Results 271 to 280 of about 12,778 (301)
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[Germ cell and embryonal tumors].
Der Radiologe, 2015Germ cell tumors, which constitute approximately 3-5% of tumors of the central nervous system (CNS), can be subdivided into germinomas, embryonal carcinomas, yolk sac tumors, choriocarcinomas, teratomas and mixed germ cell tumors. The diagnosis of intracranial germ cell tumor is based on the clinical symptoms, detection of tumor markers, such as alpha ...
W, Reith +3 more
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PDGF mediates derivation of human embryonic germ cells
Differentiation, 2013Human embryonic germ cells (hEGCs) are a valuable and underutilized source of pluripotent stem cells. Unlike embryonic stem cells, which have been extensively studied, little is known about the factors that regulate hEGC derivation and maintenance. This study demonstrates for the first time a central role for selective activation of PDGFR signaling in ...
Yang, Li +12 more
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Epigenotype switching of imprintable loci in embryonic germ cells
Development Genes and Evolution, 1998Expression of imprinted genes is dependent on their parental origin. This is reflected in the heritable differential methylation of parental alleles. The gametic imprints are however reversible as they do not endure for more than one generation. To investigate if the epigenetic changes in male and female germ line are similar or not, we derived ...
T, Tada +6 more
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Germ layer induction from embryonic stem cells
Experimental Hematology, 2005Embryonic stem (ES) cells have the potential to develop into all cell types of the adult body. This capability provides the basis for considering the ES cell system as a novel and unlimited source of cells for replacement therapies for the treatment of a wide range of diseases.
Paul, Gadue +4 more
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Derivation and characterization of pluripotent embryonic germ cells in chicken
Molecular Reproduction and Development, 2000Embryonic germ (EG) cell lines established from primordial germ cells (PGCs) are undifferentiated and pluripotent stem cells. To date, EG cells with proven germ-line transmission have been completely established only in the mouse with embryonic stem (ES) cells.
T S, Park, J Y, Han
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Effects of Irradiation on Germ Cells and Embryonic Development in Teleosts
1979Publisher Summary This chapter discusses the effects of irradiation on germ cells and embryonic development in teleosts. Sterility and weight reduction of testes after irradiation are mainly because of actual cell loss, and the order of decreasing sensitivity of spermatogenic cells is from the most sensitive spermatogonia, through primary and ...
N, Egami, K I, Ijiru
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Directed neural differentiation of duck embryonic germ cells
Journal of Cellular Biochemistry, 2011AbstractAlthough the avian primordial germ cells (PGCs) have been used to produce transgenic birds, their characteristics largely remain unknown. The isolation, culture, biological characterization, and directed neural differentiation of duck EG cells were assayed in this study. The Results showed that the EG cells were got by isolating embryonic gonad
Lin-Feng, Li +4 more
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[Germ cells in the murine embryonic development].
Yi chuan = Hereditas, 2005This paper reviewed the recent progress of the origin, migration and proliferation, sex determination, and genomic modification of murine germ cells during its embryonic development. Murine germ cells originate from primordial germ cells at about 7-7.5dpc.
Rong, Han, Ke-gang, Shang
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The control of the differentiation of female embryonic germ cells in the bird
Developmental Biology, 1974Abstract The left gonad from female chick embryos at 4–12 days of incubation was cultured in vitro as pieces of intact gonad, pieces of isolated cortex, and groups of pure germ cells. All cultures were maintained for a time equal to 17 days in ovo . At the end of the culture period, a cytological and quantitative study was made on the germ cells.
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Embryonic germ cell lines and their derivation from mouse primordial germ cells.
Ciba Foundation symposium, 1995When primordial germ cells of the mouse are cultured on feeder layers with the addition of the polypeptide signalling molecules leukaemia inhibitory factor, Steel factor and basic fibroblast growth factor they give rise to cells that resemble undifferentiated blastocyst-derived embryonic stem cells.
P A, Labosky, D P, Barlow, B L, Hogan
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