Results 81 to 90 of about 5,968 (172)

Ginsenoside Rb1 Attenuates Intestinal Ischemia Reperfusion Induced Renal Injury by Activating Nrf2/ARE Pathway

open access: yesMolecules, 2012
Intestinal ischemia reperfusion (IIR) is a serious clinical condition associated with simultaneous multiple organ dysfunction. The aim of this study was to investigate the effects of ginsenoside Rb1 on IIR induced renal injury in mice.
Zhong-Yuan Xia   +3 more
doaj   +1 more source

Effects of ginsenoside Rb1 on hypertrophic scar remodeling in rabbit model

open access: yesEuropean Journal of Pharmacology, 2015
Ginsenoside, one of the active compounds in Panax ginseng, inhibits tumor growth factor-beta 1 (TGF-β1) and reduces the level of collagen type 1. Ginsenoside Rb1 promotes burn wound healing. Our study evaluated the effects of ginsenoside Rb1 on hypertrophic scar remodeling.
Kwan Chul Tark   +5 more
openaire   +3 more sources

Preparation of minor ginsenosides C-Mc, C-Y, F2, and C-K from American ginseng PPD-ginsenoside using special ginsenosidase type-I from Aspergillus niger g.848

open access: yesJournal of Ginseng Research, 2015
Background: Minor ginsenosides, those having low content in ginseng, have higher pharmacological activities. To obtain minor ginsenosides, the biotransformation of American ginseng protopanaxadiol (PPD)-ginsenoside was studied using special ginsenosidase
Chun-Ying Liu   +7 more
doaj   +1 more source

The Effects of Glycine and L-Arginine on Heat Stability of Ginsenoside Rb1

open access: yesBiological and Pharmaceutical Bulletin, 2007
To identify the effects of amino acids on the heat stability of ginsenoside Rb(1) (Rb(1)), Rb(1) was heat-processed at 120 degrees C with or without glycine or L-arginine. Rb(1) was changed into 20(S)-Rg(3), 20(R)-Rg(3), Rk(1), and Rg(5) by heat-processing through glycosyl elimination and epimerization of carbon-20 by SN1 reaction. Similarly, Rb(1) was
Kang, Ki Sung   +3 more
openaire   +3 more sources

Molecular signaling of ginsenosides Rb1, Rg1, and Rg3 and their mode of actions

open access: yesJournal of Ginseng Research, 2018
Ginseng has gained its popularity as an adaptogen since ancient days because of its triterpenoid saponins, known as ginsenosides. These triterpenoid saponins are unique and classified as protopanaxatriol and protopanaxadiol saponins based on their glycosylation patterns.
Padmanaban Mohanan   +3 more
openaire   +3 more sources

Component analysis of cultivated ginseng, cultivated wild ginseng, and wild ginseng and the change of ginsenoside components in the process of red ginseng

open access: yesJournal of Pharmacopuncture, 2010
Objectives: The aim of this experiment is to provide an objective differentiation of cultivated ginseng, cultivated wild ginseng, and wild ginseng through component analysis, and to know the change of ginsenoside components in the process for making red ...
Jeong HS   +4 more
doaj   +1 more source

Ginsenoside Rb1-based dual-functional liposomes for enhanced siRNA delivery and synergistic anti-fibrotic therapy of hepatic fibrosis

open access: yesNano Research
Despite the high nucleic acid loading capacity, cationic liposomes (CLs) are facing challenges of insufficient nucleic acid drug release. Ginsenosides, natural product with a steroidal structure similar with cholesterol, not only have the potential to ...
Jiayu Li   +9 more
doaj   +1 more source

Effect of a probiotic mixture on the biotransformation and bioavailability of deglycosylated ginsenosides

open access: yesJournal of Functional Foods
We aimed to investigate the effects of a probiotic mixture comprising Lactiplantibacillus plantarum, Bifidobacterium breve, Bifidobacterium animal subsp.
So Yeon Jeon   +9 more
doaj   +1 more source

Ginsenoside Rb1 alleviates oxidative damage of HUVECs

open access: yesJichu yixue yu linchuang, 2020
Objective To explore the effect of ginsenoside Rb1 (gRb1) on oxidative damage of human umbilical vein endothelial cells (HUVECs) resulted from hydrogen peroxide (H2O2). Methods HUVECs were divided into control group, H2O2 group and gRb1 group. MTT assay was used to determine cell survival; annexin V-FITC/PI double staining was used to detect cell ...
openaire   +1 more source

Bioinformatics and molecular docking study of β-glucosidase J384W locus mutation

open access: yesXi'an Gongcheng Daxue xuebao
In order to improve the conversion efficiency of ginsenoside Rb1 by β-glucosidase, the key regions and sites involved in substrate recognition and binding in the conversion of ginsenoside Rb1 by β-glucosidase were obtained by molecular docking, the J384 ...
PAN Hong   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy