Results 51 to 60 of about 24,196 (383)
Giant Mediastinal Germ Cell Tumour: An Enigma of Surgical Consideration
Case Reports in Surgery, 2016 We present a case of 16-year-old male, who was referred from private centre for dyspnoea, fatigue, and orthopnea. The chest radiograph revealed complete opacification of left chest which was confirmed by computed tomography as a large left mediastinal ...Firdaus Hayati, Nurayub Mohd Ali, Levin Kesu Belani, Nornazirah Azizan, Andee Dzulkarnaen Zakaria, Mohd Ramzisham Abdul Rahman +5 moredoaj +1 more sourceTreatment of CD30-Expressing Germ Cell Tumors and Sex Cord Stromal Tumors with Brentuximab Vedotin: Identification and Report of Seven Cases [PDF]
, 2017 BACKGROUND:
Cytotoxic therapy for relapsed and refractory germ cell tumors or metastatic sex cord stromal tumors is rarely effective and is often accompanied by high adverse event rates.Albany, Costantine, Boyd, Thomas, Einhorn, Lawrence, Feldman, Darren R., Garbo, Lawrence, Josephson, Neil +5 morecore +1 more sourceEvaluating Human Embryonic Germ Cells: Concord and Conflict as Pluripotent Stem Cells
Stem Cells, 2005 AbstractThe realization of cell replacement therapy derived from human pluripotent stem cells requires full knowledge of the starting cell types as well as their differentiated progeny. Alongside embryonic stem cells, embryonic germ cells (EGCs) are an alternative source of pluripotent stem cell. Since 1998, four groups have described the derivation of Turnpenny, Lee W., Spalluto, Cosma M., Perrett, Rebecca M., O'Shea, Marie, Piper Hanley, Karen, Cameron, Iain T., Wilson, David I., Hanley, Neil A. +7 moreopenaire +4 more sourcesSpecific detection of OCT3/4 isoform A/B/B1 expression in solid (germ cell) tumours and cell lines: Confirmation of OCT3/4 specificity for germ cell tumours [PDF]
, 2011 Background: OCT3/4 (POU5F1) is an established diagnostic immunohistochemical marker for specific histological variants of human malignant germ cell tumours (GCTs), including the seminomatous types and the stem cell component of non-seminomas, known as ...A J M Gillis, A M Hoogland, AJ Gillis, AT Collins, BR Krishnan, CJ Lengner, D Pain, DC Hay, DM Lai, G J L H van Leenders, G Jenster, G Suo, H A D M van Herk, H Niwa, H Stoop, H Zaehres, J de Jong, J de Jong, J de Jong, J de Jong, J de Jong, J Kehler, J Lee, J Martens, J Takeda, JM Velkey, JW Oosterhuis, KJ Livak, L Cheng, L H J Looijenga, L Looijenga, L Poliseno, L Ricci-Vitiani, LH Looijenga, LHJ Looijenga, M A Rijlaarsdam, M Pesce, M Pesce, M Timmermans, MH Asadi, MH Tai, MM Matin, N Xu, NJ van Casteren, P Sotomayor, PW Andrews, RA Sturm, RB Marques, S Liedtke, S Liedtke, S Zhao, SI Papamichos, SK Hussain, T Cantz, UI Ezeh, V Botquin, W Dinjens, WM van Weerden, X Wang, Y Atlasi, Y Atlasi, Y Gao, YC Chen +62 morecore +3 more sourcesA Case of Sarcoidosis Disseminated to Skeletal Tissues
