Results 11 to 20 of about 100,533 (214)
ASN Neuro, 2020 Fifty years have passed since the discovery of glial fibrillary acidic protein (GFAP) by Lawrence Eng and colleagues. Now recognized as a member of the intermediate filament family of proteins, it has become a subject for study in fields as diverse as structural biology, cell biology, gene expression, basic neuroscience, clinical genetics and gene ...
Albee Messing, Michael Brenner
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GFAP-Negative Subcutaneous Sacrococcygeal Extraspinal Ependymoma [PDF]
Case Reports in Dermatology, 2021 Ependymomas are slowly growing glial tumors derived from the ependymal cells and usually occur in the central nervous system (CNS). Ependymomas rarely occur outside of the CNS and they are called extraspinal ependymomas. In spite of their metastatic potential, extraspinal ependymomas can be misdiagnosed for other benign mass like pilonidal cysts.
Kazuya Goto +3 more
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ASN Neuro, 2021 Expression of the GFAP gene has attracted considerable attention because its onset is a marker for astrocyte development, its upregulation is a marker for reactive gliosis, and its predominance in astrocytes provides a tool for their genetic manipulation.
Michael Brenner, Albee Messing
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Hippocampal Astrocyte Response to Melatonin Following Neural Damage Induction in Rats
Basic and Clinical Neuroscience, 2021 Introduction: Brain injury induces an almost immediate response from glial cells, especially astrocytes. Activation of astrocytes leads to the production of inflammatory cytokines and reactive oxygen species that may result in secondary neuronal damage ...
Abdolreza Babaee +5 more
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Increased levels of GFAP and purinergic P2X7 receptor in Alzheimer’s disease brain are associated with Aβ, tau pathologies and synaptic loss [PDF]
Alzheimers Res TherCinzia Maschio +12 more
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Journal of Pain Research, 2021 Marcio Carneiro Vieira,1,2 Fernanda Bezerra de Mello Monte,3 Bruno Eduardo Dematte,3 Tadeu Lima Montagnoli,3 Guilherme Carneiro Montes,3 Jaqueline Soares da Silva,3 Rosalia Mendez-Otero,4 Margarete Manhães Trachez,3 Roberto Takashi Sudo,1,3 Gisele
Vieira M C +9 more
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Increased astrocyte representation in the hippocampus of 5xFAD mice [PDF]
Medicinski Podmladak, 2021 Introduction: Alzheimer's disease is the most common neurodegenerative disorder, characterized by the formation of amyloid plaques and the neurofibrillary tangles in the brain of an ill person, leading to neuronal damage and loss.
Jovanović Violeta +5 more
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Properties of astrocytes cultured from GFAP over-expressing and GFAP mutant mice [PDF]
Experimental Cell Research, 2009 Alexander disease is a fatal leukoencephalopathy caused by dominantly-acting coding mutations in GFAP. Previous work has also implicated elevations in absolute levels of GFAP as central to the pathogenesis of the disease. However, identification of the critical astrocyte functions that are compromised by mis-expression of GFAP has not yet been possible.
Woosung, Cho, Albee, Messing
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Role of Aldynoglia Cells in Neuroinflammatory and Neuroimmune Responses after Spinal Cord Injury
Cells, 2021 Aldynoglia are growth-promoting cells with a morphology similar to radial glia and share properties and markers with astrocytes and Schwann cells. They are distributed in several locations throughout the adult central nervous system, where the cells of ...
Vinnitsa Buzoianu-Anguiano +2 more
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Brain Pathology, 1994 One of the most remarkable characteristics of astrocytes is their vigorous response to diverse neurologic insults, a feature that is well conserved across a variety of different species. The astroglial response occurs rapidly and can be detected within one hour of a focal mechanical trauma (Mucke et al., 1991).
L F, Eng, R S, Ghirnikar
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