Results 11 to 20 of about 5,735 (170)

Progress of Ginsenoside Rb1 in neurological disorders [PDF]

open access: yesFrontiers in Pharmacology
Ginseng is frequently used in traditional Chinese medicine to treat neurological disorders. The primary active component of ginseng is ginsenoside, which has been classified into more than 110 types based on their chemical structures. Ginsenoside Rb1 (GsRb1)—a protopanaxadiol saponin and a typical ginseng component—exhibits anti-inflammatory, anti ...
Wenwen Jin, Gao Qiqi, Jin Wenwen
exaly   +5 more sources

Kinetic study for the optimization of ginsenoside Rg3 production by heat treatment of ginsenoside Rb1

open access: yesJournal of Ginseng Research, 2015
Background: Ginsenoside Rg3 is a promising anticancer agent. It is usually produced by heat treatment of ginseng, in which ginsenoside Rb1 is the major ginsenoside.
Hoang Tung Vo   +4 more
doaj   +3 more sources

Neuroprotective Mechanisms of Ginsenoside Rb1 in Central Nervous System Diseases

open access: yesFrontiers in Pharmacology, 2022
Panax ginseng and Panax notoginseng, two well-known herbs with enormous medical value in Asian countries, have a long usage history in China for the therapy of some diseases, such as stroke.
Liang Gong   +8 more
doaj   +3 more sources

Ginsenoside Rb1 Attenuates Triptolide-Induced Cytotoxicity in HL-7702 Cells via the Activation of Keap1/Nrf2/ARE Pathway

open access: yesFrontiers in Pharmacology, 2022
Triptolide (TP) is the major bioactive compound extracted from Tripterygium wilfordii Hook F. It exerts anti-inflammatory, antirheumatic, antineoplastic, and neuroprotective effects.
Hulinyue Peng   +9 more
doaj   +1 more source

Antiobesity and Antihyperglycemic Effects of Ginsenoside Rb1 in Rats [PDF]

open access: yesDiabetes, 2010
OBJECTIVE Obesity and type 2 diabetes are national and worldwide epidemics. Because currently available antiobesity and antidiabetic drugs have limited efficacy and/or safety concerns, identifying new medicinal agents, such as ginsenoside Rb1 (Rb1) as reported here, offers exciting possibilities for future ...
Xiong, Ye   +7 more
openaire   +2 more sources

Anxiolytic and Antidepressant Activities of Ginsenoside Rb1 [PDF]

open access: yesBiomolecules and Therapeutics, 2007
The psychopharmacological profile of ginsenosides has not yet been confirmed systematically although various neuropharmacological activities associated with them have been investigated. In the present study, the psychological activities of Rb1 were investigated to evaluate whether it can be used in treatment or prevention of psychological disorders ...
Jong-Hyun Choi   +9 more
openaire   +1 more source

Comprehensive multiomics analysis of the effect of ginsenoside Rb1 on hyperlipidemia

open access: yesAging, 2021
We analyzed the effects of ginsenoside Rb1 on hyperlipidemic in model mice. Using stool, plasma and hepatic tissue samples, we observed that the genera Blautia and Allobaculum were increased and Turicibacter was decrease in Rb1-treated mice as compared to untreated model mice.
Lianqun, Jia   +12 more
openaire   +2 more sources

Ginsenoside Rb1 attenuates diabetic retinopathy in streptozotocin-induced diabetic rats [PDF]

open access: yesActa Cirúrgica Brasileira, 2019
Purpose: To investigated the effects of ginsenoside Rb1 on diabetic retinopathy in streptozotocin-induced diabetic rats. Methods: Diabetes was induced by a single intraperitoneal injection of streptozotocin (80 mg/kg) in male Wistar rats.
Changxia Dong   +5 more
doaj   +1 more source

Ginsenoside Rb1 Alleviated the AKI to CKD Transition by Targeting VEGFR2. [PDF]

open access: yesJ Cell Mol Med
ABSTRACTThe decrease of peritubular capillaries, a pathological feature of acute kidney injury (AKI), is a critical part that promotes the transition of AKI to chronic kidney disease (CKD). Ginsenoside Rb1 (Rb1) has various pharmacological effects on multiple systemic diseases.
Zhang K   +9 more
europepmc   +3 more sources

Identification of β-Glucosidase Activity of Lentilactobacillus buchneri URN103L and Its Potential to Convert Ginsenoside Rb1 from Panax ginseng

open access: yesFoods, 2022
Lentilactobacillus buchneri isolated from Korean fermented plant foods produces β-glucosidase, which can hydrolyze ginsenoside Rb1 from Panax ginseng to yield ginsenoside Rd.
Gereltuya Renchinkhand   +4 more
doaj   +1 more source

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