Results 51 to 60 of about 24,196 (383)

Giant Mediastinal Germ Cell Tumour: An Enigma of Surgical Consideration

open access: yesCase Reports in Surgery, 2016
We present a case of 16-year-old male, who was referred from private centre for dyspnoea, fatigue, and orthopnea. The chest radiograph revealed complete opacification of left chest which was confirmed by computed tomography as a large left mediastinal ...
Firdaus Hayati   +5 more
doaj   +1 more source

Treatment of CD30-Expressing Germ Cell Tumors and Sex Cord Stromal Tumors with Brentuximab Vedotin: Identification and Report of Seven Cases [PDF]

open access: yes, 2017
BACKGROUND: Cytotoxic therapy for relapsed and refractory germ cell tumors or metastatic sex cord stromal tumors is rarely effective and is often accompanied by high adverse event rates.
Albany, Costantine   +5 more
core   +1 more source

Evaluating Human Embryonic Germ Cells: Concord and Conflict as Pluripotent Stem Cells

open access: yesStem Cells, 2005
AbstractThe realization of cell replacement therapy derived from human pluripotent stem cells requires full knowledge of the starting cell types as well as their differentiated progeny. Alongside embryonic stem cells, embryonic germ cells (EGCs) are an alternative source of pluripotent stem cell. Since 1998, four groups have described the derivation of
Turnpenny, Lee W.   +7 more
openaire   +4 more sources

Specific detection of OCT3/4 isoform A/B/B1 expression in solid (germ cell) tumours and cell lines: Confirmation of OCT3/4 specificity for germ cell tumours [PDF]

open access: yes, 2011
Background: OCT3/4 (POU5F1) is an established diagnostic immunohistochemical marker for specific histological variants of human malignant germ cell tumours (GCTs), including the seminomatous types and the stem cell component of non-seminomas, known as ...
A J M Gillis   +62 more
core   +3 more sources

Malignant Ovarian Mixed Germ Cell Tumor: a Rare Case [PDF]

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2009
Background and Objectives: Mixed germ cell tumors of the ovary, uncommon but aggressive tumors are seen most often in young women or adolescent girls, and are generally curable if found and treated early.
Z. Ebrahimi, Z. Khalaji Nia
doaj   +2 more sources

A Case of Sarcoidosis Disseminated to Skeletal Tissues

open access: yesInternational Journal of Medical Students, 2013
Sarcoidosis is a systemic granulomatous disease of unknown etiology that typically affects young adults. Diagnostic criteria for sarcoidosis include involvement of two or more of the following organ systems: 1) pulmonary infiltrates; 2) bilateral hilar ...
Edon Rabinowitz   +2 more
doaj   +1 more source

Germ Cell Tumor Presenting with Precocious Puberty in a Girl in United Arab Emirates

open access: yesDubai Medical Journal, 2020
We herein report a rare case of malignant mixed germ cell tumor comprising both an embryonal carcinoma (60%) and a yolk sac tumor (40%). A 7-year-old girl presented to the emergency department with persistent vaginal bleeding, abdominal pain, and ...
Asim Noor Rana   +4 more
doaj   +1 more source

Rhabdomyosarcoma: Advances in Molecular and Cellular Biology. [PDF]

open access: yes, 2015
Rhabdomyosarcoma (RMS) is the most common soft tissue malignancy in childhood and adolescence. The two major histological subtypes of RMS are alveolar RMS, driven by the fusion protein PAX3-FKHR or PAX7-FKHR, and embryonic RMS, which is usually ...
Duan, Zhenfeng   +5 more
core   +3 more sources

Integrated Molecular Characterization of Testicular Germ Cell Tumors

open access: yesCell Reports, 2018
Summary: We studied 137 primary testicular germ cell tumors (TGCTs) using high-dimensional assays of genomic, epigenomic, transcriptomic, and proteomic features. These tumors exhibited high aneuploidy and a paucity of somatic mutations.
Hui Shen   +240 more
doaj   +1 more source

The present and future of serum diagnostic tests for testicular germ cell tumours. [PDF]

open access: yes, 2016
Testicular germ cell tumours (GCTs) are the most common malignancy occurring in young adult men and the incidence of these tumours is increasing. Current research priorities in this field include improving overall survival for patients classified as ...
A Lorch   +72 more
core   +2 more sources

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