Epigenetic markers in the embryonal germ cell development and spermatogenesis
Résumé La spermatogenèse est le processus de génération de cellules reproductrices mâles à partir de cellules souches spermatogoniales, dans l’épithélium séminifère du testicule.
Amadeusz Odroniec +2 more
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Diagnosis and management of a rare bilateral ovarian mixed germ cell tumor: a case report [PDF]
BackgroundMixed ovarian malignant germ cell tumors (MOGCTs) are rare neoplasms composed of two or more malignant germ cell components, representing less than 1% of all ovarian germ cell tumors.
Xuanling Li +6 more
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A rare case of pure-type embryonal carcinoma in a 75-year-old woman mimicking epithelial ovarian carcinoma [PDF]
Embryonal carcinoma, a very rare ovarian germ cell tumor, involves pure and mixed phenotypes. Pure-type embryonal carcinoma has never been reported in postmenopausal women. The current case was, thus, misdiagnosed as an epithelial ovarian carcinoma based
Hyun Been Jo +7 more
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Survival of Testicular Pure Embryonal Carcinoma vs. Mixed Germ Cell Tumor Patients across All Stages
Background and Objectives: The impact of pure histological subtypes in testicular non-seminoma germ cell tumors on survival, specifically regarding pure embryonal carcinoma, is not well established.
Cristina Cano Garcia +19 more
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Mixed Germ Cell Tumour in an Infertile Male Having Unilateral Cryptorchidism: A Rare Case Report [PDF]
Mixed germ cell tumours with multiple components occur more frequently than the pure varieties of germ cell tumours. Embryonal carcinoma and teratoma together form the most common components of the mixed germ cell tumour but the yolk sac tumour is ...
Anand Singla +3 more
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Introduction: sacrococcygeal teratoma (TSC) is the most common tumor of the neonatal period. Alphafetoprotein is an important tumor marker and is used in the follow-up period as a marker of malignancy.
VANESSA DO NASCIMENTO SANTOS +2 more
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Molecular and epigenetic pathogenesis of germ cell tumors
The development of germ cell tumors (GCTs) is a unique pathogenesis occurring at an early developmental stage during specification, migration or colonization of primordial germ cells (PGCs) in the genital ridge.
Melanie R. Müller +3 more
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Germ cells from mouse and human embryonic stem cells [PDF]
Mammalian gametes are derived from a founder population of primordial germ cells (PGCs) that are determined early in embryogenesis and set aside for unique development. Understanding the mechanisms of PGC determination and differentiation is important for elucidating causes of infertility and how endocrine disrupting chemicals may potentially increase ...
Behrouz, Aflatoonian, Harry, Moore
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LINEing germ and embryonic stem cells’ silencing of retrotransposons [PDF]
Almost half of our genome is occupied by transposable elements. Although most of them are inactive, one type of non-long terminal repeat (LTR) retrotransposon, long interspersed nuclear element 1 (LINE1), is capable of retrotransposition. Two studies in this issue, Pezic and colleagues (pp. 1410–1428) and Castro-Diaz and colleagues (pp.
T. Ishiuchi, M.-E. Torres-Padilla
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Porcine Germ Cells Phenotype during Embryonic and Adult Development
Primordial germ cells (PGCs) are the precursors of gametes. Due to their importance for the formation and reproduction of an organism, understanding the mechanisms and pathways of PGCs and the differences between males and females is essential. However, there is little research in domestic animals, e.g., swine, regarding the epigenetic and pluripotency
Amanda Soares Jorge +10 more
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