Results 21 to 30 of about 5,968 (172)

Ginsenoside Rb1 improves energy metabolism after spinal cord injury

open access: yesNeural Regeneration Research, 2023
Mitochondrial damage caused by oxidative stress and energy deficiency induced by focal ischemia and hypoxia are important factors that aggravate diseases. Studies have shown that ginsenoside Rb1 has neurotrophic and neuroprotective effects.
Shan Wen   +6 more
doaj   +1 more source

Myostain is involved in ginsenoside Rb1-mediated anti-obesity

open access: yesPharmaceutical Biology, 2022
Obesity, one of the major public health problems worldwide, has attracted increasing attention. Ginsenoside Rb1 is the most abundant active component of Panax ginseng C.A.Mey (Araliaceae) and is reported to have beneficial effects on obesity and diabetes. However, the mechanisms by which Rb1 regulates obesity remain to be explored.This paper intends to
Hong-Shi Li   +9 more
openaire   +3 more sources

Assessment of the Role of Ginsenoside RB1 Active Substance in Alginate/Chitosan/Lovastatin Composite Films

open access: yesInternational Journal of Polymer Science, 2020
This article reports the effect of ginsenoside Rb1 on some properties, morphology, and the drug release process of the chitosan (CS)/alginate (AG)/lovastatin (LOV) composite films prepared by a solution method using different contents of ginsenoside Rb1.
Thi-Loc Thach   +7 more
doaj   +1 more source

The effects of ginsenoside Rb1 on JNK in oxidative injury in cardiomyocytes [PDF]

open access: yesArchives of Pharmacal Research, 2012
Reactive oxygen species (ROS) can induce oxidative injury via iron interactions (i.e. Fenton chemistry and hydroxyl radical formation). Our prior work suggested that American ginseng berry extract and ginsenoside Re were highly cardioprotective against oxidant stress.
Jing, Li   +10 more
openaire   +2 more sources

Ginsenoside Rb1 Protects Against Diabetic Cardiomyopathy by Regulating the Adipocytokine Pathway

open access: yesJournal of Inflammation Research, 2022
Chenyang Zhang,1 Meixin Han,2 Xuelian Zhang,1 Hongna Tong,1 Xiaobo Sun,1 Guibo Sun1 1Institute of Medicinal Plant Development, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, People’s Republic of China; 2College of Pharmacy,
Zhang C   +5 more
doaj  

Characterization of Paenibacillus sp. MBT213 Isolated from Raw Milk and Its Ability to Convert Ginsenoside Rb1 into Ginsenoside Rd from Panax ginseng

open access: yesFood Science of Animal Resources, 2017
This study was conducted to isolate and characterize Paenibacillus sp. MBT213 possessing β-glucosidase activity from raw milk, and examine the enzymatic capacity on the hydrolysis of a major ginsenoside (Rb1).
Gereltuya Renchinkhand   +7 more
doaj   +1 more source

Ginsenoside Rb1 protects dopaminergic neurons from inflammatory injury induced by intranigral lipopolysaccharide injection

open access: yesNeural Regeneration Research, 2019
Accumulating studies suggest that neuroinflammation characterized by microglial overactivation plays a pivotal role in the pathogenesis of Parkinson’s disease.
Da-Wei Li   +6 more
doaj   +1 more source

Prebiotics enhance the biotransformation and bioavailability of ginsenosides in rats by modulating gut microbiota

open access: yesJournal of Ginseng Research, 2021
Background: Gut microbiota mainly function in the biotransformation of primary ginsenosides into bioactive metabolites. Herein, we investigated the effects of three prebiotic fibers by targeting gut microbiota on the metabolism of ginsenoside Rb1 in vivo.
Xiaoyan Zhang   +9 more
doaj   +1 more source

Evaluation of glucosidases of Aspergillus niger strain comparing with other glucosidases in transformation of ginsenoside Rb1 to ginsenosides Rg3

open access: yesJournal of Ginseng Research, 2014
The transformation of ginsenoside Rb1 into a specific minor ginsenoside using Aspergillus niger KCCM 11239, as well as the identification of the transformed products and the pathway via thin layer chromatography and high performance liquid chromatography
Kyung Hoon Chang   +3 more
doaj   +1 more source

Ginsenoside Rb1 Enhances Plaque Stability and Inhibits Adventitial Vasa Vasorum via the Modulation of miR-33 and PEDF

open access: yesFrontiers in Cardiovascular Medicine, 2021
Background: Atherosclerosis is closely associated with proliferation of the adventitial vasa vasorum, leading to the atherosclerotic plaque progression and vulnerability.
Xiaoyan Yang   +20 more
doaj   +1 more source

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