Gentamicin-induced damage to the pronephros in 96 hpf Tg(wt1b:eGFP) ZFL. [PDF]
, 2023 (A) Schematic representation of renal pronephros in 96 hpf ZFL. GL: glomerulus, PT: proximal convoluted and straight tubule, DT: distal early and late tubule. Pronephros are fused together at the midline above the yolk and heart. Transgenic expression of
Bert Müller (3004971) +10 more
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Synthesis of Gentamicin Minor Components: Gentamicin B1 and Gentamicin X2
Organic Letters, 2020 The clinical aminoglycoside antibiotic gentamicin is a mixture of several difficult-to-separate major and minor components. The relative inaccessibility of the minor components in particular complicates efforts to separate antibacterial activity from nephro- and/or ototoxicity and to clarify the origin of the potentially therapeutically important read ...
Parasuraman Rajasekaran, David Crich
openaire +3 more sources
Vancomycin acts synergistically with gentamicin against penicillin-resistant pneumococci by increasing the intracellular penetration of gentamicin [PDF]
, 2003 Vancomycin and gentamicin act synergistically against penicillin-resistant pneumococci in vitro and in experimental rabbit meningitis. The aim of the present study was to investigate the underlying mechanism of this synergism.
Cottagnoud, M +2 more
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Combinations of β-lactam or aminoglycoside antibiotics with plectasin are synergistic against methicillin-sensitive and methicillin-resistant Staphylococcus aureus. [PDF]
, 2015 Bacterial infections remain the leading killer worldwide which is worsened by the continuous emergence of antibiotic resistance. In particular, methicillin-sensitive (MSSA) and methicillin-resistant Staphylococcus aureus (MRSA) are prevalent and the ...
Coates Anthony +31 more
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Proteomic candidate biomarkers of drug-induced nephrotoxicity in the rat [PDF]
, 2012 Improved biomarkers of acute nephrotoxicity are coveted by the drug development industry, regulatory agencies, and clinicians. In an effort to identify such biomarkers, urinary peptide profiles of rats treated with two different nephrotoxins were ...
Hanig, J. +23 more
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A randomized comparison of the safety and efficacy of once-daily gentamicin or thrice-daily gentamicin in combination with ticarcillin-clavulanate [PDF]
, 1998 PURPOSE: The primary purpose of the clinical trial was to assess the safety and efficacy of once-a-day compared with three-times-a-day gentamicin in patients with serious infections who had protocol-determined peak serum aminoglycoside concentrations ...
Modin, G +7 more
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Thrombingenerierung unter Gentamicin [PDF]
, 2014 The present work examines how human coagulation is influenced by gentamicin (gentamicin×H2SO4), an often used aminoglycoside antibiotic in clinical practice.
Albert, Dada Aishe (1051975778)
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Antimicrobial activity of gentamicin in experimental enterococcal endocarditis [PDF]
, 1985 The in vitro activity of gentamicin was compared with its therapeutic efficacy in rabbits with Streptococcus faecalis endocarditis. The test strain was resistant to gentamicin as measured by MICs and MBCs determined in Mueller-Hinton broth alone or in ...
Täuber, MG +3 more
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Ingenuity pathways analysis of urine metabonomics phenotypes toxicity of gentamicin in multiple organs [PDF]
, 2010 We introduce the use of Ingenuity Pathway Analysis to analyzing global metabonomics in order to characterize phenotypically biochemical perturbations and the potential mechanisms of the gentamicin-induced toxicity in multiple organs.
Zhang, Yingzhi +11 more
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Dissociating antibacterial from ototoxic effects of gentamicin C-subtypes. [PDF]
, 2020 Gentamicin is a potent broad-spectrum aminoglycoside antibiotic whose use is hampered by ototoxic side-effects. Hospital gentamicin is a mixture of five gentamicin C-subtypes and several impurities of various ranges of nonexact concentrations.
Perez, Adela +12 more
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