Results 61 to 70 of about 179,331 (298)

The pattern and distribution of deleterious mutations in maize [PDF]

, 2013
Most non-synonymous mutations are thought to be deleterious because of their effect on protein sequence. These polymorphisms are expected to be removed or kept at low frequency by the action of natural selection, and rare deleterious variants have been ...
Mezmouk, Sofiane, Ross-Ibarra, Jeffrey
core   +2 more sources

Use of biostimulants for water stress mitigation in two durum wheat (Triticum durum Desf.) genotypes with different drought tolerance

Plant Stress
Agriculture is facing complex and unprecedented challenges, such as climate change and global population growth, associated with the increase of food demand. Durum wheat (DW) is a strategic crop for food security in the Mediterranean region. In this work,
Matteo Spada, Miriam Marín-Sanz, Valentina Bigini, Giulia Quagliata, Eleonora Coppa, Francisco Barro, Daniel Savatin, Roberto Ruggeri, Francesco Sestili, Francesco Rossini, Stefania Astolfi   +10 more
doaj   +1 more source

Strong isolation by distance among local populations of an endangered butterfly species (Euphydryas aurinia)

Ecology and Evolution, 2021
The marsh fritillary (Euphydryas aurinia) is a critically endangered butterfly species in Denmark known to be particularly vulnerable to habitat fragmentation due to its poor dispersal capacity.
Cino Pertoldi, Aritz Ruiz‐Gonzalez, Simon Bahrndorff, Nanna Renee Lauridsen, Thøger Nisbeth Henriksen, Anne Eskildsen, Toke Thomas Høye   +6 more
doaj   +1 more source

Analysis of Genetic Diversity and Development of A Core Collection in Walnut (Juglans regia L.) Germplasm Native to China via Genotyping-by-Sequencing

Agronomy, 2023
Popular knowledge of the population structure and genetic diversity of a plant species is essential for designing improvement strategies. The genotyping-by-sequencing (GBS) approach has been used to simplify complex genomes and has become a popular high ...
Jing Ren, Yu-An Wang, Xiao-Kang Zhou, Kai-Wen Xie, Fu-Jun Han, Hai Peng, Xiao-Yong Liu   +6 more
doaj   +1 more source

tGBS® genotyping-by-sequencing enables reliable genotyping of heterozygous loci [PDF]

Nucleic Acids Research, 2017
Conventional genotyping-by-sequencing (cGBS) strategies suffer from high rates of missing data and genotyping errors, particularly at heterozygous sites. tGBS® genotyping-by-sequencing is a novel method of genome reduction that employs two restriction enzymes to generate overhangs in opposite orientations to which (single-strand) oligos rather than ...
Ott, Alina, Liu, Sanzhen, Schnable, James C., Yeh, Cheng-Ting 'Eddy', Wang, Kai-Sin, Schnable, Patrick S.   +5 more
openaire   +2 more sources

Genotyping 1000 yeast strains by next-generation sequencing

BMC Genomics, 2013
Background The throughput of next-generation sequencing machines has increased dramatically over the last few years; yet the cost and time for library preparation have not changed proportionally, thus representing the main bottleneck for sequencing large
Wilkening Stefan, Tekkedil Manu M, Lin Gen, Fritsch Emilie S, Wei Wu, Gagneur Julien, Lazinski David W, Camilli Andrew, Steinmetz Lars M   +8 more
doaj   +1 more source

Optimization of Genotype by Sequencing data for phylogenetic purposes

MethodsX, 2020
• Herein we propose a framework for assembling and analyzing Genotype by Sequencing (GBS) data to better understand evolutionary relationships within a group of closely related species using the mastiff bats (Molossus) as our model system. Many species within this genus have low-levels of genetic variation within and between morphologically distinct ...
L.O. Loureiro, M.D. Engstrom, B.K. Lim
openaire   +3 more sources

Using genotyping-by-sequencing to understand Musa diversity [PDF]

, 2015
Poster presented at Plant and Animal Genome, PAG XXII.
Chan, A., Jacquemoud-Collet, J.P., Jenny, C., Perrier, X., Rouard, M., Roux, N., Sardos, J., Town, C.D.   +7 more
core  

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Genome-wide investigations reveal the population structure and selection signatures of Nigerian cattle adaptation in the sub-Saharan tropics

BMC Genomics, 2022
Background Cattle are considered to be the most desirable livestock by small scale farmers. In Africa, although comprehensive genomic studies have been carried out on cattle, the genetic variations in indigenous cattle from Nigeria have not been fully ...
David H. Mauki, Abdulfatai Tijjani, Cheng Ma, Said I. Ng’ang’a, Akanbi I. Mark, Oscar J. Sanke, Abdussamad M. Abdussamad, Sunday C. Olaogun, Jebi Ibrahim, Philip M. Dawuda, Godwin F. Mangbon, Rudovick R. Kazwala, Paul S. Gwakisa, Ting-Ting Yin, Yan Li, Min-Sheng Peng, Adeniyi C. Adeola, Ya-Ping Zhang   +17 more
doaj   +1 more source