Analysis of Ginsenoside Isomers by Inlet Ionization-High Resolution Mass Spectrometry
Zhipu XuebaoThe ginsenoside isomers were analyzed and distinguished by using inlet ionization-high resolution mass spectrometry technology under positive and negative ion modes with optimum inlet temperatures.
Yun-long GUO +7 more
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Induction of apoptosis in Lewis lung carcinoma cells by an intestinal bacterial metabolite produced from orally administered ginseng protopanaxadiol saponins [PDF]
, 2000 The present study demonstrated that oral administration of an intestinal bacterial metabolite (M1) of protopanaxadiol-type saponin significantly inhibited the tumor growth at the implantation site after intrapulmonary implantation of Lewis lung carcinoma
Hasegawa Hideo +3 more
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Anti-inflammatory effects of ginsenosides from Panax ginseng and their structural analogs [PDF]
, 2010 Ginsenosides (G) are biologically active saponin compounds found inPanax ginseng. Although these compounds are reported to possess numerous biological activities, recent issues have arisen regarding their immunosuppressive and anti-inflammatory roles in ...
Cho, J, Park, J
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Ginsenoside Rh2 inhibits metastasis of glioblastoma multiforme through Akt-regulated MMP13
Tumor Biology, 2015 Glioblastoma multiforme (GBM) is the most malignant type of primary brain tumor. Although the growth of the tumor cells in a relatively closed space may partially account for its malignancy, highly invasive nature of glioblastoma cells has been suggested to be the main reason for the failure of current therapeutic approaches. Ginsenoside Rh2 (GRh2) has
Ning, Guan +5 more
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Differential antiangiogenic and anticancer activities of the active metabolites of ginsenoside Rg3
Journal of Ginseng ResearchBackground: Epimers of ginsenoside Rg3 (Rg3) have a low bioavailability and are prone to deglycosylation, which produces epimers of ginsenoside Rh2 (S–Rh2 and R–Rh2) and protopanaxadiol (S-PPD and R-PPD). The aim of this study was to compare the efficacy
Maryam Nakhjavani +7 more
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Ginseng Purified Dry Extract, BST204, Improved Cancer Chemotherapy-Related Fatigue and Toxicity in Mice [PDF]
, 2015 Cancer related fatigue (CRF) is one of the most common side effects of cancer and its treatments. A large proportion of cancer patients experience cancer-related physical and central fatigue so new strategies are needed for treatment and improved ...
Hyun Soo Shim +5 more
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Frontiers in ImmunologyObjectLiver fibrosis is a key stage in chronic liver disease, but targeted treatments are scarce. Pien Tze Huang (PZH), a traditional Chinese medicine, shows anti-fibrotic potential, though its mechanisms are not fully understood.MethodA liver fibrosis ...
Xiaoting Hong +9 more
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Membrane cholesterol delays cellular apoptosis induced by ginsenoside Rh2, a steroid saponin
Toxicology and Applied Pharmacology, 2018 Saponins exhibit several biological and pharmacological activities, such as antibacterial, anti-inflammatory and anticancer effects. Many studies attribute their activities to their interactions with cholesterol. In this study, we focus on the steroid saponin ginsenoside Rh2, one of the active principles of Panax ginseng root.
Verstraeten, Sandrine +5 more
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十全大補湯のストレス負荷とP. gingivalis感染ラットにおける歯槽骨吸収に対する改善効果 [PDF]
, 2016 Juzentaihoto (JTX) is a traditional Japanese medicine that consists of 10 herbs. The purpose of this study was to evaluate the efficacy of multi-herbal medicine JTX as a preventive and therapeutic drug for periodontal bone resorption and for reducing ...
武田 織英
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Effects of ginsenoside Rh2 on growth and migration of pancreatic cancer cells
World Journal of Gastroenterology, 2013 To investigate the effects of ginsenoside Rh2 on the human pancreatic cancer cell line Bxpc-3.The human pancreatic cancer cell line Bxpc-3 was cultured in vitro and treated with or without ginsenoside Rh2. Growth rates for Bxpc-3 cells were assessed by methyl thiazolyl tetrazolium (MTT) and colony formation assays.
Xi-Ping, Tang +4 more
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