Results 81 to 90 of about 58,106,402 (334)

Comparisons of improved genomic predictions generated by different imputation methods for genotyping by sequencing data in livestock populations

Journal of Animal Science and Biotechnology, 2020
Background Genotyping by sequencing (GBS) still has problems with missing genotypes. Imputation is important for using GBS for genomic predictions, especially for low depths, due to the large number of missing genotypes.
Xiao Wang, Guosheng Su, Dan Hao, Mogens Sandø Lund, Haja N. Kadarmideen   +4 more
doaj   +1 more source

Conversion of array‐based single nucleotide polymorphic markers for use in targeted genotyping by sequencing in hexaploid wheat (Triticum aestivum)

Plant Biotechnology Journal, 2017
Summary Wheat breeders and academics alike use single nucleotide polymorphisms (SNPs) as molecular markers to characterize regions of interest within the hexaploid wheat genome.
A. Burridge, Paul A. Wilkinson, M. Winfield, Gary L. A. Barker, A. Allen, J. Coghill, C. Waterfall, K. Edwards   +7 more
semanticscholar   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Wheat seed demand assessment assisted by genotyping in Ethiopia

, 2023
This study examines the extent to which wheat varieties supplied by the formal seed system align with the varieties demanded and used by farmers in Ethiopia.
Moti Jaleta, Yirga, C., Fantaye, K.T., Debello, M.J., Chilot Yirga, Bekele, A., Erenstein, O., Olaf Erenstein, Kindie Tesfaye, Endeshaw Habte, Habte, E., Adam Bekele   +11 more
core   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Low-depth genotyping-by-sequencing (GBS) in a bovine population: strategies to maximize the selection of high quality genotypes and the accuracy of imputation

BMC Genetics, 2017
BackgroundGenotyping-by-sequencing (GBS) has emerged as a powerful and cost-effective approach for discovering and genotyping single-nucleotide polymorphisms.
J. Brouard, B. Boyle, E. Ibeagha-Awemu, N. Bissonnette   +3 more
semanticscholar   +1 more source

Construction of relatedness matrices using genotyping-by-sequencing data [PDF]

BMC Genomics, 2015
Abstract Background Genotyping-by-sequencing (GBS) is becoming an attractive alternative to array-based methods for genotyping individuals for a large number of single nucleotide polymorphisms (SNPs).
Dodds, Ken G, McEwan, John C, Brauning, Rudiger, Anderson, Rayna M, van Stijn, Tracey C, Kristjánsson, Theodor, Clarke, Shannon M   +6 more
openaire   +2 more sources

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Genotyping-by-sequencing: comparison to SNP chips and whole genome sequencing

, 2015
Outline: Animal Productivity Group; Animal Genomics Team; Genomics Tool Kit; From tissue sample to breeding values; Sheep genome re-sequencing; High Density (HD) SNP Chip development; Genotyping-by-sequencing; GBS-Bioinformatics pipeline; Comparison ...
Rudiger Brauning (47247), Ken Dodds (3501542), Shannon Clarke (3504989), John McEwan (45371), Tracey Van Stijn (10380614)   +4 more
core   +1 more source

Concordance between genotyping-by-sequencing and KASP genotyping calls.

, 2013
Concordance between genotyping-by-sequencing and KASP genotyping calls.
Herman J. van Eck (411319), Theo J. A. Borm (411318), Anne-Marie A. Wolters (411316), Richard G. F. Visser (52153), Jan G. A. M. L. Uitdewilligen (411315), Bjorn B. D’hoop (411317)   +5 more
core   +1 more source