Results 131 to 140 of about 59,169,857 (243)
Application of Genotyping-by-Sequencing in livestock and aquaculture species.
, 2016 Advances in next generation sequencing technology have increased the output/cost ratio to a level where cost effective genotyping-by-sequencing (GBS) in livestock, plants and aquaculture species is now a reality.
Ken Dodds (3501542) +5 more
core
Typical results in genotyping ALDH2 by pyrosequencing and Sanger sequencing.
, 2015 A. Three genotypes of rs671 presented different peaks by pyrosequencing. B. Genotyping results were verified by Sanger sequencing.
Lina Zhang (112887) +4 more
core +1 more source
A Critical Call for Mechanistic Investigations of Metal‐Bacteria Interactions
Advanced Materials, EarlyView.It is well established that the antibacterial properties of metals have tremendous importance for bioengineering applications. What is not as appreciated, however, is the reproducibility crisis in this field's vast literature. In this perspective, we highlight this reproducibility problem, discuss its sources, and suggest solutions towards focused ...
J. Rackwitz +9 more
wiley +1 more source
Optimisation of sequencing effort for relatedness estimation using genotyping-by-sequencing
, 2015 Genotype-based relatedness estimation underlies pedigree reconstruction, genomic selection and some association mapping methods. Genotyping-by-sequencing provides genotypes from sequencing data.
Ken Dodds (3501542) +3 more
core
Advanced Materials Technologies, EarlyView.We introduce a novel method combining microfluidics, optogenetics, and human induced pluripotent stem cell (iPSC) technology to encapsulate single iPSC‐derived cardiomyocytes (iPSC‐CMs) in an optimal environment for functional characterization. This method enables direct genotype‐phenotype correlation for genetic studies and high‐throughput screening ...
Xiao‐Ting Wang +7 more
wiley +1 more source
Advanced Science, EarlyView.Functional amyloid conversion of the translation regulator CPEB3 is essential for long‐term memory persistence. This study demonstrates that targeting this molecular switch with the anti‐amyloidogenic peptide QBP1 selectively blocks CPEB3 fibrillation without disrupting phase separation.
Paula López‐García +13 more
wiley +1 more source
Faba bean (Vicia faba L.) is an important pulse crop with a wide range of agroecological adaptations. The development of genomic tools and a comprehensive catalog of extant genetic diversity are crucial for developing improved faba bean cultivars.
Zhang, Hailin
core
, 2020 The absence of a full pedigree can hinder selective breeding efforts. In honeybees, definitive maternity and especially paternity of queens is difficult to determine, even under managedmating schemes (e.g.
Ken Dodds (3501542) +5 more
core
Rab1A Promotes Hepatic Steatosis by Suppressing Mitophagy via the Raf‐1/ERK1/2/PINK1 Signaling Axis
Advanced Science, EarlyView.Why does fat accumulate in the liver? Our study reveals Rab1A as the molecular switch that silences the cell's mitochondrial cleanup crew. Turning Rab1A off reactivates mitophagy, clears excess fat, and reverses fatty liver disease in mice—offering a promising new therapeutic target for MASLD, a growing global health challenge.
Li Zhang +9 more
wiley +1 more source
, 2019 High-throughput, inexpensive methods for extracting high-quality plant genomic DNA (gDNA) underpin deployment of next-generation sequencing marker technologies such as genotyping-by-sequencing (GBS).
Roger Moraga (517238) +8 more
core