cancer development. The advanced sequencing techniques have the potential to complement current non‐invasive methods for early diagnosis and prevention of colorectal cancer. This includes conducting studies with robust statistical power and consistent, replicable methodologies, taking into consideration
Parvin Askari, Shirin Dashtbin, Tahereh Navidifar, Leila Dadgar‐Zankbar, Arezoo Asadi, Mahsa Ghamari, Parisa Najafi, Shabnam Zeighamy Alamdary, Roghayeh Afifirad, Roya Ghanavati, Atieh Darbandi   +10 more
wiley   +1 more source

The Role of Neonatal Ward Environment as a Reservoir for the Dissemination of Multidrug‐Resistant Klebsiella pneumoniae in Algeria

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
Whole‐genome sequencing of multidrug‐resistant Klebsiella pneumoniae from a neonatal ward environment in Chlef revealed persistent resistance genes and the clonal spread of high‐risk ST13. These findings highlight the hospital environment as a potential reservoir for transmission of resistant K. pneumoniae.
Meriem Derkaoui, Martin Alexander Fischer, Mohammed Sebaihia, Rachida Namoune, Fatiha Bouheudjeur, Meryem Beloukarif, Bakhta Madaoui, Bruno Silvester Lopes   +7 more
wiley   +1 more source

MATE transport of the E. coli-derived genotoxin colibactin [PDF]

Nature Microbiology, 2016
Various forms of cancer have been linked to the carcinogenic activities of microorganisms(1-3). The virulent gene island polyketide synthase (pks) produces the secondary metabolite colibactin, a genotoxic molecule(s) causing double-stranded DNA breaks(4) and enhanced colorectal cancer development(5,6).
Mousa, Jarrod J., Yang, Ye, Tomkovich, Sarah, Shima, Ayaka, Newsome, Rachel C., Tripathi, Prabhanshu, Oswald, Eric, Bruner, Steven D., Jobin, Christian   +8 more
openaire   +3 more sources

Typhoid Toxin of Salmonella enterica Induces ISG15 Responses Mediating Host Cell Survival and Counteracting Intracellular Infection

Molecular Microbiology, Volume 125, Issue 6, Page 475-492, June 2026.
Toxigenic Salmonella enterica exocytose the typhoid toxin during infection causing host cell DNA damage, which activates a Type‐1 Interferon‐like response characterised by interferon‐stimulated gene 15 (ISG15) expression. ISG15 was required for host cell survival during Interferon responses and suppressed intracellular growth of Salmonella. Thus, ISG15
Daniel S. Stark, Michelle King, Angela E. M. Ibler, Salma Srour, Francesca Brown, James Sheffield, Nadia Baseer, Ellen G. Vernon, Yifeng Zhang, Christopher Staples, Lilliana Radoshevich, Daniel Humphreys   +11 more
wiley   +1 more source

Gut Microbiota: A Potential Role in Modulating Carcinogenesis and Response to Anti‐Cancer Therapies

Cancer Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background The effects of microbiota on cancer are not only limited to their role in oncogenesis, progression and response to anticancer therapies; the disease itself is also influenced by microbiota. In recent investigations, alterations in the gut bacterial community between cancer patients and healthy individuals have been reported ...
Awgichew Shewasinad Yehualashet, Eleni Teklu Fersha, Berhan Begashaw Yikna, Kassahun Dires Ayenew   +3 more
wiley   +1 more source

Probiotics Cancer Interaction, Prevention, and Therapy

Immunity, Inflammation and Disease, Volume 14, Issue 5, May 2026.
ABSTRACT Cancer is a significant global health concern and ranks as the second most common cause of death on a worldwide scale. A combination of hereditary and lifestyle variables, such as diet, smoking, alcohol consumption, physical exercise, and the gut microbiota, impacts cancer development. Dysbiosis, an imbalance in gut microorganisms, can promote
Mostafa Saebi, Amir Hossein Barjasteh, Mahmoud Mahmoudi, Ramiar Kamal Kheder, Setayesh Ramazanpour, Negar Ebadpour, Afsane Fadaee, Seyed‐Alireza Esmaeili   +7 more
wiley   +1 more source

Occurrence and Control of Genotoxins in Drinking Water: A Monitoring Proposal

Journal of Public Health Research, 2016
Many studies have shown the presence of numerous organic genotoxins and carcinogens in drinking water. These toxic substances derive not only from pollution, but also from the disinfection treatments, particularly when water is obtained from surface sources and then chlorinated.
CERETTI, Elisabetta, Moretti, Massimo, ZERBINI, Ilaria, Villarini, Milena, ZANI, Claudia, Monarca, Silvano, FERETTI, Donatella   +6 more
openaire   +5 more sources

TREX2 deficiency suppresses spontaneous and genotoxin-associated mutagenesis

Cell Reports
Summary: TREX2, a 3′-5′ exonuclease, is a part of the DNA damage tolerance (DDT) pathway that stabilizes replication forks (RFs) by ubiquitinating PCNA along with the ubiquitin E3 ligase RAD18 and other DDT factors.
Teresa Marple, Mi Young Son, Xiaodong Cheng, Jun Ho Ko, Patrick Sung, Paul Hasty   +5 more
doaj   +1 more source

Host Factor Induced Bacterial Extracellular Vesicles Promote Horizontal Gene Transfer in Vibrio cholerae

Journal of Extracellular Vesicles, Volume 15, Issue 5, May 2026.
Antimicrobial stressors, that is, bile or mitomycin C, induce enlarged, nucleic acid‐rich bacterial extracellular vesicles in Vibrio cholerae that facilitate horizontal gene transfer in vitro and during intestinal colonisation. The findings provide a detailed comparison of control versus stress‐induced vesicles, identify bile as a host factor shaping ...
Dominik Fleischhacker, Yi‐Chi Chen, Noa Sanchez Gordo, Amar Cosic, Ratchara Kalwong, Leo Eberl, Stefan Schild   +6 more
wiley   +1 more source