Results 21 to 30 of about 24,196 (383)

Mixed Germ Cell Tumour in an Infertile Male Having Unilateral Cryptorchidism: A Rare Case Report [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2016
Mixed germ cell tumours with multiple components occur more frequently than the pure varieties of germ cell tumours. Embryonal carcinoma and teratoma together form the most common components of the mixed germ cell tumour but the yolk sac tumour is ...
Anand Singla   +3 more
doaj   +1 more source

Updating germ cell tumour pathogenesis – the ability of seminomas for FOXA2‐driven extra‐embryonic differentiation

open access: yesHistopathology, 2023
Testicular germ cell tumours are the most common solid malignancies in young men of age 14–44 years. It is generally accepted that both seminomas and non‐seminomas arise from a common precursor, the germ cell neoplasia in‐situ, which itself is the result
F. Bremmer   +3 more
semanticscholar   +1 more source

Sacrococcygeal teratoma: evaluation of its approach, treatment and follow-up in two reference children cancer centers in Brazil / Rio de Janeiro

open access: yesRevista do Colégio Brasileiro de Cirurgiões, 2022
Introduction: sacrococcygeal teratoma (TSC) is the most common tumor of the neonatal period. Alphafetoprotein is an important tumor marker and is used in the follow-up period as a marker of malignancy.
VANESSA DO NASCIMENTO SANTOS   +2 more
doaj   +2 more sources

Molecular and epigenetic pathogenesis of germ cell tumors

open access: yesAsian Journal of Urology, 2021
The development of germ cell tumors (GCTs) is a unique pathogenesis occurring at an early developmental stage during specification, migration or colonization of primordial germ cells (PGCs) in the genital ridge.
Melanie R. Müller   +3 more
doaj   +1 more source

T cells in testicular germ cell tumors: new evidence of fundamental contributions by rare subsets

open access: yesbioRxiv, 2023
BACKGROUND Immune cell infiltration is heterogeneous but common in testicular germ cell tumors (TGCT) and pre-invasive germ cell neoplasia in situ (GCNIS).
Rashidul Islam   +20 more
semanticscholar   +1 more source

Germ cells from mouse and human embryonic stem cells [PDF]

open access: yesReproduction, 2006
Mammalian gametes are derived from a founder population of primordial germ cells (PGCs) that are determined early in embryogenesis and set aside for unique development. Understanding the mechanisms of PGC determination and differentiation is important for elucidating causes of infertility and how endocrine disrupting chemicals may potentially increase ...
Behrouz, Aflatoonian, Harry, Moore
openaire   +2 more sources

Comprehensive characteristics of pathological subtypes in testicular germ cell tumor: Gene expression, mutation and alternative splicing

open access: yesFrontiers in Immunology, 2023
Background Testicular germ cell tumor (TGCT) is the most common tumor in young men, but molecular signatures, especially the alternative splicing (AS) between its subtypes have not yet been explored.
Xiangyang Yao   +6 more
semanticscholar   +1 more source

Metachronous Testicular Mixed Germ Cell Tumour and Gastric Marginal Zone Lymphoma: A Case Report with An Unusual Association

open access: yesAnnals of Pathology and Laboratory Medicine, 2023
Background Second primary malignancies (SPMs), irrespective of location, are characterized by two or more distinct neoplasms in the same patient. Gastric marginal zone lymphoma of mucosa-associated lymphoid tissue (MZL) shows a higher risk of developing
Mayur Parkhi   +3 more
semanticscholar   +1 more source

LINEing germ and embryonic stem cells’ silencing of retrotransposons [PDF]

open access: yesGenes & Development, 2014
Almost half of our genome is occupied by transposable elements. Although most of them are inactive, one type of non-long terminal repeat (LTR) retrotransposon, long interspersed nuclear element 1 (LINE1), is capable of retrotransposition. Two studies in this issue, Pezic and colleagues (pp. 1410–1428) and Castro-Diaz and colleagues (pp.
T. Ishiuchi, M.-E. Torres-Padilla
openaire   +2 more sources

Testis-expressed gene 11 inhibits cisplatin-induced DNA damage and contributes to chemoresistance in testicular germ cell tumor

open access: yesScientific Reports, 2022
Testicular germ cell tumor (TGCT) is a rare cancer but the most common tumor among adolescent and young adult males. Patients with advanced TGCT often exhibit a worse prognosis due to the acquisition of therapeutic resistance.
Sachi Kitayama   +6 more
semanticscholar   +1 more source

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