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Embryonal rhabdomyosarcoma arising in a germ cell tumour
Medical and Pediatric Oncology, 1994Alan Horwich, R Pinkerton
exaly +5 more sources
Testicular cancer is preceded by the noninvasive stage of carcinoma in situ (CIS). According to a recent hypothesis, testicular CIA cells are germ cells transformed in fetal life. The idea of an embryonal origin of testicular germ cell neoplasia would be
Peter W Andrews +2 more
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Human embryonic stem cell and embryonic germ cell lines
Trends in Biotechnology, 2000Undifferentiated human embryonic stem (ES) cells and embryonic germ (EG) cells can be cultured indefinitely and yet maintain the potential to form many or all of the differentiated cells in the body. Human ES and EG cells provide an exciting new model for understanding the differentiation and function of human tissue, offer new strategies for drug ...
J A, Thomson, J S, Odorico
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Embryonic Germ Cells: When Germ Cells Become Stem Cells
Seminars in Reproductive Medicine, 2006Embryonic germ cells (EGCs) are pluripotent stem cells derived from primordial germ cells (PGCs). PGCs are progenitors of adult gametes, which diverge from the somatic lineage between late embryonic to early fetal development. First derived in the mouse, EGCs have also been derived from human, chicken, and pig.
Candace L, Kerr +3 more
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Reprogramming Primordial Germ Cells (PGC) to Embryonic Germ (EG) Cells
Current Protocols in Stem Cell Biology, 2008AbstractIn this unit we describe the derivation of pluripotent embryonic germ (EG) cells from mouse primordial germ cells (PGCs) isolated from both 8.5‐ and 11.5‐days post‐coitum (dpc) embryos. Once EG cells are derived we explain how to propagate and characterize the cell lines.
Gabriela, Durcova-Hills, Azim, Surani
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Histogenesis of intracranial germ cell tumors: primordial germ cell vs. embryonic stem cell
Child's Nervous System, 2023Intracranial germ cell tumor (iGCT) is a rare disorder and often occurs during childhood and adolescence. iGCTs are frequently localized in pineal region and hypothalamic-neurohypophyseal axis (HNA). In spite of well-established clinical and pathological entity, histogenesis of iGCTs remains unsettled.
Emma L, Burnham, Tadanori, Tomita
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Human primordial germ cells and embryonic germ cells, and their use in cell therapy
Current Opinion in Biotechnology, 2005Human embryonic germ (hEG) cells derive from the transformation of primordial germ cells (PGCs) under appropriate culture conditions with embryonic fibroblast feeder cells. Although the pluripotent and proliferative capacity of hEG cells is thought to be equivalent to that of human embryonic stem (hES) cells, the difficulties of isolating and ...
Behrouz, Aflatoonian, Harry, Moore
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Isolation and Culture of Embryonic Germ Cells
2003Publisher Summary In mammals, three types of pluripotent stem cells have been identified and isolated into culture; these are embryonic stem (ES) cells, embryonic germ (EG) cells, and embryonal carcinoma (EC) cells. These pluripotent stem cells share two important properties.
Maria P, De Miguel, Peter J, Donovan
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Serum-free culture of murine primordial germ cells and embryonic germ cells
Theriogenology, 2003Fetal calf serum (FCS) has usually been used for culture of embryonic stem (ES) cell as a component of the culture medium. However, FCS contains undefined factors, which promote cell proliferation and occasionally stimulate differentiation of ES cells. Recently, a chemically-defined serum replacement, Knockout Serum Replacement (KSR), was developed to ...
Takuro, Horii +3 more
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