International Journal of Medical Students, 2013 Sarcoidosis is a systemic granulomatous disease of unknown etiology that typically affects young adults. Diagnostic criteria for sarcoidosis include involvement of two or more of the following organ systems: 1) pulmonary infiltrates; 2) bilateral hilar ...Edon Rabinowitz, Chinwe Ogedegbe, Joseph Feldman +2 moredoaj +1 more sourceRhabdomyosarcoma: Advances in Molecular and Cellular Biology. [PDF]
, 2015 Rhabdomyosarcoma (RMS) is the most common soft tissue malignancy in childhood and adolescence. The two major histological subtypes of RMS are alveolar RMS, driven by the fusion protein PAX3-FKHR or PAX7-FKHR, and embryonic RMS, which is usually ...Duan, Zhenfeng, Guo, Wei, Hornicek, Francis J, Mankin, Henry J, Shen, Jacson K, Sun, Xin +5 morecore +3 more sourcesIntegrated Molecular Characterization of Testicular Germ Cell Tumors
Cell Reports, 2018 Summary: We studied 137 primary testicular germ cell tumors (TGCTs) using high-dimensional assays of genomic, epigenomic, transcriptomic, and proteomic features. These tumors exhibited high aneuploidy and a paucity of somatic mutations.Hui Shen, Juliann Shih, Daniel P. Hollern, Linghua Wang, Reanne Bowlby, Satish K. Tickoo, Vésteinn Thorsson, Andrew J. Mungall, Yulia Newton, Apurva M. Hegde, Joshua Armenia, Francisco Sánchez-Vega, John Pluta, Louise C. Pyle, Rohit Mehra, Victor E. Reuter, Guilherme Godoy, Jeffrey Jones, Carl S. Shelley, Darren R. Feldman, Daniel O. Vidal, Davor Lessel, Tomislav Kulis, Flavio M. Cárcano, Kristen M. Leraas, Tara M. Lichtenberg, Denise Brooks, Andrew D. Cherniack, Juok Cho, David I. Heiman, Katayoon Kasaian, Minwei Liu, Michael S. Noble, Liu Xi, Hailei Zhang, Wanding Zhou, Jean C. ZenKlusen, Carolyn M. Hutter, Ina Felau, Jiashan Zhang, Nikolaus Schultz, Gad Getz, Matthew Meyerson, Joshua M. Stuart, Rehan Akbani, David A. Wheeler, Peter W. Laird, Katherine L. Nathanson, Victoria K. Cortessis, Katherine A. Hoadley, Linghua Wang, Liu Xi, David Wheeler, Daniel Hughes, Kyle Covington, Joy C. Jayaseelan, Viktoriya Korchina, Lora Lewis, Jianhong Hu, HarshaVardhan Doddapaneni, Donna Muzny, Richard Gibbs, Katherine A. Hoadley, Daniel Hollern, Benjamin G. Vincent, Shengjie Chai, Christof C. Smith, J. Todd Auman, Yan Shi, Shaowu Meng, Tara Skelly, Donghui Tan, Umadevi Veluvolu, Piotr A. Mieczkowski, Corbin D. Jones, Matthew D. Wilkerson, Saianand Balu, Tom Bodenheimer, Alan P. Hoyle, Stuart R. Jefferys, Lisle E. Mose, Janae V. Simons, Matthew G. Soloway, Jeffrey Roach, Joel S. Parker, D. Neil Hayes, Charles M. Perou, Juliann Shih, Andrew D. Cherniack, Matthew Meyerson, Gordon Saksena, Carrie Cibulskis, Steven E. Schumacher, Rameen Beroukhim, Stacey B. Gabriel, Reanne Bowlby, Andrew J. Mungall, Denise Brooks, Katayoon Kasaian, Adrian Ally, Miruna Balasundaram, Rebecca Carlsen, Dorothy Cheung, Eric Chuah, Noreen Dhalla, Robert A. Holt, Steven J.M. Jones, Yussanne Ma, Michael Mayo, Richard A. Moore, A. Gordon Robertson, Jacqueline E. Schein, Payal Sipahimalani, Angela Tam, Nina Thiessen, Tina Wong, Marco A. Marra, Hui Shen, Wanding Zhou, Peter W. Laird, Daniel J. Weisenberger, David J. Van Den Berg, Phillip H. Lai, Mario Berrios, Andrea Holbrook, Moiz S. Bootwalla, Dennis T. Maglinte, Joshua Armenia, Francisco