Results 41 to 50 of about 56,079,681 (305)

Concordant geographic and genetic structure revealed by genotyping‐by‐sequencing in a New Zealand marine isopod

open access: yesEcology and Evolution, 2020
Population genetic structure in the marine environment can be influenced by life‐history traits such as developmental mode (biphasic, with distinct adult and larval morphology, and direct development, in which larvae resemble adults) or habitat ...
William S. Pearman   +4 more
doaj   +1 more source

Sequence‐based SNP genotyping in durum wheat [PDF]

open access: yesPlant Biotechnology Journal, 2013
SummaryMarker development for marker‐assisted selection in plant breeding is increasingly based on next‐generation sequencing (NGS). However, marker development in crops with highly repetitive, complex genomes is still challenging. Here we applied sequence‐based genotyping (SBG), which couples AFLP®‐based complexity reduction to NGS, for de novo single
1. van Poecke R   +9 more
openaire   +4 more sources

Comparative Evaluation of Variant Calling Strategies for High-Density SNP Discovery in Polyploid Kiwifruit (Actinidia spp.)

open access: yesHorticulturae
Single nucleotide polymorphisms (SNPs) are widely used for genetic diversity analysis, linkage mapping, genome-wide association studies (GWAS), and molecular marker development in crop plants.
Yumi Kim, Mockhee Lee, Daeil Kim
doaj   +1 more source

PIMS sequencing extension:a laboratory information management system for DNA sequencing facilities [PDF]

open access: yes, 2011
Background: Facilities that provide a service for DNA sequencing typically support large numbers of users and experiment types. The cost of services is often reduced by the use of liquid handling robots but the efficiency of such facilities is hampered ...
McPherson, MJ   +18 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Use of biostimulants for water stress mitigation in two durum wheat (Triticum durum Desf.) genotypes with different drought tolerance

open access: yesPlant Stress
Agriculture is facing complex and unprecedented challenges, such as climate change and global population growth, associated with the increase of food demand. Durum wheat (DW) is a strategic crop for food security in the Mediterranean region. In this work,
Matteo Spada   +10 more
doaj   +1 more source

Genotyping 1000 yeast strains by next-generation sequencing

open access: yesBMC Genomics, 2013
Background The throughput of next-generation sequencing machines has increased dramatically over the last few years; yet the cost and time for library preparation have not changed proportionally, thus representing the main bottleneck for sequencing large
Wilkening Stefan   +8 more
doaj   +1 more source

Strong isolation by distance among local populations of an endangered butterfly species (Euphydryas aurinia)

open access: yesEcology and Evolution, 2021
The marsh fritillary (Euphydryas aurinia) is a critically endangered butterfly species in Denmark known to be particularly vulnerable to habitat fragmentation due to its poor dispersal capacity.
Cino Pertoldi   +6 more
doaj   +1 more source

Analysis of Genetic Diversity and Development of A Core Collection in Walnut (Juglans regia L.) Germplasm Native to China via Genotyping-by-Sequencing

open access: yesAgronomy, 2023
Popular knowledge of the population structure and genetic diversity of a plant species is essential for designing improvement strategies. The genotyping-by-sequencing (GBS) approach has been used to simplify complex genomes and has become a popular high ...
Jing Ren   +6 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

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