Results 111 to 120 of about 5,161 (196)

Gephyrin is palmitoylated in vivo.

, 2014
(a) Mouse brain lysates were fractionated via ultracentrifugation and immunoblotted with gephyrin and PSD-95–specific antibodies. (b) Representative immunoblots of enriched synaptosomes after extraction with Triton X-100 or Saponin, overlayed with a ...
Borislav Dejanovic (598187), Silvia Ebert (598188), Guenter Schwarz (510946), Jochen C. Meier (598189), Marcus Semtner (249048), Franziska Neuser (424593), Tobias Lamkemeyer (159366), Bernhard Lüscher (4729437)   +7 more
core   +1 more source

Neurobeachin regulates receptor downscaling at GABAergic inhibitory synapses in a protein kinase A-dependent manner

Communications Biology
GABAergic synapses critically modulate neuronal excitability, and plastic changes in inhibitory synaptic strength require reversible interactions between GABAA receptors (GABAARs) and their postsynaptic anchor gephyrin. Inhibitory long-term potentiation (
Felix P. Lützenkirchen, Yipeng Zhu, Hans M. Maric, Dominik S. Boeck, Kira V. Gromova, Matthias Kneussel   +5 more
doaj   +1 more source

The Final Step in Molybdenum Cofactor Biosynthesis—A Historical View

Molecules
Molybdenum (Mo) is an essential micronutrient across all kingdoms of life, where it functions as a key component of the active centers of molybdenum-dependent enzymes.
Ralf R. Mendel, Kevin D. Oliphant
doaj   +1 more source

Molecular Determinants of Synaptic Function Gephyrin: does splicing affect its function? [PDF]

, 2020
Gephyrin is a protein involved in both synaptic anchoring of inhibitory ligand-gated ion channels and molybdenum cofactor synthesis. Substantial progress has been made in understanding its gene and protein structures.
I Paarmann, B. Schmitt T Saiyed, H Betz
core  

Learning-induced remodelling of inhibitory synapses in the motor cortex

Open Biology
Robust structural and functional plasticity occurs at excitatory synapses in the motor cortex in response to learning. It is well established that local spinogenesis and the subsequent maintenance of newly formed spines are crucial for motor learning ...
Nishita Bhembre, Annalisa Paolino, Sooraj S. Das, Sumasri Guntupalli, Laura R. Fenlon, Victor Anggono   +5 more
doaj   +1 more source

Vertebrate-specific sequences in the gephyrin E-domain regulate cytosolic aggregation and postsynaptic clustering

, 2007
Gephyrin is a multifunctional protein contributing to molybdenum cofactor (Moco) synthesis and postsynaptic clustering of glycine and GABA(A) receptors.
Smolinsky, B., Schwarz, G., Koenig, F., Sidler, C., Fritschy, J.M., Meier, J.C., Lardi-Studler, B., Petitjean, C.M., Smolinsky B, Petitjean CM, Fritschy JM, Koenig F, Lardi-Studler B, Schwarz G, Sidler C, Meier JC   +15 more
core   +1 more source

Gephyrin interacts with the glutamate receptor interacting protein 1 isoforms at GABAergic synapses

, 2008
We have previously shown that the glutamate receptor interacting protein 1 (GRIP1) splice forms GRIP1a/b and GRIP1c4-7 are present at the GABAergic postsynaptic complex.
Li, Rong-wen, Ali, Rashid, David R. Serwanski, Bahr, Ben A, Wendou Yu, Rong-wen Li, De Blas, Angel L, Ben A. Bahr, Angel L. De Blas, Charych, Erik I, Erik I. Charych, Yu, Wendou, Rashid Ali, Serwanski, David R   +13 more
core   +1 more source

Gephyrin [PDF]

, 2020
openaire   +1 more source

Charakterisierung der Interaktion von Gephyrin mit verschiedenen Untereinheiten des GABAA-Rezeptors [PDF]

, 2012
Die γ-Aminobuttersäure-Rezeptoren Typ A (GABAARs) sind die wesentlichen inhibitorischen Liganden-gesteuerten Ionenkanäle im zentralen Nervensystem von Vertebraten.
Kowalczyk, Sarah Katrin
core  

Stable excitatory-inhibitory synapse balance despite dynamic turnover. [PDF]

Elife
Garbett KA, Allen JP, Lopez JM, Smith CM, Sando RC.   +4 more
europepmc   +1 more source