Results 11 to 20 of about 8,127 (213)

Progress in the Conversion of Ginsenoside Rb1 into Minor Ginsenosides Using β-Glucosidases

Foods, 2023
In recent years, minor ginsenosides have received increasing attention due to their outstanding biological activities, yet they are of extremely low content in wild ginseng.
Hongrong Zhu, Rui Zhang, Zunxi Huang, Junpei Zhou   +3 more
doaj   +3 more sources

Enzymatic formation of compound-K from ginsenoside Rb1 by enzyme preparation from cultured mycelia of Armillaria mellea

Journal of Ginseng Research, 2016
Background: Minor saponins or human intestinal bacterial metabolites, such as ginsenosides Rg3, F2, Rh2, and compound K, are more pharmacologically active than major saponins, such as ginsenosides Rb1, Rb2, and Rc.
Jitendra Upadhyaya, Min-Ji Kim, Young-Hoi Kim, Sung-Ryong Ko, Hee-Won Park, Myung-Kon Kim   +5 more
doaj   +3 more sources

Neuroprotective Mechanisms of Ginsenoside Rb1 in Central Nervous System Diseases

Frontiers in Pharmacology, 2022
Panax ginseng and Panax notoginseng, two well-known herbs with enormous medical value in Asian countries, have a long usage history in China for the therapy of some diseases, such as stroke.
Liang Gong, Jiayi Yin, Yu Zhang, Ren Huang, Yuxuan Lou, Haojie Jiang, Liyan Sun, Jinjing Jia, Xiansi Zeng   +8 more
doaj   +3 more sources

Ginsenoside Rb1 improves cardiac function and remodeling in heart failure

Experimental Animals, 2017
We investigated the effect of ginsenoside Rb1 on cardiac function and remodeling in heart failure (HF). Four weeks after HF induction, the rats were administrated with ginsenoside Rb1 (35 and 70 mg/kg) and losartan (4.5 mg/kg) for 8 weeks. Losartan was used as a positive control.
Zheng, Xian, Wang, Shuai, Zou, Xiaoming, Jing, Yating, Yang, Ronglai, Li, Siqi, Wang, Fengrong   +6 more
openaire   +5 more sources

Kinetic study for the optimization of ginsenoside Rg3 production by heat treatment of ginsenoside Rb1

Journal of Ginseng Research, 2015
Background: Ginsenoside Rg3 is a promising anticancer agent. It is usually produced by heat treatment of ginseng, in which ginsenoside Rb1 is the major ginsenoside.
Hoang Tung Vo, Jae Youl Cho, Yong-Eui Choi, Yong-Soon Choi, Yeon-Ho Jeong   +4 more
doaj   +3 more sources

Ginsenoside Rb1 as an Anti-Diabetic Agent and Its Underlying Mechanism Analysis

Cells, 2019
Panax ginseng and Panax notoginseng, two well-known medical plants with economic value, have a long history of use for managing various diseases in Asian countries.
Ping Zhou, Weijie Xie, Shuaibing He, Yifan Sun, Xiangbao Meng, Guibo Sun, Xiaobo Sun   +6 more
doaj   +3 more sources

Progress of Ginsenoside Rb1 in neurological disorders. [PDF]

Front Pharmacol
Ginseng is frequently used in traditional Chinese medicine to treat neurological disorders. The primary active component of ginseng is ginsenoside, which has been classified into more than 110 types based on their chemical structures. Ginsenoside Rb1 (GsRb1)—a protopanaxadiol saponin and a typical ginseng component—exhibits anti-inflammatory, anti ...
Ling G, Zhang M, Chen C, Wang Y, Gao Q, Li J, Yuan H, Jin W, Lin W, Yang L.   +9 more
europepmc   +4 more sources

Myostain is involved in ginsenoside Rb1-mediated anti-obesity. [PDF]

Pharm Biol, 2022
Obesity, one of the major public health problems worldwide, has attracted increasing attention. Ginsenoside Rb1 is the most abundant active component of Panax ginseng C.A.Mey (Araliaceae) and is reported to have beneficial effects on obesity and diabetes. However, the mechanisms by which Rb1 regulates obesity remain to be explored.This paper intends to
Li HS, Kuang JY, Liu GJ, Wu WJ, Yin XL, Li HD, Wang L, Qin T, Zhang WC, Sun YY.   +9 more
europepmc   +4 more sources

Intestinal Lactobacillus species improve immune enhancement by ginsenoside Rb1 and ginsenoside Rb1 increases intestinal Akkermansia proportions

Journal of Functional Foods, 2021
This study aimed to identify correlations between the immune enhancement effects of ginsenoside Rb1 (G-Rb1) and the composition of the gut microbiota in mice. Feces samples collected from mice with high (HI) and low (LI) immune enhancement before and after the feeding of a diet supplemented with G-Rb1 were assessed via metagenomic analysis.
Miseon Sung, Yohan Yoon, Jeeyeon Lee
openaire   +2 more sources

Ginsenoside Rb1 Attenuates Triptolide-Induced Cytotoxicity in HL-7702 Cells via the Activation of Keap1/Nrf2/ARE Pathway

Frontiers in Pharmacology, 2022
Triptolide (TP) is the major bioactive compound extracted from Tripterygium wilfordii Hook F. It exerts anti-inflammatory, antirheumatic, antineoplastic, and neuroprotective effects.
Hulinyue Peng, Longtai You, Chunjing Yang, Kaixin Wang, Manting Liu, Dongge Yin, Yuchen Xu, Xiaoxv Dong, Xingbin Yin, Jian Ni   +9 more
doaj   +1 more source