Results 21 to 30 of about 161,407 (266)

Bacterial Virulence and Prevention for Human Spaceflight

Life, 2023
With the advancement in reusable rocket propulsion technology, space tourist trips into outer space are now becoming a possibility at a cost-effective rate.
Hakim Ullah Wazir, Pooja Narang, Giulia Silvani, Christine Mehner, Kate Poole, Catherine Burke, Joshua Chou   +6 more
doaj   +1 more source

Gentamicin Affects the Bioenergetics of Isolated Mitochondria and Collapses the Mitochondrial Membrane Potential in Cochlear Sensory Hair Cells

Frontiers in Cellular Neuroscience, 2019
Aminoglycoside antibiotics are widely prescribed to treat a variety of serious bacterial infections. They are extremely useful clinical tools, but have adverse side effects such as oto- and nephrotoxicity.
Molly O’Reilly, Luke Young, Nerissa K. Kirkwood, Guy P. Richardson, Corné J. Kros, Anthony L. Moore   +5 more
doaj   +1 more source

Evaluating and Improving Neonatal Gentamicin Pharmacokinetic Models Using Aggregated Routine Clinical Care Data

Pharmaceutics, 2022
Model-informed precision dosing (MIPD) can aid dose decision-making for drugs such as gentamicin that have high inter-individual variability, a narrow therapeutic window, and a high risk of exposure-related adverse events.
Dominic M. H. Tong, Jasmine H. Hughes, Ron J. Keizer   +2 more
doaj   +1 more source

A combined topical therapy of chronic dermatoses

Vestnik Dermatologii i Venerologii, 2017
The article analyzes literature sources on the etticacy ot the topical glucocorticosteroid therapy ot chronic dermatoses. Special attention is paid to evidence-based studies ot the etticacy and satety ot a combination therapy ot complicated chronic ...
N. N. Filimonkova, YE. A. Bakhlykova!
doaj   +1 more source

False aminoglycoside resistance in Enterobacterales and non-fermenters by an automated testing system: a descriptive study

Microbiology Spectrum, 2023
The majority of antimicrobial susceptibility testing (AST) in Dutch medical microbiology laboratories (MMLs) is performed using the automated system VITEK2 or Phoenix.
P. M. C. Klein Klouwenberg, W. Altorf–van der Kuil, A. J. van Griethuysen, M. Hendriks, E. J. Kuijper, D. W. Notermans, A. F. Schoffelen   +6 more
doaj   +1 more source

Protective Effect of Neutral Electrolyzed Saline on Gentamicin-Induced Nephrotoxicity: Evaluation of Histopathologic Parameters in a Murine Model

Medicina, 2023
Background and Objectives: Gentamicin (GM) is a nephrotoxic aminoglycoside. Neutral electrolyzed saline (SES) is a compound with anti-inflammatory, antioxidant, and immunomodulatory properties.
Nomely S. Aurelien-Cabezas, Brenda A. Paz-Michel, Ivan Jacinto-Cortes, Osiris G. Delgado-Enciso, Daniel A. Montes-Galindo, Ariana Cabrera-Licona, Sergio A. Zaizar-Fregoso, Juan Paz-Garcia, Gabriel Ceja-Espiritu, Valery Melnikov, Jose Guzman-Esquivel, Iram P. Rodriguez-Sanchez, Margarita L. Martinez-Fierro, Ivan Delgado-Enciso   +13 more
doaj   +1 more source

Investigation of mutations in adeR and adeS gene regions in gentamicine resistant Acinetobacter baumannii isolates

Biotechnology & Biotechnological Equipment, 2016
This study evaluated the relationship between aminoglycoside resistance and the active efflux pump and investigated the role of the active efflux pump in resistance mechanisms.
Ali Riza Atasoy, Ihsan Hakki Ciftci, Mustafa Petek, Huseyin Agah Terzi   +3 more
doaj   +1 more source

Erythropoietin; bright future and new hopes for an old drug [PDF]

Journal of Nephropathology, 2012
Recent publications have suggested renoprotective actions for erythropoietin in certain models of acute kidney injury. In a study by Rafieian-Kopaei et al., the effects of erythropoietin on amelioration of gentamicin-induced renal toxicity was ...
Mehri Kadkhodaee
doaj   +1 more source

National variation in prophylactic antibiotic use for elective primary total joint replacement: an analysis of guidelines across hospitals and trusts in the UK

Bone & Joint Open, 2023
Aims: Prophylactic antibiotic regimens for elective primary total hip and knee arthroplasty vary widely across hospitals and trusts in the UK. This study aimed to identify antibiotic prophylaxis regimens currently in use for elective primary arthroplasty
Ahmed Mabrouk, Alexander Abouharb, Gabriel Stewart, Jeya Palan, Hemant Pandit   +4 more
doaj   +1 more source

Acinetobacter baumannii Sequence Types Harboring Genes Encoding Aminoglycoside Modifying Enzymes and 16SrRNA Methylase; a Multicenter Study from Pakistan

Infection and Drug Resistance, 2020
Mohsin Khurshid,1,2 Muhammad Hidayat Rasool,2 Usman Ali Ashfaq,3 Bilal Aslam,2 Muhammad Waseem,2 Muhammad Akhtar Ali,4 Ahmad Almatroudi,5 Farhan Rasheed,6 Muhammad Saeed,2 Qinglan Guo,1 Minggui Wang1 1Institute of Antibiotics, Huashan Hospital, Fudan ...
Khurshid M, Rasool MH, Ashfaq UA, Aslam B, Waseem M, Ali MA, Almatroudi A, Rasheed F, Saeed M, Guo Q, Wang M   +10 more
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