Results 31 to 40 of about 194,651 (386)

Prospective evaluation of GFAP point-of-care testing for rapid diagnosis of glioblastoma. [PDF]

J Neurooncol
Blums K, Kalra LP, Nerntengian N, Zylyftari S, Luger S, Wehinger J, Bos D, Barthelmes S, Sakowitz O, Meckel S, Baum H, Ulmer M, Foerch C.   +12 more
europepmc   +2 more sources

Diagnostic value of plasma p-tau181, NfL, and GFAP in a clinical setting cohort of prevalent neurodegenerative dementias

Alzheimer's Research & Therapy, 2022
Background Increasing evidence supports the use of plasma biomarkers of neurodegeneration and neuroinflammation to screen and diagnose patients with dementia.
Simone Baiardi, C. Quadalti, A. Mammana, Sofia Dellavalle, C. Zenesini, L. Sambati, R. Pantieri, Barbara Polischi, Luciano Romano, Matteo Suffritti, G. Bentivenga, V. Randi, M. Stanzani-Maserati, S. Capellari, Piero Parchi   +14 more
semanticscholar   +1 more source

Prognostic value of day-of-injury plasma GFAP and UCH-L1 concentrations for predicting functional recovery after traumatic brain injury in patients from the US TRACK-TBI cohort: an observational cohort study.

Lancet Neurology, 2022
BACKGROUND The prognostic value of glial fibrillary acidic protein (GFAP) and ubiquitin C-terminal hydrolase L1 (UCH-L1) as day-of-injury predictors of functional outcome after traumatic brain injury is not well understood.
F. Korley, Sonia Jain, Xiaoying Sun, A. Puccio, J. Yue, Raquel C Gardner, Kevin K. W. Wang, D. Okonkwo, E. Yuh, P. Mukherjee, L. Nelson, Sabrina R. Taylor, A. Markowitz, R. Diaz-Arrastia, G. Manley, O. Adeoye, Neeraj Badatjia, A. Duhaime, Adam R Ferguson, B. Foreman, J. Giacino, S. Gopinath, R. Grandhi, Ryan S. Kitagawa, C. Madden, R. Merchant, M. McCrea, Laura B. Ngwenya, Miri Rabinowitz, C. Robertson, David M Schnyer, Murray B. Stein, M. Vassar, Vincent Y. Wang, A. Valadka, R. Zafonte   +35 more
semanticscholar   +1 more source

GFAP-Negative Subcutaneous Sacrococcygeal Extraspinal Ependymoma [PDF]

Case Reports in Dermatology, 2021
Ependymomas are slowly growing glial tumors derived from the ependymal cells and usually occur in the central nervous system (CNS). Ependymomas rarely occur outside of the CNS and they are called extraspinal ependymomas. In spite of their metastatic potential, extraspinal ependymomas can be misdiagnosed for other benign mass like pilonidal cysts.
Kazuya Goto, Hiroko Fujii, Gen Honjo, Satoshi Kore-eda   +3 more
openaire   +3 more sources

Plasma GFAP in Parkinson’s disease with cognitive impairment and its potential to predict conversion to dementia

npj Parkinson's Disease, 2023
Glial fibrillary acidic protein (GFAP) has been suggested as a biomarker for reactive astrogliosis. We measured the levels of plasma GFAP by Simoa in 60 patients with PD with normal cognition, 63 with mild cognitive impairment (PD-MCI), 24 with dementia (
Yilin Tang, Linlin Han, Shiyu Li, Tianyu Hu, Zhiheng Xu, Yun Fan, Xiaoniu Liang, Huan Yu, Jianjun Wu, Jian Wang   +9 more
semanticscholar   +1 more source

Association of plasma glial fibrillary acidic protein (GFAP) with neuroimaging of Alzheimer's disease and vascular pathology

Alzheimer's & Dementia, 2022
Introduction: Plasma glial fibrillary acidic protein (GFAP) may be associated with amyloid burden, neurodegeneration, and stroke but its specificity for Alzheimer's disease (AD) in the general population is unclear.
D. Shir, J. Graff‐Radford, Ekaterina I. Hofrenning, T. Lesnick, S. Przybelski, V. Lowe, D. Knopman, R. Petersen, C. Jack, P. Vemuri, A. Algeciras-Schimnich, M. Campbell, N. Stricker, M. Mielke   +13 more
semanticscholar   +1 more source

A Single Dose of Atorvastatin Applied Acutely after Spinal Cord Injury Suppresses Inflammation, Apoptosis, and Promotes Axon Outgrowth, Which Might Be Essential for Favorable Functional Outcome. [PDF]

, 2018
The aim of our study was to limit the inflammatory response after a spinal cord injury (SCI) using Atorvastatin (ATR), a potent inhibitor of cholesterol biosynthesis.
Bacova, Maria, Bimbova, Katarina, Fedorova, Jana, Galik, Jan, Jachova, Jana, Kisucka, Alexandra, Lukacova, Nadezda, Marsala, Martin, Papcunova, Stefania, Pavel, Jaroslav, Stropkovska, Andrea, Zavacky, Peter   +11 more
core   +2 more sources

Time course and diagnostic utility of NfL, tau, GFAP, and UCH-L1 in subacute and chronic TBI

Neurology, 2020
Objective To determine whether neurofilament light (NfL), glial fibrillary acidic protein (GFAP), tau, and ubiquitin C-terminal hydrolase-L1 (UCH-L1) measured in serum relate to traumatic brain injury (TBI) diagnosis, injury severity, brain volume, and ...
P. Shahim, Adam M. Politis, Andre J. van der Merwe, Brian Moore, V. Ekanayake, S. Lippa, Y. Chou, D. Pham, J. Butman, R. Diaz-Arrastia, H. Zetterberg, K. Blennow, J. Gill, D. Brody, L. Chan   +14 more
semanticscholar   +1 more source

Hippocampal Astrocyte Response to Melatonin Following Neural Damage Induction in Rats

Basic and Clinical Neuroscience, 2021
Introduction: Brain injury induces an almost immediate response from glial cells, especially astrocytes. Activation of astrocytes leads to the production of inflammatory cytokines and reactive oxygen species that may result in secondary neuronal damage ...
Abdolreza Babaee, Seyed Hassan Eftekhar Vaghefi, Samereh Dehghani Soltani, Majid Asadi Shekaari, Nader Shahrokhi, Mohsen Basiri   +5 more
doaj  

Astrogliosis and episodic memory in late life: higher GFAP is related to worse memory and white matter microstructure in healthy aging and Alzheimer's disease.

Neurobiology of Aging, 2021
Astrocytes play a formative role in memory consolidation during physiological conditions; when dysregulated, astrocytes release glial fibrillary acidic protein (GFAP), which has been linked with negative memory outcomes in animal studies. We examined the
B. Bettcher, Kaitlin E. Olson, Nichole E. Carlson, Brice V. McConnell, Timothy D. Boyd, Vanesa Adame, D. Solano, Paige Anton, N. Markham, A. Thaker, Alexandria M. Jensen, Erika N. Dallmann, H. Potter, C. Coughlan   +13 more
semanticscholar   +1 more source