Results 41 to 50 of about 58,027,105 (302)

The development of a porcine 50K SNP panel using genotyping by target sequencing and its application

open access: yesJournal of Integrative Agriculture
Genotyping by target sequencing (GBTS) integrates the advantages of silicon-based technology (high stability and reliability) and genotyping by sequencing (high flexibility and cost-effectiveness). However, GBTS panels are not currently available in pigs.
Zipeng Zhang   +9 more
doaj   +1 more source

Concordant geographic and genetic structure revealed by genotyping‐by‐sequencing in a New Zealand marine isopod

open access: yesEcology and Evolution, 2020
Population genetic structure in the marine environment can be influenced by life‐history traits such as developmental mode (biphasic, with distinct adult and larval morphology, and direct development, in which larvae resemble adults) or habitat ...
William S. Pearman   +4 more
doaj   +1 more source

Sequence‐based SNP genotyping in durum wheat [PDF]

open access: yesPlant Biotechnology Journal, 2013
SummaryMarker development for marker‐assisted selection in plant breeding is increasingly based on next‐generation sequencing (NGS). However, marker development in crops with highly repetitive, complex genomes is still challenging. Here we applied sequence‐based genotyping (SBG), which couples AFLP®‐based complexity reduction to NGS, for de novo single
1. van Poecke R   +9 more
openaire   +4 more sources

Comparative Evaluation of Variant Calling Strategies for High-Density SNP Discovery in Polyploid Kiwifruit (Actinidia spp.)

open access: yesHorticulturae
Single nucleotide polymorphisms (SNPs) are widely used for genetic diversity analysis, linkage mapping, genome-wide association studies (GWAS), and molecular marker development in crop plants.
Yumi Kim, Mockhee Lee, Daeil Kim
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Use of biostimulants for water stress mitigation in two durum wheat (Triticum durum Desf.) genotypes with different drought tolerance

open access: yesPlant Stress
Agriculture is facing complex and unprecedented challenges, such as climate change and global population growth, associated with the increase of food demand. Durum wheat (DW) is a strategic crop for food security in the Mediterranean region. In this work,
Matteo Spada   +10 more
doaj   +1 more source

Genotyping 1000 yeast strains by next-generation sequencing

open access: yesBMC Genomics, 2013
Background The throughput of next-generation sequencing machines has increased dramatically over the last few years; yet the cost and time for library preparation have not changed proportionally, thus representing the main bottleneck for sequencing large
Wilkening Stefan   +8 more
doaj   +1 more source

Strong isolation by distance among local populations of an endangered butterfly species (Euphydryas aurinia)

open access: yesEcology and Evolution, 2021
The marsh fritillary (Euphydryas aurinia) is a critically endangered butterfly species in Denmark known to be particularly vulnerable to habitat fragmentation due to its poor dispersal capacity.
Cino Pertoldi   +6 more
doaj   +1 more source

Analysis of Genetic Diversity and Development of A Core Collection in Walnut (Juglans regia L.) Germplasm Native to China via Genotyping-by-Sequencing

open access: yesAgronomy, 2023
Popular knowledge of the population structure and genetic diversity of a plant species is essential for designing improvement strategies. The genotyping-by-sequencing (GBS) approach has been used to simplify complex genomes and has become a popular high ...
Jing Ren   +6 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

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