Results 71 to 80 of about 8,127 (213)

Chromosome‐Level Genome Assembly of the Allotetraploid Gynostemma pentaphyllum Provides Novel Insights Into the Biosynthesis of Ginsenoside and Gypenoside LVI

Plant Biotechnology Journal, EarlyView.
ABSTRACT Gynostemma pentaphyllum, a herb used in tea and traditional Chinese medicine, shows geographic variation in its production of valuable dammarane‐type ginsenosides and gypenoside LVI between populations from Suining (SN) and Nanning (NN). To elucidate the mechanisms underlying this differential metabolite accumulation, a chromosome‐level genome
Peina Zhou, Si‐Jie Liu, Lijin Huang, Yingping Wang, Xinyu Jiang, Wang Dong, Jianfeng Gong, Long Wang, Yuyin Zhao, Huiying Wang, Ping Li, Jia‐Yu Xue, Xu Lu   +12 more
wiley   +1 more source

Ginsenoside-Rb1 Induces ARPE-19 Proliferation and Reduces VEGF Release [PDF]

ISRN Ophthalmology, 2011
Rb1, a ginsenoside from ginseng root extract, possesses antiangiogenic effects, but its role on ocular cells has not been studied. We hypothesize that Rb1 inhibits the production of the angiogenic cytokine VEGF from ARPE-19 cells, leading to a significant reduction in the proliferation of ocular vasculatures.
Betts, Brandi S., Parvathaneni, Kalpana, Yendluri, Bharat B., Grigsby, Jeffery, Tsin, Andrew T. C.   +4 more
openaire   +2 more sources

Comparative analysis of the gut microbiota in people with different levels of ginsenoside Rb1 degradation to compound K.

PLoS ONE, 2013
Panax ginseng (family Araliaceae) which contains ginsenoside Rb1 as a main constituent is traditionally used as a remedy for cancer, inflammation, stress, and ageing.
Kyung-Ah Kim, Il-Hoon Jung, Se-Hoon Park, Young-Tae Ahn, Chul-Sung Huh, Dong-Hyun Kim   +5 more
doaj   +1 more source

Ginsenosides act as positive modulators of P2X4 receptors [PDF]

, 2018
We investigated the selectivity of protopanaxadiol ginsenosides from Panax ginseng acting as positive allosteric modulators on P2X receptors. ATP-induced responses were measured in stable cell lines overexpressing human P2X4 using a YOPRO-1 dye uptake ...
Asatryan, Brett A. Cromer, Chen, Choi, Franklin, Franklin, Gilbert, Helliwell, Jesus Angulo, Julie Sanderson, Khoja, Kim, Kshitija Dhuna, Leanne Stokes, Lucka Bibic, Martin J. Stebbing, Matsumura, Matthew Felgate, Nah, Orioli, Samuel Walpole, Stefan M. Bidula, Van Kampen, Zhao   +23 more
core   +3 more sources

Formulation and Pharmacological Evaluation of a Medicine‐Food Homology Herb‐Based Formula for Sleep Enhancement

Phytochemicals in Food and Medicine, Volume 1, Issue 2, June 2026.
This outlines the progress for developing a sleep‐modulating herbal formula (SMF). It begins with the identification of effective compounds and quality control, then uses network pharmacology and molecular docking to explain the mechanisms behind the observation found on the behavioural and neurobiological results in animal study.
Jasmine U. Ting, Chunxue Zhao, Jia Xu, Chenrui Liu, Yungang Tian, Min Ye, Tao Cui, Jian Huang   +7 more
wiley   +1 more source

Tissue-smashing based ultra-rapid extraction of chemical constituents in herbal medicines [PDF]

, 2014
postprin
Chen, C, Fan, Y, Li, P, Qi, LW, So, KF, Yan, CP   +5 more
core   +1 more source

Ginsenoside Rb1 Ameliorates Age‐Related Cognitive Impairment Potentially by Modulating the NF‐κB Signaling Pathway

Brain and Behavior, Volume 16, Issue 4, April 2026.
Ginsenoside Rb1 may alleviate age‐related cognitive impairment by suppressing hippocampal inflammation, potentially through modulation of the NF‐κB signaling pathway. Abstract Introduction: Age‐related cognitive impairment affects the quality of life of the elderly, contributing to a substantial healthcare burden.
Wei‐Feng Lu, Yu‐Zhen Zhang, Zhi‐Gang Chen, Qun‐Lin Xiao, Shi‐Ye Ke   +4 more
wiley   +1 more source

Ginsenoside Rb1, Compound K and 20(S)-Protopanaxadiol Attenuate High-Fat Diet-Induced Hyperlipidemia in Rats via Modulation of Gut Microbiota and Bile Acid Metabolism

Molecules
Hyperlipidemia, characterized by elevated serum lipid concentrations resulting from lipid metabolism dysfunction, represents a prevalent global health concern.
Kang-Xi Zhang, Yue Zhu, Shu-Xia Song, Qing-Yun Bu, Xiao-Yan You, Hong Zou, Guo-Ping Zhao   +6 more
doaj   +1 more source

Particulate Matter 2.5 Mediates Cutaneous Cellular Injury by Inducing Mitochondria-Associated Endoplasmic Reticulum Stress: Protective Effects of Ginsenoside Rb1

Antioxidants, 2019
The prevalence of fine particulate matter-induced harm to the human body is increasing daily. The aim of this study was to elucidate the mechanism by which particulate matter 2.5 (PM2.5) induces damage in human HaCaT keratinocytes and normal human dermal
Mei Jing Piao, Kyoung Ah Kang, Ao Xuan Zhen, Pincha Devage Sameera Madushan Fernando, Mee Jung Ahn, Young Sang Koh, Hee Kyoung Kang, Joo Mi Yi, Yung Hyun Choi, Jin Won Hyun   +9 more
doaj   +1 more source

Synthesis of Esters of Ginsenoside Metabolite M1 and Their Cytotoxicity on MGC80-3 Cells [PDF]

, 2013
molecule
Ke-ke Li, Li-rong Chen, Wen-fang Li, Xiao-jie Gong, Zheng-ning Li   +4 more
core   +2 more sources