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Functional Study of PgHDZ01 Gene Involved in the Regulation of Ginsenoside Biosynthesis in Panax ginseng [PDF]

Plants
The HD-Zip gene family plays a vital regulatory role in plant growth and development, but its function in plant secondary metabolism remains to be further elucidated.
Chaofan Wang, Xin Cheng, Li Li, Ruicen Liu, Dinghui Wang, Yue Jiang, Yanfang Wang, Kangyu Wang, Mingzhu Zhao, Yi Wang, Meiping Zhang   +10 more
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Does ginsenoside Rg1 promote intervertebral disc repair? An experimental study insights into ferroptosis mechanism [PDF]

Journal of Translational Medicine
Background Intervertebral disc degeneration (IVDD) is a complex and multifactorial condition characterized by the progressive deterioration of the intervertebral discs.
Dongliang Gong, Feiyun Xia, Fuyong Wang, Xiaoxia Tong, Qing Yang, Kelv Shen, Baihan Sun, Nong Chen, Zhengfeng Lu   +8 more
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Ginsenoside CK, rather than Rb1, possesses potential chemopreventive activities in human gastric cancer via regulating PI3K/AKT/NF-κB signal pathway

Frontiers in Pharmacology, 2022
Ginsenoside Rb1, a main component of ginseng, is often transformed into ginsenoside CK by intestinal flora to exert various pharmacological activity. However, it remains unclear whether ginsenoside CK is responsible for the anti-gastric cancer effect of ...
Yan Wan, Dong Liu, Jia Xia, Jin-Feng Xu, Li Zhang, Yu Yang, Jiao-Jiao Wu, Hui Ao, Hui Ao   +8 more
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Ginsenoside Rg3 inhibits the malignant progression of cervical cancer cell by regulating AKT2 expression

Heliyon, 2023
Although ginsenoside Rg3 has been shown to exert anticancer effects in various malignancies, the effects and molecular mechanisms of ginsenoside Rg3 in cervical cancer (CC) remain unclear.
Hui Liu, Tingting Xie, Yuan Liu
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Ginsenoside Rd attenuated hyperglycemia via Akt pathway and modulated gut microbiota in streptozotocin-induced diabetic rats

Current Research in Food Science, 2023
Ginsenoside Rd is a protopanaxadiol abundant in Panax ginseng and Panax notoginseng. It has been reported that ginsenoside Rd possesses various health benefits, such as anti-diabetic, anti-tumor and anti-inflammatory.
Wei Wang, Fengtao Guan, Gianni Sagratini, Jie Yan, Jiahan Xie, Zhibo Jin, Meihong Liu, Huimin Liu, Jingsheng Liu   +8 more
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Advances in Ginsenosides [PDF]

Biomolecules, 2020
Ginsenosides are unique to plants that belong to the Panax genus [...]
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The osteogenesis of Ginsenoside Rb1 incorporated silk/micro-nano hydroxyapatite/sodium alginate composite scaffolds for calvarial defect

International Journal of Oral Science, 2022
Ginsenoside Rb1, the effective constituent of ginseng, has been demonstrated to play favorable roles in improving the immunity system. However, there is little study on the osteogenesis and angiogenesis effect of Ginsenoside Rb1.
Yuqiong Wu, Jiahui Du, Qianju Wu, Ao Zheng, Lingyan Cao, Xinquan Jiang   +5 more
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Effects of Minor Ginsenosides, Ginsenoside Metabolites, and Ginsenoside Epimers on the Growth of Caenorhabditis elegans [PDF]

Journal of Ginseng Research, 2011
In the previous report, we have demonstrated that ginsenoside Rc, one of major ginsenosides, is a major component for the restoration for normal growth of worms in cholesterol-deprived medium. In the present study, we further investigated the roles of minor ginsenosides, such as ginsenoside Rh1 and Rh2, ginsenoside metabolites such as compound K (CK ...
Lee, Joon-Hee, Ahn, Ji-Yun, Shin, Tae-Joon, Choi, Sun-Hye, Lee, Byung-Hwan, Hwang, Sung-Hee, Kang, Jiyeon, Kim, Hyeon-Joong, Park, Chan-Woo, Nah, Seung-Yeol   +9 more
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Evaluation of glucosidases of Aspergillus niger strain comparing with other glucosidases in transformation of ginsenoside Rb1 to ginsenosides Rg3

Journal of Ginseng Research, 2014
The transformation of ginsenoside Rb1 into a specific minor ginsenoside using Aspergillus niger KCCM 11239, as well as the identification of the transformed products and the pathway via thin layer chromatography and high performance liquid chromatography
Kyung Hoon Chang, Mi Na Jo, Kee-Tae Kim, Hyun-Dong Paik   +3 more
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Transcriptome-Wide Analysis for Ginsenoside Rb3 Synthesis-Related Genes and Study on the Expression of Methyl Jasmonate Treatment in Panax ginseng

Life, 2021
Panax ginseng C. A. Meyer is a kind of renascent herb that belongs to the genus Panax in the family Araliaceae. It is a traditional Chinese precious herbal medicine with a long history of medicinal use.
Kangyu Wang, Zixuan Zhang, Shaokun Li, Jian Hu, Tao Liu, Yang Jiang, Jun Wu, Minghai Lu, Mingzhu Zhao, Li Li, Lei Zhu, Yanfang Wang, Yi Wang, Meiping Zhang   +13 more
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