Sánchez-Vega, Nikolaus Schultz, Debyani Chakravarty, Jianjiong Gao, Zachary Heins, Ritika Kundra, Angelica Ochoa, Minwei Liu, Chris Sander, Marc Ladanyi, Vesteinn Thorsson, Amie J. Radenbaugh, Yulia Newton, Joshua M. Stuart, Juok Cho, David I. Heiman, Michael S. Noble, Hailei Zhang, Gad Getz, Nils Gehlenborg, Gordon Saksena, Doug Voet, Pei Lin, Scott Frazer, Jaegil Kim, Michael S. Lawrence, Sam Meier, Timothy Defreitas, Lynda Chin, Apurva M. Hegde, Rehan Akbani, John N. Weinstein, Wenbin Liu, Gordon B. Mills, Yiling Lu, Louise C. Pyle, John Pluta, Katherine L. Nathanson, Satish K. Tickoo, Victor E. Reuter, Rohit Mehra, Leendert Looijenga, Alan H. Bryce, Flavio M. Cárcano, André L. Carvalho, Victoria K. Cortessis, Darren Feldman, Guilherme Godoy, Michael Ittmann, Jeffrey Jones, Tomislav Kulis, Seth Lerner, Davor Lessel, Katherine L. Nathanson, Carl S. Shelley, Daniel O. Vidal, Kristen M. Leraas, Tara M. Lichtenberg, Jay Bowen, Julie M. Gastier-Foster, Mark Gerken, Carmen Helsel, Nilsa C. Ramirez, Lisa Wise, Erik Zmuda, Sandra Cottingham, David Chesla, Charles Saller, Katherine Tarvin, Luiz Fernando Lopes, Cristovam Scapulatempo-Neto, Natália D.A. Aredes, Wolter Oosterhuis, Ad Gillis, Hans Stoop, Wil Eijkenboom, George Sandusky, Sue Ellen Martin, Manju Aron, Siamak Daneshmand, Hooman Djaladat, David Quinn, Tanya Dorff, Jochen K. Lennerz, Leigh B. Thorne, Marija Gamulin, Zeljko Kastelan, Tvrtko Hudolin, Christian Kubisch, Lori Boice, Mei Huang, Amy H. Perou, W. Kimryn Rathmell, Todd Pihl, Yunhu Wan, Qiang Sun, Rashi Naresh, Sudha Chudamani, Jia Liu, Laxmi Lolla, Ye Wu, Martin L. Ferguson, Jean C. Zenklusen, Ina Felau, Jiashan (Julia) Zhang, Margi Sheth, John A. Demchok, Liming Yang, Zhining Wang, Roy Tarnuzzer, Carolyn M. Hutter, Heidi J. Sofia, Tanja M. Davidsen +240 moredoaj +1 more sourceThe present and future of serum diagnostic tests for testicular germ cell tumours. [PDF]
, 2016 Testicular germ cell tumours (GCTs) are the most common malignancy occurring in young adult men and the incidence of these tumours is increasing. Current research priorities in this field include improving overall survival for patients classified as ...A Lorch, AJM Gillis, AJM Gillis, B Trabert, C Ackers, C Fung, C Kollmannsberger, C Kollmannsberger, CA Lago-Hernandez, D Gitlin, D Killock, D Raggi, DC Gilbert, DC Gilbert, DT Schneider, G Belge, G Cohn-Cedermark, G Daugaard, G Daugaard, GW Novotny, H Valadi, HS Haugnes, HS Haugnes, I Nishizono, I Syring, J Vuky, JR Germa, K Fizazi, K Fizazi, K Kobayashi, K Litchfield, KD Miller, KM Grigor, KP Dieckmann, L Rainen, LB Travis, M Bachner, M De Santis, M Spiekermann, M Spiekermann, MA Rijlaarsdam, Matthew J. Murray, ME Blohm, MJ Murray, MJ Murray, MJ Murray, MJ Murray, MJ Murray, MJ Murray, MJ Murray, MP Caby, MR van Dijk, Nicholas Coleman, P Chung, P Warde, PJ Johnson, PM Voorhoeve, R de Wit, R de Wit, R de Wit, R Venkitaraman, RA Huddart, RA Huddart, RA Huddart, RD Palmer, Robert A. Huddart, SA Bustin, SF Hain, T Kawakami, TD Gilligan, TV Tarin, VF Viprey, Z Bing +72 morecore +2 more sources