Results 81 to 90 of about 5,735 (170)

Preparation of minor ginsenosides C-Mc, C-Y, F2, and C-K from American ginseng PPD-ginsenoside using special ginsenosidase type-I from Aspergillus niger g.848

open access: yesJournal of Ginseng Research, 2015
Background: Minor ginsenosides, those having low content in ginseng, have higher pharmacological activities. To obtain minor ginsenosides, the biotransformation of American ginseng protopanaxadiol (PPD)-ginsenoside was studied using special ginsenosidase
Chun-Ying Liu   +7 more
doaj   +1 more source

The Effects of Glycine and L-Arginine on Heat Stability of Ginsenoside Rb1

open access: yesBiological and Pharmaceutical Bulletin, 2007
To identify the effects of amino acids on the heat stability of ginsenoside Rb(1) (Rb(1)), Rb(1) was heat-processed at 120 degrees C with or without glycine or L-arginine. Rb(1) was changed into 20(S)-Rg(3), 20(R)-Rg(3), Rk(1), and Rg(5) by heat-processing through glycosyl elimination and epimerization of carbon-20 by SN1 reaction. Similarly, Rb(1) was
Kang, Ki Sung   +3 more
openaire   +3 more sources

Possible Role of Ginsenoside Rb1 on Regulation of Rat Liver Triglycerides.

open access: yesBiological and Pharmaceutical Bulletin, 2002
We have studied the effects of ginsenoside Rb1 (GRb1) on the change in lipid contents in rat liver. When GRb1 was administered intraperitoneally to rats, liver microsomal cytochrome P-450 content and NADPH-cytochrome P-450 reductase activity were lower than those in control rats.
Park, Ki-Hyun   +9 more
openaire   +3 more sources

Ginsenoside Rb1 ameliorates cisplatin-induced learning and memory impairments

open access: yesJournal of Ginseng Research, 2019
Ginsenoside Rb1 (Rb1), a dominant component from the extract of Panax ginseng root, exhibits neuroprotective functions in many neurological diseases. This study was intended to investigate whether Rb1 can attenuate cisplatin-induced memory impairments and explore the potential mechanisms.Cisplatin was injected intraperitoneally with a dose of 5 mg/kg ...
Chen Chen   +5 more
openaire   +3 more sources

Component analysis of cultivated ginseng, cultivated wild ginseng, and wild ginseng and the change of ginsenoside components in the process of red ginseng

open access: yesJournal of Pharmacopuncture, 2010
Objectives: The aim of this experiment is to provide an objective differentiation of cultivated ginseng, cultivated wild ginseng, and wild ginseng through component analysis, and to know the change of ginsenoside components in the process for making red ...
Jeong HS   +4 more
doaj   +1 more source

Ginsenoside Rb1-based dual-functional liposomes for enhanced siRNA delivery and synergistic anti-fibrotic therapy of hepatic fibrosis

open access: yesNano Research
Despite the high nucleic acid loading capacity, cationic liposomes (CLs) are facing challenges of insufficient nucleic acid drug release. Ginsenosides, natural product with a steroidal structure similar with cholesterol, not only have the potential to ...
Jiayu Li   +9 more
doaj   +1 more source

Ginsenoside Rb1 alleviates oxidative damage of HUVECs

open access: yesJichu yixue yu linchuang, 2020
Objective To explore the effect of ginsenoside Rb1 (gRb1) on oxidative damage of human umbilical vein endothelial cells (HUVECs) resulted from hydrogen peroxide (H2O2). Methods HUVECs were divided into control group, H2O2 group and gRb1 group. MTT assay was used to determine cell survival; annexin V-FITC/PI double staining was used to detect cell ...
openaire   +1 more source

Effect of a probiotic mixture on the biotransformation and bioavailability of deglycosylated ginsenosides

open access: yesJournal of Functional Foods
We aimed to investigate the effects of a probiotic mixture comprising Lactiplantibacillus plantarum, Bifidobacterium breve, Bifidobacterium animal subsp.
So Yeon Jeon   +9 more
doaj   +1 more source

Bioinformatics and molecular docking study of β-glucosidase J384W locus mutation

open access: yesXi'an Gongcheng Daxue xuebao
In order to improve the conversion efficiency of ginsenoside Rb1 by β-glucosidase, the key regions and sites involved in substrate recognition and binding in the conversion of ginsenoside Rb1 by β-glucosidase were obtained by molecular docking, the J384 ...
PAN Hong   +4 more
doaj   +1 more source

Ginsenoside Rb1 Improves Atherosclerosis by Inhibiting Endothelial Cell Pyroptosis. [PDF]

open access: yesOxid Med Cell Longev
Jiang X   +6 more
europepmc   +1 more source

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