Results 21 to 30 of about 20,940 (309)

Pure Embryonal Cell Carcinoma: A Rare Entity [PDF]

Journal of Clinical and Diagnostic Research, 2023
Malignancy of the testes constitutes only one percent of all male cancers. Most testicular malignancies are Germ Cell Tumours (GCTs), which are broadly categorised into seminomatous and non-seminomatous types. Non seminomatous GCTs are further classified
Neha Jaiswal, Anita Sajjanar, Vaishnavi Mishra   +2 more
doaj   +1 more source

Primary Germ Cell Tumors of the Mediastinum: 10 Years of Experience in a Tertiary Teaching Hospital

Kaohsiung Journal of Medical Sciences, 2005
Germ cell tumors occur mostly in the gonad. Extragonadal germ cell tumors are rare, and most occur in the retroperitoneum and mediastinum. Primary mediastinal germ cell tumors are often found in the anterior portion of the mediastinum and include ...
Chih-Jen Yang, Meng-Shuan Cheng, Ming-Shyan Huang   +2 more
doaj   +1 more source

Prognostic factors in children with extracranial germ cell tumors treated with cisplatin-based chemotherapy [PDF]

Korean Journal of Pediatrics, 2015
PurposeTo evaluate the outcomes and prognostic factors in children with extracranial germ cell tumors (GCTs) treated at a single institution.MethodsSixty-six children diagnosed with extracranial GCTs between 1996 and 2012 were included in the study ...
Jinsup Kim, Na Hee Lee, Soo Hyun Lee, Keon Hee Yoo, Ki Woong Sung, Hong Hoe Koo, Jeong-Meen Seo, Suk-Koo Lee   +7 more
doaj   +1 more source

Hematopoietic progenitors express embryonic stem cell and germ layer genes [PDF]

Comptes Rendus. Biologies, 2011
Cell therapy for tissue regeneration requires cells with high self-renewal potential and with the capacity to differentiate into multiple differentiated cell lineages, like embryonic stem cells (ESCs) and adult somatic cells induced to pluripotency (iPSCs) by genetic manipulation.
Bernard, Pessac, Mehdi Ait, Bara, David, Ford, Gopi K, Patibandla, David, Trisler   +4 more
openaire   +2 more sources

Primate Primordial Germ Cells Acquire Transplantation Potential by Carnegie Stage 23. [PDF]

, 2017
Primordial germ cells (PGCs) are the earliest embryonic progenitors in the germline. Correct formation of PGCs is critical to reproductive health as an adult.
Chen, Di, Clark, Amander T, Gkountela, Sofia, Hennebold, Jon D, Liu, Wanlu, Orwig, Kyle E, Sosa, Enrique, Sukhwani, Meena   +7 more
core   +2 more sources

Giant Mediastinal Germ Cell Tumour: An Enigma of Surgical Consideration

Case Reports in Surgery, 2016
We present a case of 16-year-old male, who was referred from private centre for dyspnoea, fatigue, and orthopnea. The chest radiograph revealed complete opacification of left chest which was confirmed by computed tomography as a large left mediastinal ...
Firdaus Hayati, Nurayub Mohd Ali, Levin Kesu Belani, Nornazirah Azizan, Andee Dzulkarnaen Zakaria, Mohd Ramzisham Abdul Rahman   +5 more
doaj   +1 more source

Evaluating Human Embryonic Germ Cells: Concord and Conflict as Pluripotent Stem Cells

Stem Cells, 2005
AbstractThe realization of cell replacement therapy derived from human pluripotent stem cells requires full knowledge of the starting cell types as well as their differentiated progeny. Alongside embryonic stem cells, embryonic germ cells (EGCs) are an alternative source of pluripotent stem cell. Since 1998, four groups have described the derivation of
Turnpenny, Lee W., Spalluto, Cosma M., Perrett, Rebecca M., O'Shea, Marie, Piper Hanley, Karen, Cameron, Iain T., Wilson, David I., Hanley, Neil A.   +7 more
openaire   +4 more sources

Treatment of CD30-Expressing Germ Cell Tumors and Sex Cord Stromal Tumors with Brentuximab Vedotin: Identification and Report of Seven Cases [PDF]

, 2017
BACKGROUND: Cytotoxic therapy for relapsed and refractory germ cell tumors or metastatic sex cord stromal tumors is rarely effective and is often accompanied by high adverse event rates.
Albany, Costantine, Boyd, Thomas, Einhorn, Lawrence, Feldman, Darren R., Garbo, Lawrence, Josephson, Neil   +5 more
core   +1 more source

Specific detection of OCT3/4 isoform A/B/B1 expression in solid (germ cell) tumours and cell lines: Confirmation of OCT3/4 specificity for germ cell tumours [PDF]

, 2011
Background: OCT3/4 (POU5F1) is an established diagnostic immunohistochemical marker for specific histological variants of human malignant germ cell tumours (GCTs), including the seminomatous types and the stem cell component of non-seminomas, known as ...
A J M Gillis, A M Hoogland, AJ Gillis, AT Collins, BR Krishnan, CJ Lengner, D Pain, DC Hay, DM Lai, G J L H van Leenders, G Jenster, G Suo, H A D M van Herk, H Niwa, H Stoop, H Zaehres, J de Jong, J de Jong, J de Jong, J de Jong, J de Jong, J Kehler, J Lee, J Martens, J Takeda, JM Velkey, JW Oosterhuis, KJ Livak, L Cheng, L H J Looijenga, L Looijenga, L Poliseno, L Ricci-Vitiani, LH Looijenga, LHJ Looijenga, M A Rijlaarsdam, M Pesce, M Pesce, M Timmermans, MH Asadi, MH Tai, MM Matin, N Xu, NJ van Casteren, P Sotomayor, PW Andrews, RA Sturm, RB Marques, S Liedtke, S Liedtke, S Zhao, SI Papamichos, SK Hussain, T Cantz, UI Ezeh, V Botquin, W Dinjens, WM van Weerden, X Wang, Y Atlasi, Y Atlasi, Y Gao, YC Chen   +62 more
core   +3 more sources

POU5F1 (OCT3/4) identifies cells with pluripotent potential in human germ cell tumors [PDF]

, 2003
Human germ cell tumors (GCTs) may have variable histology and clinical behavior, depending on factors such as sex of the patient, age at clinical diagnosis, and anatomical site of the tumor.
Bokemeyer, C., Dekken, H. (Herman) van, Gillis, A.J.M. (Ad), Gouveia Brazao, C.A. de, Honecker, F.U. (Friedemann), Kononen, J., Leeuw, H.P. de, Looijenga, L.H.J. (Leendert), Oosterhuis, J.W. (Wolter), Perlman, E.J., Roozendaal, K.E. (Kees) van, Sauter, G., Schneider, D.T. (Dominik), Stoop, J.A. (Hans), Weber, R.F.A. (Robert), Wolffenbuttel, K.P. (Katja), Zoelen, E.J.J. (Everardus) van   +16 more
core   +12 more sources