Results 101 to 110 of about 3,001 (186)

Ginsenosides Rg3 and Rh2 inhibit the activation of AP-1 and protein kinase A pathway in lipopolysaccharide/interferon-γ-stimulated BV-2 microglial cells [PDF]

, 2018
The anti-inflammatory effect of ginsenosides Rg3 and Rh2, which improves ischemic brain injury induced by middle cerebral artery occlusion, was investigated in lipopolysaccharide (LPS) and IFN-γ-induced murine BV-2 microglial cells.
김희선
core   +1 more source

Evaluation of glucosidases of Aspergillus niger strain comparing with other glucosidases in transformation of ginsenoside Rb1 to ginsenosides Rg3

Journal of Ginseng Research, 2014
The transformation of ginsenoside Rb1 into a specific minor ginsenoside using Aspergillus niger KCCM 11239, as well as the identification of the transformed products and the pathway via thin layer chromatography and high performance liquid chromatography
Kyung Hoon Chang, Mi Na Jo, Kee-Tae Kim, Hyun-Dong Paik   +3 more
doaj   +1 more source

Mediation of Beta-Endorphin by Ginsenoside Rh2 to Lower Plasma Glucose in Streptozotocin-Induced Diabetic Rats [PDF]

, 2009
We investigated the plasma glucose-lowering mechanism(s) of Rh2, a ginsenoside derived from Panax ginseng, in rats with streptozotocin- induced diabetes (STZ-diabetic rats).
LAI, DAR-MING;TU, YONG-KWANG;LIU, I-MIN;CHENG, JUEI-TANG, 賴達明;杜永光;劉怡旻;鄭瑞堂   +1 more
core  

Analysis of Ginsenoside Isomers by Inlet Ionization-High Resolution Mass Spectrometry

Zhipu Xuebao
The ginsenoside isomers were analyzed and distinguished by using inlet ionization-high resolution mass spectrometry technology under positive and negative ion modes with optimum inlet temperatures.
Yun-long GUO, Hong-yue CHI, Yang WANG, Fei ZHENG, Yu-lin DAI, Xin HUANG, Hao YUE, Shu-ying LIU   +7 more
doaj   +1 more source

Component analysis of cultivated ginseng, cultivated wild ginseng, and wild ginseng and the change of ginsenoside components in the process of red ginseng

Journal of Pharmacopuncture, 2010
Objectives: The aim of this experiment is to provide an objective differentiation of cultivated ginseng, cultivated wild ginseng, and wild ginseng through component analysis, and to know the change of ginsenoside components in the process for making red ...
Jeong HS, Lim CS, Cha BC, Choi SH, Kwon KR   +4 more
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Differential antiangiogenic and anticancer activities of the active metabolites of ginsenoside Rg3

Journal of Ginseng Research
Background: Epimers of ginsenoside Rg3 (Rg3) have a low bioavailability and are prone to deglycosylation, which produces epimers of ginsenoside Rh2 (S–Rh2 and R–Rh2) and protopanaxadiol (S-PPD and R-PPD). The aim of this study was to compare the efficacy
Maryam Nakhjavani, Eric Smith, Kenny Yeo, Yoko Tomita, Timothy J. Price, Andrea Yool, Amanda R. Townsend, Jennifer E. Hardingham   +7 more
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Metabolic engineering of tobacco for heterologous production of rare ginsenosides CK and Rh2

Frontiers in Plant Science
Rare ginsenosides, such as compound K (CK) and Rh2, possess potent pharmacological activities but are present at extremely low levels in natural Panax ginseng.
Linggai Cao, Linggai Cao, Xuemeng Li, Shanshan Lang, Yan Chen, Yan Chen, Ping Dong, Ping Dong, Jie Zhang, Jie Liu, Pan Zhang, Shizhou Yu, Jianfeng Zhang   +12 more
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Bioinformatics based exploration of the anti-liver fibrosis mechanism of Pien Tze Huang via EGFR/JAK1/STAT3 pathway

Frontiers in Immunology
ObjectLiver fibrosis is a key stage in chronic liver disease, but targeted treatments are scarce. Pien Tze Huang (PZH), a traditional Chinese medicine, shows anti-fibrotic potential, though its mechanisms are not fully understood.MethodA liver fibrosis ...
Xiaoting Hong, Yonghua Ye, Chunfeng Lin, Miaolan Zheng, Fan Lin, Qing Xiong, Wei Xu, Huang Li, Yuqin Zhang, Haiyin Zheng   +9 more
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A multicomponent microemulsion using rational combination strategy improves lung cancer treatment through synergistic effects and deep tumor penetration

Drug Delivery, 2017
Previously, we have developed a multicomponent-based microemulsion composed of etoposide, coix seed oil, and ginsenoside Rh2 (ECG-MEs). In this study, our goal was to validate the feasibility of ECG-MEs in lung cancer treatment and explore the mechanism ...
Ding Qu, Mengfei Guo, Yue Qin, Lixiang Wang, Bing Zong, Yunyan Chen, Yan Chen   +6 more
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Remodeling the tumor immune microenvironment through hydrogel encapsulated G-Rh2 in situ vaccine and systemic immunotherapy

Materials Today Bio
Ginsenoside Rh2 (G-Rh2) is a vital bioactive compound in Traditional Chinese Medicine, celebrated for its strong pharmacological properties, particularly its potent antitumor effects.
Chunhua Li, Dan Lei, Yudong Huang, Yuanhao Jing, Wanru Wang, Lanqi Cen, Zijian Wei, Anni Chen, Xiaoyu Feng, Yushu Wang, Lixia Yu, Ying Chen, Rutian Li   +12 more
doaj   +1 more source