Results 11 to 20 of about 194,651 (386)
ASN Neuro, 2021 Expression of the GFAP gene has attracted considerable attention because its onset is a marker for astrocyte development, its upregulation is a marker for reactive gliosis, and its predominance in astrocytes provides a tool for their genetic manipulation.
Albee Messing
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Glial Fibrillary Acidic Protein (GFAP): Neuroinflammation Biomarker in Acute Ischemic Stroke
Journal of Inflammation Research, 2021 Lisda Amalia Department of Neurology, The First Affiliated Hospital of Faculty of Medicine, Universitas Padjadjaran/RSUP dr. Hasan Sadikin, Bandung, IndonesiaCorrespondence: Lisda Amalia Jl.Pasteur 38, Bandung, 40161, IndonesiaEmail dr.lisda@gmail ...
Lisda Amalia
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GFAP as a Potential Biomarker for Alzheimer’s Disease: A Systematic Review and Meta-Analysis
Cells, 2023 Blood biomarkers have been considered tools for the diagnosis, prognosis, and monitoring of Alzheimer’s disease (AD). Although amyloid-β peptide (Aβ) and tau are primarily blood biomarkers, recent studies have identified other reliable candidates that ...
Ka Young Kim, Keun-A Chang
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Plasma GFAP is an early marker of amyloid-β but not tau pathology in Alzheimer’s disease
Brain, 2021 Although recent clinical trials targeting amyloid-β in Alzheimer’s disease have shown promising results, there is increasing evidence suggesting that understanding alternative disease pathways that interact with amyloid-β metabolism and amyloid pathology
Joana B Pereira +2 more
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ASN Neuro, 2020 Fifty years have passed since the discovery of glial fibrillary acidic protein (GFAP) by Lawrence Eng and colleagues. Now recognized as a member of the intermediate filament family of proteins, it has become a subject for study in fields as diverse as ...
A. Messing, M. Brenner
semanticscholar +4 more sources
Proceedings of the National Academy of Sciences of the United States of America, 2021 Significance This study reports that the intermediate filament protein GFAP is modified with protein palmitoylation. Increased GFAP expression and palmitoylation is involved in astrocyte proliferation and astrogliosis.
Liaoxun Lu, Muding Rao, Tianzhu Chao
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Immunohistochemical analysis of GFAP expression in the experimental sepsis-associated encephalopathy
Patologìâ, 2021 Pathophysiology of sepsis-associated encephalopathy (SAE) is linked to blood-brain barrier breakdown, neuroinflammation and neurotransmitter imbalance in the brain. Astroglia, the most abundant cell population within the brain, plays the critical role in
T. V. Shulyatnikova, V. O. Tumaskyi
doaj +3 more sources
Blood GFAP as an emerging biomarker in brain and spinal cord disorders
Nature Reviews Neurology, 2022 Ahmed Abdelhak +2 more
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Redox Biology, 2022 Alexander disease is a fatal neurological disorder caused by mutations in the intermediate filament protein Glial Fibrillary Acidic Protein (GFAP), which is key for astrocyte homeostasis.
Dolores Perez-Sala
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The GFAP proteoform puzzle: How to advance GFAP as a fluid biomarker in neurological diseases
Journal of NeurochemistryGlial fibrillary acidic protein (GFAP) is a well‐established biomarker of reactive astrogliosis in the central nervous system because of its elevated levels following brain injury and various neurological disorders.
Dea Gogishvili +6 more
semanticscholar +6 more sources