Results 81 to 90 of about 8,127 (213)

Integrating mass spectrometry and systems biology for the modernization of natural medicines: From deciphering chemical complexity to holistic efficacy assessment

open access: yesVIEW, Volume 7, Issue 2, April 2026.
This review explores how mass spectrometry is transforming research in natural medicines, with Traditional Chinese medicine (TCM) as a primary exemplar. It details the application of advanced mass spectrometry in chemical analysis, the development of comprehensive quality control methods, and systematic research on the targeted mechanisms of single ...
Yudian Xu   +7 more
wiley   +1 more source

Ginsenoside-Rb1 Attenuates Dilated Cardiomyopathy in cTnTR141W Transgenic Mouse

open access: yesJournal of Pharmacological Sciences, 2010
Familial dilated cardiomyopathy (FDCM) is caused by defective genes and specific medicines are not currently available to treat this. Ginsenoside-Rb1 provides cardioprotection in the experimental models of myocardial ischemia-reperfusion injury. Here we investigate Rb1's effect on DCM in cTnT(R141W) transgenic mouse.
Haiping Zhao   +8 more
openaire   +4 more sources

Drug wastage among the elderly living in old aged homes in Hong Kong [PDF]

open access: yes, 2013
The extend of drug wastage among elderly living in old aged homes was never investigated. Upon the completion of the previous study on pharmaceutical services provided to elderly living in old aged homes, the amount of drugs wasted from 3,020 residents ...
Chan, EW   +4 more
core   +2 more sources

Targeting Autophagy in Ovarian Cancer: The Emerging Role of Ginsenosides

open access: yesCancer Medicine, Volume 15, Issue 3, March 2026.
ABSTRACT Background Ovarian cancer, the third most prevalent gynecological malignancy, is frequently diagnosed at an advanced stage owing to its asymptomatic early progression. Despite the application of conventional therapies, clinical management remains limited by adverse effects and the development of drug resistance.
Yuxin Guo   +4 more
wiley   +1 more source

Targeted metabolomics reveals the role of ginsenoside Rb1 in modulating inflammation and cellular senescence in sepsis-induced acute lung injury

open access: yesFood Science and Human Wellness
Sepsis-induced acute lung injury (ALI) is a major clinical challenge, with limited treatment options and high mortality. Ginsenoside Rb1, a bioactive compound derived from ginseng, has shown promising anti-inflammatory and antioxidative effects.
Fushuang Zheng   +3 more
doaj   +1 more source

MicroRNAs in Methamphetamine: Addiction, Neurotoxicity, and Therapeutic Potential

open access: yesMedComm – Future Medicine, Volume 5, Issue 1, March 2026.
The use of METH leads to the release of dopamine from the affected brain regions, including the nucleus accumbens (NAc), ventral tegmental area (VTA), prefrontal cortex (PFC), hippocampus (Hip), and striatum. This triggers signals that alter miRNA expression, which in turn leads to differential expression of target genes.
Yacoubou Abdoul Razak Mahaman   +7 more
wiley   +1 more source

Division of Biofunctional Evaluation(Research Center for Ethnomedicine) [PDF]

open access: yes, 2008
この論文は国立情報学研究所の学術雑誌公開支援事業により電子化されまし
東田 千尋, 横澤 隆子
core   +1 more source

Pharmacologically relevant drug interactions of sulfonylurea antidiabetics with common herbs [PDF]

open access: yes, 2018
Introduction: Sulfonylurea antidiabetics are insulin secretogogues useful in the treatment of type 2 diabetic patients. The probability of adverse drug interactions is high in patients taking sulfonylureas and other drugs including herbal medicines ...
Balasubramaniam, Rajkapoor.   +1 more
core   +2 more sources

Hot Water Extraction of Korean Red Ginseng (Panax ginseng C.A. Meyer) Using Vacuum‐Gas Substitution Under Oxygen‐Free Conditions: Effect on Ginsenosides and Antioxidant Activity

open access: yesJournal of Food Science, Volume 91, Issue 3, March 2026.
ABSTRACT This study investigated the effect of a vacuum‐gas substitution hot water extraction (HWE) process on Korean red ginseng (KRG) using a specially designed device. The yield, browning, antioxidant activity, and ginsenoside content of KRG extracted under oxygen‐free conditions (OFC, dissolved oxygen: 0.47 mg/L) were compared with those extracted ...
Kyo‐Yeon Lee   +2 more
wiley   +1 more source

Protective Effect of Ginsenoside Rb1 Against Lung Injury Induced by Intestinal Ischemia-Reperfusion in Rats

open access: yesMolecules, 2013
Intestinal ischemia-reperfusion (I/R) is a critical event in the pathogenesis of multiple organ dysfunction syndromes (MODS). The lungs are some of the most vulnerable organs that are impacted by intestinal I/R.
Guangtian Yang   +3 more
doaj   +1 more source

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