Results 11 to 20 of about 653 (163)
Gintonin absorption in intestinal model systems
Journal of Ginseng Research, 2018 Background: Recently, we identified a novel ginseng-derived lysophosphatidic acid receptor ligand, called gintonin. We showed that gintonin induces [Ca2+]i transient-mediated morphological changes, proliferation, and migration in cells expressing ...
Sun-Hye Choi +2 more
exaly +5 more sources
Ginseng Gintonin Contains Ligands for GPR40 and GPR55 [PDF]
Molecules, 2020 Gintonin, a novel ginseng-derived glycolipoprotein complex, has an exogenous ligand for lysophosphatidic acid (LPA) receptors. However, recent lipid analysis of gintonin has shown that gintonin also contains other bioactive lipids besides LPAs, including
Sun-Hye Choi, Rami Lee, Hong-Ik Hwang
exaly +5 more sources
Molecular Mechanisms of Large-Conductance Ca 2+ [PDF]
Evidence-Based Complementary and Alternative Medicine, Volume 2013, Issue 1, 2013., 2013 Gintonin is a unique lysophosphatidic acid (LPA) receptor ligand found in Panax ginseng. Gintonin induces transient [Ca2+]i through G protein-coupled LPA receptors. Large-conductance Ca2+-activated K+ (BKCa) channels are expressed in blood vessels and
B. H. Lee +7 more
core +5 more sources
Bioactive lipids in gintonin-enriched fraction from ginseng
Journal of Ginseng Research, 2019 Background: Ginseng is a traditional herbal medicine for human health. Ginseng contains a bioactive ligand named gintonin. The active ingredient of gintonin is lysophosphatidic acid C18:2 (LPA C18:2).
Hee-Jung Cho +2 more
exaly +5 more sources
Effect of the Gintonin-Enriched Fraction on Glucagon-Like-Protein-1 Release [PDF]
Molecules, 2021 Ginseng-derived gintonin reportedly contains functional lysophosphatidic acids (LPAs) as LPA receptor ligands. The effect of the gintonin-enriched fraction (GEF) on in vitro and in vivo glucagon-like protein-1 (GLP-1) secretion, which is known to ...
Rami Lee +7 more
doaj +5 more sources
Ongoing Research on the Role of Gintonin in the Management of Neurodegenerative Disorders [PDF]
Cells, 2020 Neurodegenerative disorders, namely Parkinson’s disease (PD), Huntington’s disease (HD), Alzheimer’s disease (AD), and multiple sclerosis (MS), are increasingly major health concerns due to the increasingly aged population worldwide.
Muhammad Ikram +2 more
exaly +5 more sources
Preparation of Red Ginseng Marc-Derived Gintonin and Its Application as a Skin Nutrient [PDF]
Nutrients, 2023 Ginseng is one of the traditional herbal medicines for tonic. Gintonin is a new material derived from white/red ginseng and its lysophosphatidic acids (LPAs) play as a ligand for G protein-coupled LPA receptors. Korean red ginseng marc (KRGM) is a by-product after the KRG processes.
Rami Lee, Ji Hun Kim, Hong-Ik Hwang
exaly +4 more sources
Ginseng gintonin, aging societies, and geriatric brain diseases
Integrative Medicine Research, 2021 Background: A dramatic increase in aging populations and low birth rates rapidly drive aging societies and increase aging-associated neurodegenerative diseases.
Sun-Hye Choi +8 more
doaj +3 more sources
A Role of Ginseng and Its Constituents in the Treatment of Central Nervous System Disorders [PDF]
Evidence-Based Complementary and Alternative Medicine, Volume 2016, Issue 1, 2016., 2016 Ginseng, a perennial plant belonging to the Panax genus of the Araliaceae family, has been used in China, Korea, and Japan as a traditional herbal medicine for thousands of years.
Akihiro Asakawa +9 more
core +6 more sources
Gintonin influences the morphology and motility of adult brain neurons via LPA receptors
Journal of Ginseng Research, 2021 Background: Gintonin is an exogenous ginseng-derived G-protein-coupled lysophosphatidic acid (LPA) receptor ligand. LPA induces in vitro morphological changes and migration through neuronal LPA1 receptor.
Do-Geun Kim +8 more
doaj +3 more sources