Results 21 to 30 of about 5,735 (170)
Myostain is involved in ginsenoside Rb1-mediated anti-obesity
Pharmaceutical Biology, 2022 Obesity, one of the major public health problems worldwide, has attracted increasing attention. Ginsenoside Rb1 is the most abundant active component of Panax ginseng C.A.Mey (Araliaceae) and is reported to have beneficial effects on obesity and diabetes. However, the mechanisms by which Rb1 regulates obesity remain to be explored.This paper intends to
Hong-Shi Li +9 more
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Ginsenoside Rb1 as a neuroprotective agent: A review
Brain Research Bulletin, 2016 Ginsenosides represent the major bioactive components of ginseng. These triterpenoid saponins have been shown to exert numerous beneficial effects on the human body. Recent evidences suggest that ginsenosides may be useful for the management and treatment of several diseases of the central nervous system (CNS).
Touqeer, Ahmed +7 more
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The Melanogenesis-Inhibitory Effect and the Percutaneous Formulation of Ginsenoside Rb1 [PDF]
AAPS PharmSciTech, 2014 Ginsenoside Rb1 (Rb1) is the most predominant ginsenoside isolated from the roots of ginseng (Panax ginseng C. A. Meyer). This compound is active in various human biological pathways that are involved in human collagen synthesis and inhibition of cell apoptosis.
Lin, Wang +10 more
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International Journal of Polymer Science, 2020 This article reports the effect of ginsenoside Rb1 on some properties, morphology, and the drug release process of the chitosan (CS)/alginate (AG)/lovastatin (LOV) composite films prepared by a solution method using different contents of ginsenoside Rb1.
Thi-Loc Thach +7 more
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Protective Effects of Ginsenoside Rb1 in Rats with Diabetic Cardiomyopathy
Indian Journal of Pharmaceutical Sciences, 2022 Objective: Ginsenosides play an important role in the treatment of diabetes and obesity. Our group predicted that ginsenoside Rb1 combined with insulin would have a protective effect in diabetic cardiomyopathy (DCM). Method: A diabetic model was induced in eight-week-old male Sprague-Dawley rats with a single intraperitoneal injection of 70 mg / kg ...
Zhang, Fen, Dong, Yang, Wu, Jie
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Ginsenoside Rb1 Protects Against Diabetic Cardiomyopathy by Regulating the Adipocytokine Pathway
Journal of Inflammation Research, 2022 Chenyang Zhang,1 Meixin Han,2 Xuelian Zhang,1 Hongna Tong,1 Xiaobo Sun,1 Guibo Sun1 1Institute of Medicinal Plant Development, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, People’s Republic of China; 2College of Pharmacy,
Zhang C +5 more
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Journal of Ginseng Research, 2021 Background: Gut microbiota mainly function in the biotransformation of primary ginsenosides into bioactive metabolites. Herein, we investigated the effects of three prebiotic fibers by targeting gut microbiota on the metabolism of ginsenoside Rb1 in vivo.
Xiaoyan Zhang +9 more
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The effects of ginsenoside Rb1 on JNK in oxidative injury in cardiomyocytes [PDF]
Archives of Pharmacal Research, 2012 Reactive oxygen species (ROS) can induce oxidative injury via iron interactions (i.e. Fenton chemistry and hydroxyl radical formation). Our prior work suggested that American ginseng berry extract and ginsenoside Re were highly cardioprotective against oxidant stress.
Jing, Li +10 more
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Food Science of Animal Resources, 2017 This study was conducted to isolate and characterize Paenibacillus sp. MBT213 possessing β-glucosidase activity from raw milk, and examine the enzymatic capacity on the hydrolysis of a major ginsenoside (Rb1).
Gereltuya Renchinkhand +7 more
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Neural Regeneration Research, 2019 Accumulating studies suggest that neuroinflammation characterized by microglial overactivation plays a pivotal role in the pathogenesis of Parkinson’s disease.
Da-Wei Li +6 more
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