Results 71 to 80 of about 5,453 (156)

Chemical Comparison of Two Drying Methods of Mountain Cultivated Ginseng by UPLC-QTOF-MS/MS and Multivariate Statistical Analysis

Molecules, 2017
In traditional Chinese medicine practice, drying method is an essential factor to influence the components of Chinese medicinal herbs. In this study, an ultra-performance liquid chromatography quadrupole time-of-flight tandem mass spectrometry (UPLC-QTOF-
Xin-fang Xu, Shu-ya Xu, Ying Zhang, Hui Zhang, Meng-nan Liu, Huan Liu, Yan Gao, Xue Xue, Hui Xiong, Rui-chao Lin, Xiang-ri Li   +10 more
doaj   +1 more source

Unveiling the Crucial Nexus: Mitochondrial Quality Control as a Central Driver in Metabolic Dysfunction‐Associated Steatotic Liver Disease Pathogenesis

Cell Proliferation, Volume 59, Issue 2, February 2026.
Mitochondrial quality control (MQC) impairment plays a central role in driving the pathogenesis of metabolism‐associated steatotic liver disease (MASLD). Specifically, this is manifested as reduced mitophagy; increased mitochondrial fission and decreased fusion; and impaired mitochondrial biogenesis.
Wenkai Fu, Junqi Wang, Nan Lu, Zhijiang Guo, Sang‐Bing Ong, Yong Gao, Hao Zhou, Xing Chang, Miao Meng   +8 more
wiley   +1 more source

Ginsenoside Rb1 and mitochondria: A short review of the literature

Molecular and Cellular Probes, 2019
Mitochondria play a central role in various critical cellular processes, including energy synthesis, energy supply and apoptosis. Panax notoginseng, a commonly used traditional Chinese medicine, has various pharmacological effects on the human body. Ginsenosides are representative bioactive components of P. notoginseng.
Ping Zhou, Weijie Xie, Yifan Sun, Ziru Dai, Guang Li, Guibo Sun, Xiaobo Sun   +6 more
openaire   +2 more sources

Ginsenoside Rb1 inhibits proliferation and promotes apoptosis by regulating HMGB1 in uterine fibroid cells

Artificial Cells, Nanomedicine, and Biotechnology, 2019
To study the effects of ginsenoside Rb1 and the molecular mechanisms on proliferation and apoptosis of uterine fibroid cells, Rb1 + pc DNA3.1, Rb1 + pc DNA3.1-HMGB1, si-NC or si-HMGB1 was transfected into uterine fibroid cells by liposome method; the ...
Jianqiang Zhang, Jing Wang, Xinan Wu, Yuhui Wei   +3 more
doaj   +1 more source

Prevention of In‐Stent Restenosis After PCI by Saponin Natural Products: Inhibition of Platelet Activation

Journal of Cellular and Molecular Medicine, Volume 30, Issue 3, February 2026.
ABSTRACT Percutaneous coronary intervention (PCI) enables coronary revascularisation and restores haemodynamic stability but also carries risks of delayed complications including in‐stent restenosis (ISR), a chronic progressive disease with endovascular damage after PCI, which compromises the long‐term efficacy of PCI.
Xueli Lei, Chunlei Lv, Yu Zhang, Zhiyu Li, Hao Shen, Li Zhu   +5 more
wiley   +1 more source

Translational potential of ginsenoside Rb1 in managing progression of osteoarthritis

Journal of Orthopaedic Translation, 2016
Osteoarthritis (OA) is the most common degenerative joint disorder. Inflammatory cytokine plays an important role in OA progression. Previous studies have demonstrated that ginsenoside Rb1 would prevent inflammation and apoptosis in chondrocytes. However, we have not found any animal study reporting that Rb1 attenuates the severity of OA.In this study,
Chen Yuanfeng, LinSien, Sun Yuxin, Pan Xiaohua, Xiao Liubin, Zou Liyi, Ho Ki Wai, Li Gang   +7 more
openaire   +4 more sources

Attenuation of TNF-α-Induced Inflammatory Injury in Endothelial Cells by Ginsenoside Rb1 via Inhibiting NF-κB, JNK and p38 Signaling Pathways

Frontiers in Pharmacology, 2017
It is currently believed that inflammation plays a central role in the pathophysiology of atherosclerosis. Oxidative stress and redox-sensitive transcription factors are implicated in the process.
Ping Zhou, Ping Zhou, Ping Zhou, Ping Zhou, Shan Lu, Shan Lu, Shan Lu, Shan Lu, Yun Luo, Yun Luo, Yun Luo, Yun Luo, Shan Wang, Shan Wang, Shan Wang, Shan Wang, Ke Yang, Ke Yang, Ke Yang, Ke Yang, Yadong Zhai, Yadong Zhai, Yadong Zhai, Yadong Zhai, Guibo Sun, Guibo Sun, Guibo Sun, Guibo Sun, Xiaobo Sun, Xiaobo Sun, Xiaobo Sun, Xiaobo Sun   +31 more
doaj   +1 more source

New Insights Into Ginseng and Clove Supplementation: Alleviating Obesity by Reducing Leptin Resistance and Reshaping the Gut Microbiota

Food Frontiers, Volume 7, Issue 1, January 2026.
AEGC conferred substantial resistance to weight gain and reduced food intake. AEGC may alleviate LR by regulating the levels of LEP and ADP. AEGC elevated the diversity of gut microbiota and reconstructed the composition. Changes such as CAG‐873 in gut microbiota may be the reason why AEGC alleviates LR.
Weifeng Ni, Shen Yao, Shichao Li, Shichao Liu, Liwei Sun, Daqing Zhao, Zhengqi Dong, Siming Wang, Weinan Wang, Meichen Liu   +9 more
wiley   +1 more source

Ginsenoside Rb1 as an Anti-Diabetic Agent and Its Underlying Mechanism Analysis

Cells, 2019
Panax ginseng and Panax notoginseng, two well-known medical plants with economic value, have a long history of use for managing various diseases in Asian countries.
Ping Zhou, Weijie Xie, Shuaibing He, Yifan Sun, Xiangbao Meng, Guibo Sun, Xiaobo Sun   +6 more
doaj   +1 more source

Role of Macrophages in Cardiac Remodeling: Cues From Zebrafish Heart

Immunity, Inflammation and Disease, Volume 14, Issue 1, January 2026.
The figure illustrates the role of macrophage polarization in cardiac damage and repair, highlighting monocyte to M0, M1, and M2 macrophage differentiation. M1 macrophages, in response to pro‐inflammatory cytokines (e.g., IFNγ, TNF‐α, IL‐6), are involved in fibrosis and scarring in the heart.
Himanshu Gaur, Maram Hasan, Huseyin C. Yalcin   +2 more
wiley   +1 more source