Results 131 to 140 of about 56,079,681 (305)

Bi‐ and Mono‐Allelic RFC1 Expansion in a North American Cohort With Idiopathic Axonal Neuropathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective RFC1 biallelic repeat expansion is increasingly recognized as a cause of chronic idiopathic axonal polyneuropathy (CIAP), but it remains challenging to know who to test. This study aims to determine the prevalence of biallelic and monoallelic RFC1 expansions and their corresponding neuropathy phenotypes in CIAP patients and identify ...
Amro M. Stino, Lavanya Muthukumar, Evan L. Reynolds, Peter Todd, Sinem Ovunc, Sheng Chih Jin, Zitian Tang, Simone Thomas, PNRR Study Group, Ahmet Höke, Brian C. Callaghan, Sarah Berth, Vinay Chaudhry, David Cornblath, Leana Doherty, Lindsey Hayes, Hristelina Ilieva, Thomas Lloyd, Mohammad Khoshnoodi, Brett McCray, Brett Morrison, Bipasha Mukherjee‐Clavin, Lyle Ostrow, Michael Polydefkis, Ricardo Roda, Charlotte Sumner   +25 more
wiley   +1 more source

Arterial Spin‐Labeling MRI at the Cortical‐CSF Interface: A Novel Biomarker in Alzheimer Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background/Objective Arterial spin‐labeling (ASL) MRI can measure perfusion signal adjacent to CSF spaces and may provide information regarding CSF‐adjacent water transport physiology. We developed an automated pipeline to extract cortical‐CSF interface (IF) perfusion for comparison between Alzheimer disease (AD) and cognitively normal ...
Mona Asghariahmadabad, Pouya Metanat, Michael Thomas, Luke W. Bonham, Tyson Lam, Mehmet Kurt, Hong Nguyen, Tara Ellingson, Mauro Zucchelli, Stefano Casagranda, Quin Lu, Andreas M. Rauschecker, Leo Sugrue, Luis E. Savastano, Christopher P. Hess, Kamalini Ranasinghe, S. Andrew Josephson, Bruce L. Miller, Jennifer S. Yokoyama, Gil D. Rabinovici, Peter A. Ljubenkov, Lawren VandeVrede, Kambiz Nael   +22 more
wiley   +1 more source

Optimisation of sequencing effort for relatedness estimation using genotyping-by-sequencing

, 2015
Genotype-based relatedness estimation underlies pedigree reconstruction, genomic selection and some association mapping methods. Genotyping-by-sequencing provides genotypes from sequencing data.
Ken Dodds (3501542), Rudiger Brauning (47247), Shannon Clarke (3504989), John McEwan (45371)   +3 more
core  

Predictive ability of genomic selection models in a multi-population perennial ryegrass training set using genotyping-by-sequencing

, 2022
Genomic prediction models for multi-year dry matter yield, via genotyping-by-sequencing in a composite training set, demonstrate potential for genetic gain improvement through within-half sibling family selection.
Roger Moraga (517238), Sydney Easton (15445181), Timothy Bilton (15394454), Andrew Griffiths (3440687), Marty Faville (5072459), Zulfi Jahufer (5812460), Brent Barrett (3440669), Jana Schmidt (641930), Mingshu Cao (5072465), Douglas Ryan (15397076), Rachel Tan (4605598), Siva Ganesh (607045), Philip Rolston (15403877), Jason Trethewey (15394670), Casey Flay (15396104)   +14 more
core  

Genetic diversity and population structure analysis in Asparagus officinalis

Journal of Genetic Engineering and Biotechnology
Asparagus cultivars grown worldwide are thought to have originated from a limited genetic base, however, selection has resulted in variation for climatic adaptation and other traits.
Gurleen Sidhu, Travis Banks, David Wolyn
doaj   +1 more source

Nationwide Survey of Association Between Fever and Epileptic Seizure in CDKL5 Deficiency Disorder Revealed Therapeutic Implications

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective CDKL5 deficiency disorder (CDD) is a rare, severe developmental and epileptic encephalopathy. There is a pressing need to develop effective and sustainable therapeutic strategies. We aimed to investigate the causal association between febrile episodes and epileptic seizures for therapeutic implications in CDD patients.
Siyi Wang, Jialin Du, Jinghui Liu, Dongmei Hu, Hongxin Wang, Xiaoxiao Man, Lehong Gao, Shimin Hu, Xianghong Meng, Hongyang Zhao, Minjing Hu, Yingxue Yang, Zhiqi Xiong, Liankun Ren   +13 more
wiley   +1 more source

Genotyping-By-Sequencing for diverse applications in biology

, 2016
Genotyping-by-Sequencing (GBS) is a method used to develop rapid and cost-effective high-density genetic marker data for diverse applications in biology.
Shannon Clarke (3504989), Andrew Griffiths (3440687), Rachael Ashby (15393782), Marty Faville (5072459), John McEwan (45371), Tracey Van Stijn (10380614), Rayna Anderson (3504983), Mingshu Cao (5072465), Rudiger Brauning (47247), Ken Dodds (3501542), Rachel Tan (4605598), Jeanne Jacobs (4091890), Alan McCulloch (517237)   +12 more
core  

Analysis methods for low-depth genotyping-by-sequencing data

, 2020
Outline -- Genotyping-By-Sequencing -- QC / filtering -- Relatedness & Parentage -- Allele sampling models -- Population Genetics -- Hardy-Weinberg -- FST -- Student’s ...
Ken Dodds (3501542)
core  

Concordance between genotyping-by-sequencing and KASP genotyping calls.

, 2013
Concordance between genotyping-by-sequencing and KASP genotyping calls.
Herman J. van Eck (411319), Theo J. A. Borm (411318), Anne-Marie A. Wolters (411316), Richard G. F. Visser (52153), Jan G. A. M. L. Uitdewilligen (411315), Bjorn B. D’hoop (411317)   +5 more
core   +1 more source

Nuclear and Chloroplast Markers Provide New Insights Into the Syngameon Dynamics of Genus Micromeria (Lamiaceae) in the Canary Islands

Ecology and Evolution
Species syngameons are groups of more than two hybridizing species that form complex hybrid networks. Syngameons facilitate sharing the gene pool among species while maintaining morphological differentiation.
Manuel Curto, Pamela Puppo, Harald Meimberg   +2 more
doaj   +1 more source