Results 51 to 60 of about 17,618 (160)

Association of GHR Polymorphisms with Milk Production in Buffaloes [PDF]

Animals, 2020
For its role in the mediation of growth hormone (GH) galactopoietic effect, growth hormone receptor (GHR) was considered a functional candidate gene for milk performance in cattle. However, its genetic variation and potential effect have not been investigated in Egyptian buffaloes.
Shymaa M. El-Komy, Ayman A. Saleh, Tamer M. Abdel-Hamid, Mohammed A. El-Magd   +3 more
openaire   +3 more sources

Marfan Syndrome Associated With Intellectual Disability and Behavioral Anomalies: Further Evidence for the Effect of Compound Heterozygous Variants in FBN1 on Phenotypic Severity

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Marfan syndrome (MFS) is a rare connective tissue disorder characterized by involvement of the cardiovascular, ocular, and musculoskeletal systems. Pathogenic variants in FBN1 cause most of the MFS cases; however, intellectual disability (ID) is rarely observed. A non‐consanguineous Pakistani family with four affected individuals was recruited.
Azmatullah Khan, Naseebullah Kakar, Ainullah Kakar, Malte Spielmann, Sajid Malik   +4 more
wiley   +1 more source

Host–microbiota interaction drives 5‐hydroxyindole‐3‐acetic acid production to promote linear growth in infant mice

iMetaOmics, EarlyView.
This study discovered that Lactiplantibacillus plantarum Hi188 promoted linear growth in postweaning mice. Transcriptomic analysis, untargeted metabolomics, and in vitro experiments showed that the elevated levels of 5‐hydroxyindole‐3‐acetic acid (5‐HIAA) activated the hepatic aryl hydrocarbon receptor (AhR) and subsequently promoted insulin‐like ...
Yongmei Yang, Jing Yang, Weiyao Zhang, Linghao Zhou, Chenxu Zhu, Xuguang Zhang, Yuejian Mao, Meiling Zhang   +7 more
wiley   +1 more source

Interaction of growth hormone receptor/binding protein gene disruption and caloric restriction for insulin sensitivity and attenuated aging [v2; ref status: indexed, http://f1000r.es/5a7]

F1000Research, 2015
The correlation of physiological sensitivity to insulin (vis-à-vis glycemic regulation) and longevity is extensively established, creating a justifiable gerontological interest on whether insulin sensitivity is causative, or even predictive, of some or ...
Oge Arum, Jamal Saleh, Ravneet Boparai, Jeremy Turner, John Kopchick, Romesh Khardori, Andrzej Bartke   +6 more
doaj   +1 more source

Identification of the cDNA Encoding the Growth Hormone Receptor (GHR) and the Regulation of GHR and IGF-I Gene Expression by Nutritional Status in Reeves’ Turtle (Chinemys reevesii)

Frontiers in Genetics, 2020
Chinemys reevesii (Reeves’ turtle) is a slow-growing reptile that is distributed widely across China. Prior to this study, the cDNA sequence of the growth hormone receptor (GHR) in the Reeve’s turtle, or how periods of starvation might influence the gene
Wenlu Zhu, Yuhui He, Zhuohao Ruan, Zhuohao Ruan, Xiquan Zhang, Liangyuan Liao, Yicong Gao, Nani Lin, Xiancan Chen, Rui Liang, Wen-sheng Liu, Wen-sheng Liu   +11 more
doaj   +1 more source

Intact pulse cotyledon cell diet improves systemic growth via the somatotropic axis in malnourished mice

iMetaOmics, EarlyView.
The MAL‐IC diet promotes growth in malnourished mice by regulating the gut microbiota—increasing the abundance of carbohydrate‐utilizing bacteria and SCFAs production. SCFAs circulate to the liver via the gut–liver axis, where they bind FFAR2 and activate the somatotropic axis, thereby stimulating GHR‐mediated GH signaling and increasing IGF‐1 and ...
Yumeng Yan, Zhuqing Xie, Zhipeng Gu, Zhongxin Li, Qiang Huang, Bin Zhang   +5 more
wiley   +1 more source

Correlation between gallstones and fasting blood glucose to serum high-density lipoprotein cholesterol ratio among American adults

Frontiers in Medicine
BackgroundResearch indicates that the ratio of fasting blood glucose (FBG) to serum high-density lipoprotein cholesterol (HDL-C) (GHR) can accurately predict many diseases.
Bo Wu, Huachao Zheng, Caixiang Zhuang, Jiesheng Mao, Luo Yuncheng, Lidong Huang, Min Li, Zhao Feiyang, Sisi Lin, Pengwei Wang, Yiren Hu   +10 more
doaj   +1 more source

PTQ10‐based organic photodetectors for visible light detection and their tolerance to impurities

Polymer International, EarlyView.
PTQ10‐based organic photodetectors were found to be very sensitive to the presence of Pd(PPh3)4 catalyst traces, impacting the transport properties and light detection capacities. Abstract PTQ10 donor polymer has attracted a lot of interest in organic optoelectronics, particularly in the field of organic photovoltaics, owing to its ease of synthesis ...
Chloé Dindault, Gilles Henri Roche, Martial Leyney, Tanguy Jousselin‐Oba, Laurence Vignau, Sylvain Chambon, Pierre‐Antoine Bonnardel, Sébastien Taillemite, Guillaume Wantz, Lionel Hirsch   +9 more
wiley   +1 more source

Blockade of growth hormone receptor signaling by using pegvisomant: A functional therapeutic strategy in hepatocellular carcinoma

Frontiers in Oncology, 2022
Hepatocellular carcinoma (HCC) is an aggressive neoplasm with poor clinical outcome because most patients present at an advanced stage, at which point curative surgical options, such as tumor excision or liver transplantation, are not feasible. Therefore,
Ahmed O. Kaseb, Abedul Haque, Deeksha Vishwamitra, Manal M. Hassan, Lianchun Xiao, Bhawana George, Vishal Sahu, Yehia I. Mohamed, Roberto Carmagnani Pestana, Jamie Lynne Lombardo, Rony Avritscher, James C. Yao, Robert A. Wolff, Asif Rashid, Jeffrey S. Morris, Hesham M. Amin, Hesham M. Amin   +16 more
doaj   +1 more source

Quaternion Derivatives: The GHR Calculus

, 2014
Quaternion derivatives in the mathematical literature are typically defined only for analytic (regular) functions. However, in engineering problems, functions of interest are often real-valued and thus not analytic, such as the standard cost function. The HR calculus is a convenient way to calculate formal derivatives of both analytic and non-analytic ...
Xu, Dongpo, Jahanchahi, Cyrus, Took, Clive C., Mandic, Danilo P.   +3 more
openaire   +2 more sources