Long-term follow-up of intratympanic methylprednisolone versus gentamicin in patients with unilateral Menière’s disease [PDF]
, 2018 Objectives: To determine whether long term (>48 months) symptomatic vertigo control is sustained in patients with Menie`re’s disease from a previous comparative trial of intratympanic methylprednisolone versus gentamicin, and if the two treatments remain
Bronstein, A.M. +23 more
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Controlled delivery of gentamicin using poly(3-hydroxybutyrate) microspheres [PDF]
, 2011 Poly(3-hydroxybutyrate), P(3HB), produced from Bacillus cereus SPV using a simple glucose feeding strategy was used to fabricate P(3HB) microspheres using a solid-in-oil-water (s/o/w) technique.
Boccaccini, A.R. +13 more
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Gentamicin increases the efficacy of vancomycin against penicillin-resistant pneumococci in the rabbit meningitis model [PDF]
, 2002 In experimental meningitis a single dose of gentamicin (10 mg/kg of body weight) led to gentamicin levels in around cerebrospinal fluid (CSF) of 4 mg/liter for 4 h, decreasing slowly to 2 mg/liter 4 h later.
Cottagnoud, M +3 more
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Nephroprotective Effect of Cilastatin against Gentamicin-Induced Renal Injury In Vitro and In Vivo without Altering Its Bactericidal Efficiency [PDF]
, 2020 Gentamicin is a used antibiotic that causes nephrotoxicity in 10–20% of treatment periods, which limits its use considerably. Our results have shown that cilastatin may be a promising therapeutic alternative in toxin-induced acute kidney injury ...
Juan Carlos Jado +24 more
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Serumkonsentrasjonsmåling av gentamicin hos barn [PDF]
, 2023 BAKGRUNN Gentamicin brukes ofte ved alvorlige infeksjoner hos barn. Det har vært rutine i Norge å måle serumkonsentrasjon av gentamicin rett før andre eller tredje dose (0-prøve) for å vurdere risiko for toksisitet.
Døllner, Henrik +6 more
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Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Constant Infusions vs. Intermittent Doses of Gentamicin Against Pseudomonas aeruginosa in Vitro [PDF]
, 1982 Comparative studies were performed in vitro to test the advocated superiority of infusion over intermittent injection of aminoglycosides. Pseudomonas aeruginosa was exposed to constant and to continuously decreasing (simulating in vivo kinetics ...
Wiprachtiger, Peter +7 more
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Advanced Healthcare Materials, EarlyView.What if human skin could remain fully alive and functional outside the body for weeks? A New Alternative Method (NAM) based on a vascularized full‐thickness skin microphysiological system achieves precisely this, preserving native vasculature, resident immunity, and metabolic activity for up to three weeks, while faithfully recapitulating radiation ...
Yusuf Surucu +13 more
wiley +1 more source
Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy
Advanced Materials, EarlyView.Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa +3 more
wiley +1 more source
Predictive performance of gentamicin dosing nomograms [PDF]
, 2014 Jieon Lee,1 Seonghae Yoon,1 Donghoon Shin,1 HyeKyung Han,1 Hyungmi An,1,2 Jongtae Lee,1 Kyoung Soo Lim,3 Kyung-Sang Yu,1 Howard Lee11Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul ...
Lim KS +7 more
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